메뉴 건너뛰기




Volumn 16, Issue 14, 2010, Pages 3571-3580

L1 cell adhesion molecule is a novel therapeutic target in intrahepatic cholangiocarcinoma

Author keywords

[No Author keywords available]

Indexed keywords

GEMCITABINE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY A10 A3; NERVE CELL ADHESION MOLECULE L1; NERVE CELL ADHESION MOLECULE L1 ANTIBODY; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

EID: 77954711918     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-09-3075     Document Type: Article
Times cited : (37)

References (46)
  • 1
    • 0034982536 scopus 로고    scopus 로고
    • Increasing incidence and mortality of primary intrahepatic cholangiocarcinoma in the United States
    • DOI 10.1053/jhep.2001.25087
    • Patel T. Increasing incidence and mortality of primary intrahepatic cholangiocarcinoma in the United States. Hepatology 2001;33:1353-57. (Pubitemid 32496970)
    • (2001) Hepatology , vol.33 , Issue.6 , pp. 1353-1357
    • Patel, T.1
  • 2
    • 0035000597 scopus 로고    scopus 로고
    • Increase in mortality rates from intrahepatic cholangiocarcinoma in England and Wales 1968-1998
    • Taylor-Robinson SD, Toledano MB, Arora S, et al. Increase in mortality rates from intrahepatic cholangiocarcinoma in England and Wales 1968-1998. Gut 2001;48:816-20.
    • (2001) Gut , vol.48 , pp. 816-820
    • Taylor-Robinson, S.D.1    Toledano, M.B.2    Arora, S.3
  • 5
    • 0028966352 scopus 로고
    • Aggressive surgical resection for cholangiocarcinoma
    • Washburn WK, Lewis WD, Jenkins RL. Aggressive surgical resection for cholangiocarcinoma. Arch Surg 1995;130:270-6.
    • (1995) Arch Surg , vol.130 , pp. 270-276
    • Washburn, W.K.1    Lewis, W.D.2    Jenkins, R.L.3
  • 6
    • 0036444730 scopus 로고    scopus 로고
    • Results of surgical treatment for intrahepatic cholangiocarcinoma and clinicopathological factors influencing survival
    • DOI 10.1046/j.1365-2168.2002.02268.x
    • Ohtsuka M, Ito H, Kimura F, et al. Results of surgical treatment for intrahepatic cholangiocarcinoma and clinicopathological factors influencing survival. Br J Surg 2002;89:1525-31. (Pubitemid 35404319)
    • (2002) British Journal of Surgery , vol.89 , Issue.12 , pp. 1525-1531
    • Ohtsuka, M.1    Ito, H.2    Kimura, F.3    Shimizu, H.4    Togawa, A.5    Yoshidome, H.6    Miyazaki, M.7
  • 7
    • 0027429723 scopus 로고
    • Axonal glycoproteins with immunoglobulin- And fibronectin type III- related domains in vertebrates: Structural features, binding activities, and signal transduction
    • Brummendorf T, Rathjen FG. Axonal glycoproteins with immunoglobulin- and fibronectin type III-related domains in vertebrates: structural features, binding activities, and signal transduction. J Neurochem 1993;61:1207-19. (Pubitemid 23285076)
    • (1993) Journal of Neurochemistry , vol.61 , Issue.4 , pp. 1207-1219
    • Brummendorf, T.1    Rathjen, F.G.2
  • 8
    • 0030273263 scopus 로고    scopus 로고
    • The L1 family of neural cell adhesion molecules: Old proteins performing new tricks
    • DOI 10.1016/S0896-6273(00)80192-0
    • Hortsch M. The L1 family of neural cell adhesion molecules: old proteins performing new tricks. Neuron 1996;17:587-93. (Pubitemid 26365339)
    • (1996) Neuron , vol.17 , Issue.4 , pp. 587-593
    • Hortsch, M.1
  • 9
    • 0021046979 scopus 로고
    • L1 mono- And polyclonal antibodies modify cell migration in early postnatal mouse cerebellum
    • Lindner J, Rathjen FG, Schachner M. L1 mono- and polyclonal antibodies modify cell migration in early postnatal mouse cerebellum. Nature 1983;305:427-30. (Pubitemid 14225148)
    • (1983) Nature , vol.305 , Issue.5933 , pp. 427-430
    • Lindner, J.1    Rathjen, F.G.2    Schachner, M.3
  • 10
    • 0026669747 scopus 로고
    • The cell adhesion molecule L1 has a specific role in neural cell migration
    • Miura M, Asou H, Uyemura K. The cell adhesion molecule L1 has a specific role in neural cell migration. J Biol Chem 1992;267:10752-58.
    • (1992) J Biol Chem , vol.267 , pp. 10752-10758
    • Miura, M.1    Asou, H.2    Uyemura, K.3
  • 11
    • 0030666794 scopus 로고    scopus 로고
    • Disruption of the mouse L1 gene leads to malformations of the nervous system
    • DOI 10.1038/ng1197-346
    • Dahme M, Bartsch U, Martini R, Anliker B, Schachner M, Mantei N. Disruption of the mouse L1 gene leads to malformations of the nervous system. Nat Genet 1997;17:346-49. (Pubitemid 27476003)
    • (1997) Nature Genetics , vol.17 , Issue.3 , pp. 346-349
    • Dahme, M.1    Bartsch, U.2    Martini, R.3    Anliker, B.4    Schachner, M.5    Mantei, N.6
  • 12
    • 0033564746 scopus 로고    scopus 로고
    • Abnormalities in neuronal process extension, hippocampal development, and the ventricular system of L1 knockout mice
    • Demyanenko GP, Tsai AY, Maness PF. Abnormalities in neuronal process extension, hippocampal development, and the ventricular system of L1 knockout mice. J Neurosci 1999;19:4907-20.
    • (1999) J Neurosci , vol.19 , pp. 4907-4920
    • Demyanenko, G.P.1    Tsai, A.Y.2    Maness, P.F.3
  • 13
    • 0023409795 scopus 로고
    • Characterization of the cell adhesion molecules L1, N-CAM and J1 in the mouse intestine
    • Thor G, Probstmeier R, Schachner M. Characterization of the cell adhesion molecules L1, N-CAM and J1 in the mouse intestine. EMBO J 1987;6:2581-86.
    • (1987) EMBO J , vol.6 , pp. 2581-2586
    • Thor, G.1    Probstmeier, R.2    Schachner, M.3
  • 14
    • 0029845321 scopus 로고    scopus 로고
    • L1 adhesion molecule on human lymphocytes and monocytes: Expression and involvement in binding to αvβ3 integrin
    • Ebeling O, Duczmal A, Aigner S, et al. L1 adhesion molecule on human lymphocytes and monocytes: expression and involvement in binding to αvβ3 integrin. Eur J Immunol 1996:262508-16.
    • (1996) Eur J Immunol , pp. 262508-262516
    • Ebeling, O.1    Duczmal, A.2    Aigner, S.3
  • 15
    • 0031131885 scopus 로고    scopus 로고
    • Expression and Regulation of the Neural Cell Adhesion Molecule L1 on Human Cells of Myelomonocytic and Lymphoid Origin
    • Pancook JD, Reisfeld RA, Varki N, Vitiello A, Fox RI, Montgomery AMP. Expression and regulation of the neural cell adhesion molecule L1 on human cells of myelomonocytic and lymphoid origin. J Immunol 1997;158:4413-21. (Pubitemid 127483945)
    • (1997) Journal of Immunology , vol.158 , Issue.9 , pp. 4413-4421
    • Pancook, J.D.1    Reisfeld, R.A.2    Varki, N.3    Vitiello, A.4    Fox, R.I.5    Montgomery, A.M.P.6
  • 16
    • 0032576548 scopus 로고    scopus 로고
    • The cell adhesion molecule L1 is developmentally regulated in the renal epithelium and is involved in kidney branching morphogenesis
    • DOI 10.1083/jcb.143.7.2067
    • Debiec H, Christensen EI, Ronco PM. The cell adhesion molecule L1 is developmentally regulated in the renal epithelium and is involved in kidney branching morphogenesis. J Cell Biol 1998;143:2067-79. (Pubitemid 29022625)
    • (1998) Journal of Cell Biology , vol.143 , Issue.7 , pp. 2067-2079
    • Debiec, H.1    Christensen, E.I.2    Ronco, P.M.3
  • 17
    • 0032733643 scopus 로고    scopus 로고
    • Immunolocalization of the neural cell adhesion molecule L1 in epithelia of rodents
    • DOI 10.1007/s004419900063
    • Nolte C, Moos M, Schachner M. Immunolocalization of the neural cell adhesion molecule L1 in epithelia of rodents. Cell Tissue Res 1999;298:261-73. (Pubitemid 29512078)
    • (1999) Cell and Tissue Research , vol.298 , Issue.2 , pp. 261-273
    • Nolte, C.1    Moos, M.2    Schachner, M.3
  • 18
    • 0029925720 scopus 로고    scopus 로고
    • Gene expression of neural cell adhesion molecule L1 in malignant gliomas and biological significance of L1 in glioma invasion
    • Izumoto S, Ohnishi T, Arita N, Hiraga S, Taki T, Hayakawa T. Gene expression of neural cell adhesion molecule L1 in malignant gliomas and biological significance of L1 in glioma invasion. Cancer Res 1996;56:1440-4. (Pubitemid 26080991)
    • (1996) Cancer Research , vol.56 , Issue.6 , pp. 1440-1444
    • Izumoto, S.1    Ohnishi, T.2    Arita, N.3    Hiraga, S.4    Taki, T.5    Hayakawa, T.6
  • 19
    • 0034745221 scopus 로고    scopus 로고
    • A comparison of targeting of neuroblastoma with mIGB and anti L1-CAM antibody mAb chCE7: Therapeutic efficacy in a neuroblastoma patients
    • Hoefnagel CA, Rutgers M, Buitenhuis CK, et al. A comparison of targeting of neuroblastoma with mIGB and anti L1-CAM antibody mAb chCE7: therapeutic efficacy in a neuroblastoma patients. Eur J Nucl Med 2001;28:359-68.
    • (2001) Eur J Nucl Med , vol.28 , pp. 359-368
    • Hoefnagel, C.A.1    Rutgers, M.2    Buitenhuis, C.K.3
  • 20
    • 0036024585 scopus 로고    scopus 로고
    • Overexpression of the cell adhesion molecule L1 is associated with metastasis in cutaneous malignant melanoma
    • Thies A, Schachner M, Moll I, et al. Overexpression of the cell adhesion molecule L1 is associated with metastasis in cutaneous malignant melanoma. Eur J Cancer 2002;38:1708-16.
    • (2002) Eur J Cancer , vol.38 , pp. 1708-1716
    • Thies, A.1    Schachner, M.2    Moll, I.3
  • 21
    • 12944259073 scopus 로고    scopus 로고
    • The L1 cell adhesion molecule is induced in renal cancer cells and correlates with metastasis in clear cell carcinomas
    • Allory Y, Matsuoka Y, Bazille C, Christensen EI, Ronco P, Debiec H. The L1 cell adhesion molecule is induced in renal cancer cells and correlates with metastasis in clear cell carcinomas. Clin Cancer Res 2005;11:1190-7. (Pubitemid 40175770)
    • (2005) Clinical Cancer Research , vol.11 , Issue.3 , pp. 1190-1197
    • Allory, Y.1    Matsuoka, Y.2    Bazille, C.3    Christensen, E.I.4    Ronco, P.5    Debiec, H.6
  • 23
    • 3142692818 scopus 로고    scopus 로고
    • The L1CAM extracellular region: Multi-domain protein with modular and cooperative binding modes
    • Haspel J, Grumet M. The L1CAM extracellular region: multi-domain protein with modular and cooperative binding modes. Front Biosci 2003;8:1210-25.
    • (2003) Front Biosci , vol.8 , pp. 1210-1225
    • Haspel, J.1    Grumet, M.2
  • 24
    • 20844462570 scopus 로고    scopus 로고
    • L1 augments cell migration and tumor growth but not β3 integrin expression in ovarian carcinomas
    • Gast D, Riedle S, Schabath H, et al. L1 augments cell migration and tumor growth but not β3 integrin expression in ovarian carcinomas. Int J Cancer 2005;115:658-65.
    • (2005) Int J Cancer , vol.115 , pp. 658-665
    • Gast, D.1    Riedle, S.2    Schabath, H.3
  • 25
    • 0035158462 scopus 로고    scopus 로고
    • Involvement of integrin α(v)β(3) and cell adhesion molecule L1 in transendothelial migration of melanoma cells
    • Voura EB, Ramjeesingh RA, Montgomery AM, Siu CH. Involvement of integrin α(v)β(3) and cell adhesion molecule L1 in transendothelial migration of melanoma cells. Mol Biol Cell 2001;12:2699-710.
    • (2001) Mol Biol Cell , vol.12 , pp. 2699-2710
    • Voura, E.B.1    Ramjeesingh, R.A.2    Montgomery, A.M.3    Siu, C.H.4
  • 27
    • 3142733866 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase (ERK)-dependent gene expression contributes to L1 cell adhesion molecule-dependent motility and invasion
    • DOI 10.1074/jbc.M404075200
    • Silletti S, Yebra M, Perez B, Cirulli V, McMahon M, Montgomery AM. Extracellular signal-regulated kinase (ERK)-dependent gene expression contributes to L1 cell adhesion molecule-dependent motility and invasion. J Biol Chem 2004;279:28880-8. (Pubitemid 38915755)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.28 , pp. 28880-28888
    • Silletti, S.1    Yebra, M.2    Perez, B.3    Cirulli, V.4    McMahon, M.5    Montgomery, A.M.P.6
  • 28
    • 0035969235 scopus 로고    scopus 로고
    • Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins
    • Mechtersheimer S, Gutwein P, Agmon-Levin N, et al. Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins. J Cell Biol 2001;155:661-73.
    • (2001) J Cell Biol , vol.155 , pp. 661-673
    • Mechtersheimer, S.1    Gutwein, P.2    Agmon-Levin, N.3
  • 30
    • 0037318306 scopus 로고    scopus 로고
    • ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in released membrane vesicles
    • Gutwein P, Mechtersheimer S, Riedle S, et al. ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in released membrane vesicles. FASEB J 2003;17:292-4.
    • (2003) FASEB J , vol.17 , pp. 292-294
    • Gutwein, P.1    Mechtersheimer, S.2    Riedle, S.3
  • 32
    • 31544439090 scopus 로고    scopus 로고
    • Efficient inhibition of intra-peritoneal tumor growth and dissemination of human ovarian carcinoma cells in nude mice by anti-L1-cell adhesion molecule monoclonal antibody treatment
    • DOI 10.1158/0008-5472.CAN-05-1818
    • Arlt MJE, Novak-Hofer I, Gast D, et al. Efficient inhibition of intraperitoneal tumor growth and dissemination of human ovarian carcinoma cells in nude mice by anti-L1-cell adhesion molecule monoclonal antibody treatment. Cancer Res 2006;66:936-43. (Pubitemid 43165961)
    • (2006) Cancer Research , vol.66 , Issue.2 , pp. 936-943
    • Arlt, M.J.E.1    Novak-Hofer, I.2    Gast, D.3    Gschwend, V.4    Moldenhauer, G.5    Grunberg, J.6    Honer, M.7    Schubiger, P.A.8    Altevogt, P.9    Kruger, A.10
  • 33
    • 51049101689 scopus 로고    scopus 로고
    • Targeting cancer stem cells through L1CAM suppresses gliomas growth
    • Bao S, Wu Q, Li Z, et al. Targeting cancer stem cells through L1CAM suppresses gliomas growth. Cancer Res 2008;68:6043-8.
    • (2008) Cancer Res , vol.68 , pp. 6043-6048
    • Bao, S.1    Wu, Q.2    Li, Z.3
  • 34
    • 0035206192 scopus 로고    scopus 로고
    • Establishment and characterization of chromosomal aberrations in human cholangiocarcinoma cell lines by cross-species color banding
    • Kim DG, Park SY, You KR, et al. Establishment and characterization of chromosomal aberrations in human cholangiocarcinoma cell lines by cross-species color banding. Genes Chromosomes Cancer 2001;30:48-56.
    • (2001) Genes Chromosomes Cancer , vol.30 , pp. 48-56
    • Kim, D.G.1    Park, S.Y.2    You, K.R.3
  • 35
    • 28444482742 scopus 로고    scopus 로고
    • Heat shock 70 kDa protein 8 isoform 1 is expressed on the surface of human embryonic stem cells and downregulated upon differentiation
    • Son YS, Park JH, Kang YK, et al. Heat shock 70 kDa protein 8 isoform 1 is expressed on the surface of human embryonic stem cells and downregulated upon differentiation. Stem Cells 2005;23:1502-13.
    • (2005) Stem Cells , vol.23 , pp. 1502-1513
    • Son, Y.S.1    Park, J.H.2    Kang, Y.K.3
  • 36
    • 33846660562 scopus 로고    scopus 로고
    • MUC4 is a novel prognostic factor of extrahepatic bile duct carcinoma
    • Tamada S, Shibahara H, Higashi M, et al. MUC4 is a novel prognostic factor of extrahepatic bile duct carcinoma. Clin Cancer Res 2006;12:4257-64.
    • (2006) Clin Cancer Res , vol.12 , pp. 4257-4264
    • Tamada, S.1    Shibahara, H.2    Higashi, M.3
  • 37
    • 33748633513 scopus 로고    scopus 로고
    • 20(S)-Ginsenoside Rg3 prevents endothelial cell apoptosis via inhibition of a mitochondrial caspase pathway
    • Min JK, Kim JH, Cho YL, et al. 20(S)-Ginsenoside Rg3 prevents endothelial cell apoptosis via inhibition of a mitochondrial caspase pathway. Biochem Biophys Res Commun 2006;349:987-94.
    • (2006) Biochem Biophys Res Commun , vol.349 , pp. 987-994
    • Min, J.K.1    Kim, J.H.2    Cho, Y.L.3
  • 38
    • 5044238876 scopus 로고    scopus 로고
    • Integrin signaling during tumor progression
    • Guo W, Giancotti FG. Integrin signaling during tumor progression. Nat Rev Mol Cell Biol 2004;10:816-26.
    • (2004) Nat Rev Mol Cell Biol , vol.10 , pp. 816-826
    • Guo, W.1    Giancotti, F.G.2
  • 39
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-AKT pathway in human cancer
    • Vivanco I, Sawyers CL. The phosphatidylinositol 3-kinase-AKT pathway in human cancer. Nat Rev Cancer 2002;2:489-501. (Pubitemid 37328931)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.7 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 40
    • 0029941632 scopus 로고    scopus 로고
    • A nonneuronal isoform of cell adhesion molecule L1: Tissue-specific expression and functional analysis
    • Takeda Y, Asou H, Murakami Y, et al. A nonneuronal isoform of cell adhesion molecule L1: tissue-specific expression and functional analysis. J Neurochem 1996;66:2338-49. (Pubitemid 26159068)
    • (1996) Journal of Neurochemistry , vol.66 , Issue.6 , pp. 2338-2349
    • Takeda, Y.1    Asou, H.2    Murakami, Y.3    Miura, M.4    Kobayashi, M.5    Uyemura, K.6
  • 41
    • 21344459308 scopus 로고    scopus 로고
    • The role of chemotherapy in cholangiocarcinoma
    • Thongprasert S. The role of chemotherapy in cholangiocarcinoma. Ann Oncol 2005;16:ii93-6.
    • (2005) Ann Oncol , vol.16
    • Thongprasert, S.1
  • 42
    • 33846558132 scopus 로고    scopus 로고
    • L1-CAM in a membrane-bound or soluble form augments protection from apoptosis in ovarian carcinoma cells
    • DOI 10.1016/j.ygyno.2006.08.038, PII S0090825806006834
    • Stoeck A, Gast D, Sanderson MP, Issa Y, Gutwein P, Altevogt P. L1-CAM in a membrane-bound or soluble form augments protection from apoptosis in ovarian carcinoma cells. Gynecol Oncol 2007;104:461-9. (Pubitemid 46156956)
    • (2007) Gynecologic Oncology , vol.104 , Issue.2 , pp. 461-469
    • Stoeck, A.1    Gast, D.2    Sanderson, M.P.3    Issa, Y.4    Gutwein, P.5    Altevogt, P.6
  • 44
    • 75149178180 scopus 로고    scopus 로고
    • L1-CAM as a target for treatment of cancer with monoclonal antibodies
    • Weidle UH, Eggle DA, Klostermann S. L1-CAM as a target for treatment of cancer with monoclonal antibodies. Anticancer Res 2009;29:4919-32.
    • (2009) Anticancer Res , vol.29 , pp. 4919-4932
    • Weidle, U.H.1    Eggle, D.A.2    Klostermann, S.3
  • 46
    • 33746260069 scopus 로고    scopus 로고
    • Expression profile analysis in multiple human tumors identifies L1 (CD171) as a molecular marker for differential diagnosis and targeted therapy
    • DOI 10.1016/j.humpath.2006.03.014, PII S0046817706001948
    • Huszar M, Moldenhauer G, Gschwend V, et al. Expression profile analysis in multiple human tumors identifies L1 (CD171) as a molecular marker for differentiated diagnosis and targeted therapy. Hum Pathol 2006;37:1000-8. (Pubitemid 44097029)
    • (2006) Human Pathology , vol.37 , Issue.8 , pp. 1000-1008
    • Huszar, M.1    Moldenhauer, G.2    Gschwend, V.3    Ben-Arie, A.4    Altevogt, P.5    Fogel, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.