Structural mechanism of the antigen recognition by the L1 cell adhesion molecule antibody A10-A3

FEBS Letters

Volumn 585, Issue 1, 2011, Pages 153-158

  Wei, Chun Hua ^a,b,f   Lee, Eung Suk ^g   Jeon, Jeong Yi ^a   Heo, Yong Seok ^d   Kim, Seung Jun ^e   Jeon, Young Ho ^b,f   Kim, Kyung Hyun ^g   Hong, Hyo Jeong ^c   Ryu, Seong Eon ^a  

^a Hanyang University   (South Korea)

^b University of Science and Technology (UST)   (South Korea)

^c Kangwon National University   (South Korea)

^d Konkuk University   (South Korea)

^e Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^f Korea Basic Science Institute (KBSI)   (South Korea)

^g Korea University   (South Korea)

Author keywords

A10 A3; Antibody; Cancer; Crystal structure; L1CAM

Indexed keywords

IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY A10 A3; NERVE CELL ADHESION MOLECULE L1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIGEN BINDING; ANTIGEN RECOGNITION; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CANCER GROWTH; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DESIGN; EPITOPE MAPPING; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; ANTIGEN-ANTIBODY COMPLEX; ANTIGENS; BINDING SITES; CRYSTALLIZATION; EPITOPE MAPPING; EPITOPES; HEK293 CELLS; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; MICE; MODELS, MOLECULAR; NEURAL CELL ADHESION MOLECULE L1; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; X-RAY DIFFRACTION;

MUS MUSCULUS;

EID: 78650874809     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.11.028     Document Type: Article

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