Widespread dependence of backup NHEJ on growth state: Ramifications for the use of DNA-PK inhibitors

International Journal of Radiation Oncology Biology Physics

Volumn 79, Issue 2, 2011, Pages 540-548

  Singh, Satyendra K ^a   Wu, Wenqi ^a   Zhang, Lihua ^a   Klammer, Holger ^a   Wang, Minli ^a   Iliakis, George ^a  

^a UNIVERSITY OF ESSEN MEDICAL SCHOOL   (Germany)

Author keywords

Cell cycle; DNA Double Strand Breaks (DSB); Growth state; Nonhomologous end joining (NHEJ); Pulsed field gel electrophoresis

Indexed keywords

CELL CYCLE; DNA DOUBLE STRAND BREAKS (DSB); GROWTH STATE; NONHOMOLOGOUS END JOINING; PULSED FIELD GEL ELECTROPHORESIS;

CELL CULTURE; DNA; ELECTROPHORESIS; GELS; GROWTH (MATERIALS); JOINING; REPAIR;

ECOLOGY;

HISTONE H2AX; PROTEIN GAMMA H2AX; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL GROWTH; CELL KILLING; DNA REPAIR; DOUBLE STRANDED DNA BREAK; MOUSE; NONHOMOLOGOUS END JOINING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULSED FIELD GEL ELECTROPHORESIS;

ANDROSTADIENES; ANIMALS; CELL CYCLE; CELL GROWTH PROCESSES; CELL SURVIVAL; CHO CELLS; CRICETINAE; CRICETULUS; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; ELECTROPHORESIS, GEL, PULSED-FIELD; FLUORESCENT ANTIBODY TECHNIQUE; HISTONES; HUMANS; MICE; MUTATION; PROTEIN KINASE INHIBITORS; SPECIES SPECIFICITY; TERMINOLOGY AS TOPIC;

EID: 78650850519     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2010.08.018     Document Type: Article

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