Treatment with tiludronic acid helps reduce the development of experimental osteoarthritis lesions in dogs with anterior cruciate ligament transection followed by reconstructive surgery: A 1-year study with quantitative magnetic resonance imaging

Journal of Rheumatology

Volumn 38, Issue 1, 2011, Pages 118-128

  Pelletier, Jean Pierre ^a,b,c   Troncy, Éric ^a,d   Bertaim, Thierry ^e   Thibaud, Dominique ^f   Goulet, Anne Christine ^g   Abram, François ^g   Caron, Judith ^h   Boileau, Christelle ^a   D'Anjou, Marc André ⁱ   Moreau, Maxim ^a   Lussier, Bertrand ^a   Martel Pelletier, Johanne ^h  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b Arthritis Division   (United States)

^c NOTRE DAME HOSPITAL   (Canada)

^d Quebec Animal Pharmacology Research Group   (Canada)

^e CEVA SANTÉ ANIMALE   (France)

^f Ceva Animal Health LLC   (United States)

^g INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^h CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

ⁱ Faculty of Veterinary Medicine   (Canada)

Author keywords

Cartilage volume; Experimental osteoarthritis; Quantitative magnetic resonance imaging; Tiludronic acid

Indexed keywords

AGGRECAN; AGGRECANASE 1; BONE MORPHOGENETIC PROTEIN 2; BUPRENORPHINE; COLLAGEN TYPE 2; COLLAGENASE 3; CYTOKINE; FIBROBLAST GROWTH FACTOR 2; INTERSTITIAL COLLAGENASE; OXYMORPHONE; PETHIDINE; PLACEBO; SOMATOMEDIN C; STROMELYSIN; TILUDRONIC ACID; TUMOR NECROSIS FACTOR BETA 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DOG; FEMUR CONDYLE; HISTOPATHOLOGY; KNEE OSTEOARTHRITIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIBIA;

ANIMALS; ANTERIOR CRUCIATE LIGAMENT; BONE DENSITY CONSERVATION AGENTS; CARTILAGE, ARTICULAR; DIPHOSPHONATES; DOGS; HUMANS; MAGNETIC RESONANCE IMAGING; OSTEOARTHRITIS;

EID: 78650854271     PISSN: 0315162X     EISSN: 14992752     Source Type: Journal    
DOI: 10.3899/jrheum.100642     Document Type: Article

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