Arterial luminal curvature and fibrous-cap thickness affect critical stress conditions within atherosclerotic plaque: An in vivo MRI-based 2D finite-element study

Annals of Biomedical Engineering

Volumn 38, Issue 10, 2010, Pages 3096-3101

  Teng, Zhongzhao ^a   Sadat, Umar ^a   Li, Zhiyong ^a,b   Huang, Xueying ^c   Zhu, Chengcheng ^a   Young, Victoria E ^a   Graves, Martin J ^a   Gillard, Jonathan H ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b SOUTHEAST UNIVERSITY   (China)

^c XIAMEN UNIVERSITY   (China)

Author keywords

Atherosclerosis; Curvature; MRI; Plaque rupture; Stress

Indexed keywords

ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CAP THICKNESS; CRITICAL STRESS; CURVATURE; FINITE-ELEMENT STUDY; HIGH RESOLUTION; IN-VIVO; INTER QUARTILE RANGES; MATERIAL FAILURES; MECHANICAL STRESS; MRI; PLAQUE RUPTURE; SIMULATION STUDIES; STRESS CONDITION;

DISEASES; FINITE ELEMENT METHOD; MAGNETIC RESONANCE; STRESS ANALYSIS;

RISK ASSESSMENT;

AGED; ARTICLE; BLOOD PRESSURE; CAROTID ARTERY; CAROTID ARTERY DISEASE; FEMALE; FINITE ELEMENT ANALYSIS; HUMAN; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; METHODOLOGY; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGICAL STRESS;

AGED; AGED, 80 AND OVER; BLOOD PRESSURE; CAROTID ARTERIES; CAROTID ARTERY DISEASES; FEMALE; FINITE ELEMENT ANALYSIS; HUMANS; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; MIDDLE AGED; STRESS, PHYSIOLOGICAL;

EID: 77956759920     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-010-0078-3     Document Type: Article

References (26)

1. SR Aglyamov AR Skovoroda H Xie K Kim JM Rubin M O'Donnell TW Wakefield D Myers SY Emelianov 2007 Model-based reconstructive elasticity imaging using ultrasound Int. J. Biomed. Imaging 2007 11 10.1155/2007/35830 (Pubitemid 46987943)
2. RW Bock AC Gray-Weale PA Mock, et al. 1993 The natural history of asymptomatic carotid artery disease J. Vasc. Surg. 17 160 169 1:STN:280:DyaK3s7jt1ynsA%3D%3D 10.1067/mva.1993.43142 8421333 discussion 170-171 (Pubitemid 23047065)
3. JJ Boyle 1997 Association of coronary plaque rupture and atherosclerotic inflammation J. Pathol. 181 93 99 1:STN:280:DyaK2s3isFKltQ%3D%3D 10.1002/(SICI)1096-9896(199701)181:1<93::AID-PATH696>3.0.CO;2-H 9072009 (Pubitemid 27099780)
4. JM Cai TS Hatsukami MS Ferguson, et al. 2002 Classification of human carotid atherosclerotic lesions with in vivo multicontrast magnetic resonance imaging Circulation 106 1368 1373 10.1161/01.CIR.0000028591.44554.F9 12221054 (Pubitemid 35013040)
5. R Corti R Hutter JJ Badimon V Fuster 2004 Evolving concepts in the triad of atherosclerosis, inflammation and thrombosis J. Thromb. Thrombolysis. 17 35 44 1:CAS:528:DC%2BD2cXlvF2huro%3D 10.1023/B:THRO.0000036027.39353.70 15277786 (Pubitemid 39069460)
6. S de Putter BJ Wolters MC Rutten, et al. 2007 Patient-specific initial wall stress in abdominal aortic aneurysms with a backward incremental method J. Biomech. 40 1081 1090 10.1016/j.jbiomech.2006.04.019 16822515 (Pubitemid 46349068)
7. E Falk PK Shah V Fuster 1995 Coronary plaque disruption Circulation 92 657 671 1:STN:280:DyaK2MzmtFWlsw%3D%3D 7634481
8. YC Fung 1991 What are the residual stresses doing in our blood vessels? Ann. Biomed. Eng. 19 237 249 1:STN:280:DyaK38%2FislSmsQ%3D%3D 10.1007/BF02584301 1928868
9. X Huang C Yang C Yuan, et al. 2009 Patient-specific artery shrinkage and 3D zero-stress state in multi-component 3D FSI models for carotid atherosclerotic plaques based on in vivo MRI data Mol. Cell. Biomech. 6 121 134 19444328
10. CL Lendon MJ Davies GV Born PD Richardson 1991 Atherosclerotic plaque caps are locally weakened when macrophages density is increased Atherosclerosis 87 87 90 1:STN:280:DyaK3MzjslahtA%3D%3D 10.1016/0021-9150(91)90235-U 1872926
11. CL Lendon MJ Davies PD Richardson GV Born 1993 Testing of small connective tissue specimens for the determination of the mechanical behaviour of atherosclerotic plaques J. Biomed. Eng. 15 27 33 1:STN:280:DyaK3s7isVylsA%3D%3D 10.1016/0141-5425(93)90089-H 8419677
12. ZY Li S Howarth RA Trivedi, et al. 2006 Stress analysis of carotid plaque rupture based on in vivo high resolution MRI J. Biomech. 39 2611 2622 10.1016/j.jbiomech.2005.08.022 16256124 (Pubitemid 44468398)
13. ZY Li T Tang J U-King-Im M Graves M Sutcliffe JH Gillard 2008 Assessment of carotid plaque vulnerability using structural and geometrical determinants Circ. J. 72 1092 1099 10.1253/circj.72.1092 18577817 (Pubitemid 351957074)
14. JN Redgrave P Gallagher JK Lovett PM Rothwell 2008 Critical cap thickness and rupture in symptomatic carotid plaques: the oxford plaque study Stroke 39 1722 1729 10.1161/STROKEAHA.107.507988 18403733
15. PD Richardson MJ Davies GV Born 1989 Influence of plaque configuration and stress distribution on fissuring of coronary atherosclerotic plaques Lancet 2 941 944 1:STN:280:DyaK3c%2FhtlOgtw%3D%3D 10.1016/S0140-6736(89)90953-7 2571862
16. PM Rothwell M Eliasziw SA Gutnikov, et al. 2003 Analysis of pooled data from the randomised controlled trials of endarterectomy for symptomatic carotid stenosis Lancet 361 107 116 1:STN:280:DC%2BD3s%2FisFaltw%3D%3D 10.1016/S0140-6736(03)12228-3 12531577 (Pubitemid 36092014)
17. L Speelman EM Bosboom GW Schurink, et al. 2009 Initial stress and nonlinear material behavior in patient-specific AAA wall stress analysis J. Biomech. 42 1713 1719 1:STN:280:DC%2BD1Mris1WhsA%3D%3D 10.1016/j.jbiomech.2009. 04.020 19447391
18. N Takaya C Yuan B Chu, et al. 2006 Association between carotid plaque characteristics and subsequent ischemic cerebrovascular events: a prospective assessment with MRI-initial results Stroke 37 818 823 10.1161/01.STR.0000204638. 91099.91 16469957 (Pubitemid 43731915)
19. TY Tang SP Howarth ZY Li, et al. 2008 Correlation of carotid atheromatous plaque inflammation with biomechanical stress: utility of USPIO enhanced MR imaging and finite element analysis Atherosclerosis 196 879 887 1:CAS:528:DC%2BD1cXhsVCitrY%3D 10.1016/j.atherosclerosis.2007.02.004 17350023
20. D Tang Z Teng G Canton, et al. 2009 Sites of rupture in human atherosclerotic carotid plaques are associated with high structural stresses: an in vivo MRI-based 3D fluid-structure interaction study Stroke 40 3258 3263 10.1161/STROKEAHA.109.558676 19628799
21. D Tang Z Teng G Canton, et al. 2009 Local critical stress correlates better than global maximum stress with plaque morphological features linked to atherosclerotic plaque vulnerability: an in vivo multi-patient study Biomed. Eng. Online 8 15 1:CAS:528:DC%2BC3cXht1Kit7o%3D 10.1186/1475-925X-8-15 19650901
22. D Tang C Yang J Zheng, et al. 2005 Local maximal stress hypothesis and computational plaque vulnerability index for atherosclerotic plaque assessment Ann. Biomed. Eng. 33 1789 1801 10.1007/s10439-005-8267-1 16389527 (Pubitemid 43037549)
23. RA Trivedi JM U-King-Im MJ Graves, et al. 2004 MRI-derived measurements of fibrous-cap and lipid-core thickness: the potential for identifying vulnerable carotid plaques in vivo Neuroradiology 46 738 743 10.1007/s00234-004-1247-6 15309350 (Pubitemid 39294893)
24. RA Trivedi JM U-King-Im MJ Graves, et al. 2004 Multi-sequence in vivo MRI can quantify fibrous cap and lipid core components in human carotid atherosclerotic plaques Eur. J. Vasc. Endovasc. Surg. 28 207 213 1:STN:280:DC%2BD2czjt1GrsA%3D%3D 15234703
25. JM U-King-Im TY Tang A Patterson, et al. 2008 Characterisation of carotid atheroma in symptomatic and asymptomatic patients using high resolution MRI J. Neurol. Neurosurg. Psychiatry 79 905 912 1:STN:280:DC%2BD1cvmsVeruw%3D%3D 10.1136/jnnp.2007.127969 18187480
26. AC van der Wal AE Becker CM van der Loos PK Das 1994 Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology Circulation 89 36 44 8281670