High-resolution magnetic resonance imaging-based biomechanical stress analysis of carotid atheroma: A comparison of single transient ischaemic attack, recurrent transient ischaemic attacks, non-disabling stroke and asymptomatic patient groups

European Journal of Vascular and Endovascular Surgery

Volumn 41, Issue 1, 2011, Pages 83-90

  Sadat, U ^a,b   Teng, Z ^a   Young, V E ^a   Graves, M J ^a   Gaunt, M E ^b   Gillard, J H ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

Atherosclerosis; Biomechanical stresses; Carotid plaque; Magnetic resonance imaging; Stroke; Transient ischaemic attack

Indexed keywords

ADULT; AGED; ARTICLE; ATHEROMA; ATHEROSCLEROTIC PLAQUE; BIOMECHANICS; CAROTID ARTERY DISEASE; CAROTID ATHEROSCLEROSIS; CLINICAL PROTOCOL; CONTRAST ENHANCEMENT; CONTROLLED STUDY; HUMAN; MAGNETIC RESONANCE ANGIOGRAPHY; MAJOR CLINICAL STUDY; MECHANICAL STRESS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RECURRENT DISEASE; STROKE; SYMPTOMATOLOGY; TRANSIENT ISCHEMIC ATTACK;

AGED; AGED, 80 AND OVER; BIOMECHANICS; CAROTID ARTERY, INTERNAL; CAROTID STENOSIS; HUMANS; ISCHEMIC ATTACK, TRANSIENT; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; MODELS, BIOLOGICAL; PLAQUE, ATHEROSCLEROTIC; RECURRENCE; STRESS, MECHANICAL; STROKE;

EID: 78650847824     PISSN: 10785884     EISSN: 15322165     Source Type: Journal    
DOI: 10.1016/j.ejvs.2010.09.006     Document Type: Article

References (47)

1. A.M. Imparato, T.S. Riles, and F. Gorstein The carotid bifurcation plaque: pathologic findings associated with cerebral ischemia Stroke 10 1979 238 245
2. Department of Health National stroke strategy 2007
3. A.R. Naylor Occam's razor: intervene early to prevent more strokes! J Vasc Surg 48 2008 1053 1059
4. P.M. Rothwell, M. Eliasziw, S.A. Gutnikov, A.J. Fox, D.W. Taylor, and M.R. Mayberg Analysis of pooled data from the randomised controlled trials of endarterectomy for symptomatic carotid stenosis Lancet 361 2003 107 116
5. A.R. Naylor Time is brain! Surgeon 5 2007 23 30
6. C. Yuan, L.M. Mitsumori, M.S. Ferguson, N.L. Polissar, D. Echelard, and G. Ortiz In vivo accuracy of multispectral magnetic resonance imaging for identifying lipid-rich necrotic cores and intraplaque hemorrhage in advanced human carotid plaques Circulation 104 2001 2051 2056
7. C. Yuan, S.X. Zhang, N.L. Polissar, D. Echelard, G. Ortiz, and J.W. Davis Identification of fibrous cap rupture with magnetic resonance imaging is highly associated with recent transient ischemic attack or stroke Circulation 105 2002 181 185
8. T. Saam, T.S. Hatsukami, V.L. Yarnykh, C.E. Hayes, H. Underhill, and B. Chu Reader and platform reproducibility for quantitative assessment of carotid atherosclerotic plaque using 1.5t Siemens, Philips, and General Electric scanners J Magn Reson Imaging 26 2007 344 352
9. Z.Y. Li, S. Howarth, R.A. Trivedi, J. U-King-Im, M.J. Graves, and A. Brown Stress analysis of carotid plaque rupture based on in vivo high resolution MRI J Biomech 39 2006 2611 2622
10. D. Tang, C. Yang, J. Zheng, P.K. Woodard, G.A. Sicard, and J.E. Saffitz 3d MRI-based multicomponent fsi models for atherosclerotic plaques Ann Biomed Eng 32 2004 947 960
11. R.J. Lusby, H.I. Machleder, W. Jeans, R. Skidmore, J.P. Woodcock, and P.C. Clifford Vessel wall and blood flow dynamics in arterial disease Philos Trans R Soc Lond B Biol Sci 294 1981 231 239
12. R.J. Lusby, J.P. Woodcock, H.I. Machleder, L.D. Ferrell, W.D. Jeans, and R. Skidmore Transient ischaemic attacks: the static and dynamic morphology of the carotid artery bifurcation Br J Surg 69 Suppl. 1982 S41 S44
13. Ku DN, McCord BN. Mechanical rupture of the atherosclerotic plaque fibrous cap. Proceedings of 1993 ASME Bioengineering Conference, Colorado 1993; 24:324-26.
14. Z.Y. Li, S.P. Howarth, T. Tang, M.J. Graves, I.J. UK, and R.A. Trivedi Structural analysis and magnetic resonance imaging predict plaque vulnerability: a study comparing symptomatic and asymptomatic individuals J Vasc Surg 45 2007 768 775
15. U. Sadat, Z.Y. Li, V.E. Young, M.J. Graves, J.R. Boyle, and E.L. Warburton Finite element analysis of vulnerable atherosclerotic plaques: a comparison of mechanical stresses within carotid plaques of acute and recently symptomatic patients with carotid artery disease J Neurol Neurosurg Psychiatry 2009 286 289
16. U. Sadat, Z. Teng, V.E. Young, S.R. Walsh, Z.Y. Li, and M.J. Graves Association between biomechanical structural stresses and morphological characteristics of atherosclerotic carotid plaques and subsequent ischaemic cerebrovascular events - a longitudinal in vivo MRI-based finite-element study Eur J Vasc Endovasc Surg 40 2010 485 491
17. M. Eliasziw, J. Kennedy, M.D. Hill, A.M. Buchan, and H.J. Barnett Early risk of stroke after a transient ischemic attack in patients with internal carotid artery disease CMAJ 170 2004 1105 1109
18. L.M. Mitsumori, T.S. Hatsukami, M.S. Ferguson, W.S. Kerwin, J. Cai, and C. Yuan In vivo accuracy of multisequence MR imaging for identifying unstable fibrous caps in advanced human carotid plaques J Magn Reson Imaging 17 2003 410 420
19. T. Saam, J. Cai, L. Ma, Y.Q. Cai, M.S. Ferguson, and N.L. Polissar Comparison of symptomatic and asymptomatic atherosclerotic carotid plaque features with in vivo MR imaging Radiology 240 2006 464 472
20. S.P. Howarth, T.Y. Tang, R. Trivedi, R. Weerakkody, J. U-King-Im, and M.E. Gaunt Utility of uspio-enhanced MR imaging to identify inflammation and the fibrous cap: a comparison of symptomatic and asymptomatic individuals Eur J Radiol 2008
21. V.E. Young, A.J. Patterson, U. Sadat, D.J. Bowden, M.J. Graves, and T.Y. Tang Diffusion-weighted magnetic resonance imaging for the detection of lipid-rich necrotic core in carotid atheroma in vivo Neuroradiology 2010
22. U. Sadat, R.A. Weerakkody, D.J. Bowden, V.E. Young, M.J. Graves, and Z.Y. Li Utility of high resolution MR imaging to assess carotid plaque morphology: a comparison of acute symptomatic, recently symptomatic and asymptomatic patients with carotid artery disease Atherosclerosis 2009 434 439
23. C. Yang, D. Tang, C. Yuan, T.S. Hatsukami, J. Zheng, and P.K. Woodard In vivo/ex vivo MRI-based 3d non-Newtonian fsi models for human atherosclerotic plaques compared with fluid/wall-only models Comput Model Eng Sci 19 2007 233 246
24. K.J. Bathe vol. I: aDINA; vol. II: ADINA-F Theory and modeling guide 2002 ADINA R&D, Inc. Watertown, MA
25. D. Tang, Z. Teng, G. Canton, T.S. Hatsukami, L. Dong, and X. Huang Local critical stress correlates better than global maximum stress with plaque morphological features linked to atherosclerotic plaque vulnerability: an in vivo multi-patient study Biomed Eng Online 8 2009 15
26. S. Aglyamov, A. Skovoroda, H. Xie, K. Kim, J. Rubin, and M. O'Donnell Model-based reconstructive elasticity imaging using ultrasound Int J Biomed Imaging 2007 2007 11
27. Z. Teng, G. Canton, C. Yuan, M. Ferguson, C. Yang, and X. Huang 3d Critical plaque wall stress is a better predictor of carotid plaque rupture sites than flow shear stress: an in vivo MRI-based 3d FSI study J Biomech Eng 132 2010 031007
28. Z. Teng, U. Sadat, Z. Li, X. Huang, C. Zhu, and V.E. Young Arterial luminal curvature and fibrous-cap thickness affect critical stress conditions within atherosclerotic plaque: an in vivo MRI-based 2d finite-element study Ann Biomed Eng 2010 [Epub ahead of print]
29. P.D. Richardson, M.J. Davies, and G.V. Born Influence of plaque configuration and stress distribution on fissuring of coronary atherosclerotic plaques Lancet 2 1989 941 944
30. G.C. Cheng, H.M. Loree, R.D. Kamm, M.C. Fishbein, and R.T. Lee Distribution of circumferential stress in ruptured and stable atherosclerotic lesions. A structural analysis with histopathological correlation Circulation 87 1993 1179 1187
31. R.T. Lee, H.M. Loree, G.C. Cheng, E.H. Lieberman, N. Jaramillo, and F.J. Schoen Computational structural analysis based on intravascular ultrasound imaging before in vitro angioplasty: prediction of plaque fracture locations J Am Coll Cardiol 21 1993 777 782
32. J. Ohayon, P. Teppaz, G. Finet, and G. Rioufol In-vivo prediction of human coronary plaque rupture location using intravascular ultrasound and the finite element method Coron Artery Dis 12 2001 655 663
33. J.N. Redgrave, P. Gallagher, J.K. Lovett, and P.M. Rothwell Critical cap thickness and rupture in symptomatic carotid plaques: the Oxford plaque study Stroke 39 2008 1722 1729
34. J.N. Redgrave, J.K. Lovett, P.J. Gallagher, and P.M. Rothwell Histological assessment of 526 symptomatic carotid plaques in relation to the nature and timing of ischemic symptoms: the Oxford plaque study Circulation 113 2006 2320 2328
35. T.Y. Tang, S.P. Howarth, Z.Y. Li, S.R. Miller, M.J. Graves, and I.J.M. UK Correlation of carotid atheromatous plaque inflammation with biomechanical stress: utility of uspio enhanced MR imaging and finite element analysis Atherosclerosis 196 2008 879 887
36. B. Farahmand, G. Bockrath, and J. Glassco Fatigue and fracture mechanics of high risk parts: application of LEFM & FMDM theory 1997 Chapman & Hall New York pp. 13-102
37. A. Versluis, A.J. Bank, and W.H. Douglas Fatigue and plaque rupture in myocardial infarction J Biomech 39 2006 339 347
38. J.H. Rudd, E.A. Warburton, T.D. Fryer, H.A. Jones, J.C. Clark, and N. Antoun Imaging atherosclerotic plaque inflammation with [18f]-fluorodeoxyglucose positron emission tomography Circulation 105 2002 2708 2711
39. A. Arauz, L. Hoyos, M. Zenteno, R. Mendoza, and E. Alexanderson Carotid plaque inflammation detected by 18f-fluorodeoxyglucose-positron emission tomography. Pilot study Clin Neurol Neurosurg 109 2007 409 412
40. P.M. Rothwell, S.A. Gutnikov, and C.P. Warlow Reanalysis of the final results of the European carotid surgery trial Stroke 34 2003 514 523
41. J.A. Ambrose, M.A. Tannenbaum, D. Alexopoulos, C.E. Hjemdahl-Monsen, J. Leavy, and M. Weiss Angiographic progression of coronary artery disease and the development of myocardial infarction J Am Coll Cardiol 12 1988 56 62
42. E. Falk Why do plaques rupture? Circulation 86 1992 III30 42
43. E. Falk, P.K. Shah, and V. Fuster Coronary plaque disruption Circulation 92 1995 657 671
44. H.M. Loree, B.J. Tobias, L.J. Gibson, R.D. Kamm, D.M. Small, and R.T. Lee Mechanical properties of model atherosclerotic lesion lipid pools Arterioscler Thromb 14 1994 230 234
45. T.Y. Tang, S.P. Howarth, S.R. Miller, M.J. Graves, A.J. Patterson, and J. U-King-Im The atheroma (atorvastatin therapy: effects on reduction of macrophage activity) study. Evaluation using ultrasmall superparamagnetic iron oxide-enhanced magnetic resonance imaging in carotid disease J Am Coll Cardiol 53 2009 2039 2050
46. H. Huang, R. Virmani, H. Younis, A.P. Burke, R.D. Kamm, and R.T. Lee The impact of calcification on the biomechanical stability of atherosclerotic plaques Circulation 103 2001 1051 1056
47. R.A. Trivedi, J. U-King-Im, M.J. Graves, J. Horsley, M. Goddard, and P.J. Kirkpatrick Mri-derived measurements of fibrous-cap and lipid-core thickness: the potential for identifying vulnerable carotid plaques in vivo Neuroradiology 46 2004 738 743