Risk factors for late onset gram-negative infections: A case-control study

Archives of Disease in Childhood: Fetal and Neonatal Edition

Volumn 96, Issue 1, 2011, Pages

  Samanta, Srabani ^a   Farrer, Kate ^b   Breathnach, Aodhan ^c   Heath, Paul T ^d  

^a ST MARY S HOSPITAL   (United Kingdom)

^b Rosie Maternity Hospital   (United Kingdom)

^c ST GEORGE S HOSPITAL   (United Kingdom)

^d ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; PIPERACILLIN PLUS TAZOBACTAM; VANCOMYCIN;

ARTICLE; ARTIFICIAL VENTILATION; BACTERIUM IDENTIFICATION; BLOOD CULTURE; CASE CONTROL STUDY; CENTRAL VENOUS CATHETERIZATION; DRUG USE; ENTEROBACTER; ESCHERICHIA COLI; FEMALE; GESTATIONAL AGE; GRAM NEGATIVE INFECTION; HUMAN; INCIDENCE; KLEBSIELLA; LATE ONSET GRAM NEGATIVE SEPSIS AND MENINGITIS; MAJOR CLINICAL STUDY; MALE; MENINGITIS; MORTALITY; NECROTIZING ENTEROCOLITIS; NEWBORN; NEWBORN DEATH; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; SEPSIS; TOTAL PARENTERAL NUTRITION; TREATMENT DURATION; UNITED KINGDOM; VERY LOW BIRTH WEIGHT;

AGE OF ONSET; BIRTH WEIGHT; EPIDEMIOLOGIC METHODS; FEMALE; GESTATIONAL AGE; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; INFANT, VERY LOW BIRTH WEIGHT; LONDON; MALE; MENINGITIS, BACTERIAL; PARENTERAL NUTRITION, TOTAL; SEPSIS;

EID: 78650818035     PISSN: 13592998     EISSN: 14682052     Source Type: Journal    
DOI: 10.1136/adc.2009.169540     Document Type: Article

References (31)

1. Stoll BJ, Hansen N, Fanaroff AA, et al. Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network. Pediatrics 2002;110:285-91.
2. Nambiar S, Singh N. Change in epidemiology of health care-associated infections in a neonatal intensive care unit. Pediatr Infect Dis J 2002;21:839-42.
3. Isaacs D, Barfield C, Clothier T, et al. Late-onset infections of infants in neonatal units. J Paediatr Child Health 1996;32:158-61.
4. Stoll BJ, Gordon T, Korones SB, et al. Late-onset sepsis in very low birth weight neonates: a report from the National Institute of Child Health and Human Development Neonatal Research Network. J Pediatr 1996;129:63-71. (Pubitemid 26277248)
5. Isaacs D. A ten year, multicentre study of coagulase negative staphylococcal infections in Australasian neonatal units. Arch Dis Child Fetal Neonatal Ed 2003;88:F89-93.
6. Karlowicz MG, Buescher ES, Surka AE. Fulminant late-onset sepsis in a neonatal intensive care unit, 1988-1997, and the impact of avoiding empiric vancomycin therapy. Pediatrics 2000;106:1387-90.
7. Glasgow TS, Young PC, Wallin J, et al. Association of intrapartum antibiotic exposure and late-onset serious bacterial infections in infants. Pediatrics 2005;116:696-702.
8. Benjamin DK Jr, DeLong ER, Cotten CM, et al. Postconception age and other risk factors associated with mortality following Gram-negative rod bacteremia. J Perinatol 2004;24:169-74.
9. Leigh L, Stoll BJ, Rahman M, et al. Pseudomonas aeruginosa infection in very low birth weight infants: a case-control study. Pediatr Infect Dis J 1995;14:367-71.
10. Bizzarro MJ, Dembry LM, Baltimore RS, et al. Case-control analysis of endemic Serratia marcescens bacteremia in a neonatal intensive care unit. Arch Dis Child Fetal Neonatal Ed 2007;92:F120-6.
11. Gordon A, Isaacs D. Late onset neonatal Gram-negative bacillary infection in Australia and New Zealand: 1992-2002. Pediatr Infect Dis J 2006;25:25-9.
12. Graham PL 3rd, Begg MD, Larson E, et al. Risk factors for late onset gram-negative sepsis in low birth weight infants hospitalized in the neonatal intensive care unit. Pediatr Infect Dis J 2006;25:113-17. (Pubitemid 43208563)
13. Edwards RK, Locksmith GJ, Duff P. Expanded-spectrum antibiotics with preterm premature rupture of membranes. Obstet Gynecol 2000;96:60-4. (Pubitemid 30336281)
14. Stoll BJ, Hansen N, Fanaroff AA, et al. Changes in pathogens causing early-onset sepsis in very-low-birth-weight infants. N Engl J Med 2002;347:240-7.
15. Shah SS, Ehrenkranz RA, Gallagher PG. Increasing incidence of gram-negative rod bacteremia in a newborn intensive care unit. Pediatr Infect Dis J 1999;18:591-5.
16. Moore MR, Schrag SJ, Schuchat A. Effects of intrapartum antimicrobial prophylaxis for prevention of group-B-streptococcal disease on the incidence and ecology of early-onset neonatal sepsis. Lancet Infect Dis 2003;3:201-13. (Pubitemid 36389183)
17. Levine EM, Ghai V, Barton JJ, et al. Intrapartum antibiotic prophylaxis increases the incidence of gram-negative neonatal sepsis. Infect Dis Obstet Gynecol 1999;7:210-13. (Pubitemid 29379197)
18. Cordero L, Rau R, Taylor D, et al. Enteric gram-negative bacilli bloodstream infections: 17 years' experience in a neonatal intensive care unit. Am J Infect Control 2004;32:189-95. (Pubitemid 38857890)
19. Daley AJ, Isaacs D. Ten-year study on the effect of intrapartum antibiotic prophylaxis on early onset group B streptococcal and Escherichia coli neonatal sepsis in Australasia. Pediatr Infect Dis J 2004;23:630-4. (Pubitemid 38924887)
20. Vermillion ST, Soper DE, Newman RB. Neonatal sepsis and death after multiple courses of antenatal betamethasone therapy. Am J Obstet Gynecol 2000;183:810-14.
21. Roilides E, Kyriakides G, Kadiltsoglou I, et al. Septicemia due to multiresistant Klebsiella pneumoniae in a neonatal unit: a case-control study. Am J Perinatol 2000;17:35-9. (Pubitemid 30452037)
22. van der Zwet WC, Kaiser AM, van Elburg RM, et al. Nosocomial infections in a Dutch neonatal intensive care unit: surveillance study with definitions for infection specifically adapted for neonates. J Hosp Infect 2005;61:300-11.
23. Singh N, Patel KM, Léger MM, et al. Risk of resistant infections with Enterobacteriaceae in hospitalized neonates. Pediatr Infect Dis J 2002;21:1029-33.
24. Martins IS, Pessoa-Silva CL, Nouer SA, et al. Endemic extended-spectrum betalactamase-producing Klebsiella pneumoniae at an intensive care unit: risk factors for colonization and infection. Microb Drug Resist 2006;12:50-8.
25. Flidel-Rimon O, Friedman S, Lev E, et al. Early enteral feeding and nosocomial sepsis in very low birthweight infants. Arch Dis Child Fetal Neonatal Ed 2004;89:F289-92.
26. Rønnestad A, Abrahamsen TG, Medbø S, et al. Late-onset septicemia in a Norwegian national cohort of extremely premature infants receiving very early full human milk feeding. Pediatrics 2005;115:e269-76.
27. Pierro A, van Saene HK, Donnell SC, et al. Microbial translocation in neonates and infants receiving long-term parenteral nutrition. Arch Surg 1996;131:176-9.
28. Alaedeen DI, Walsh MC, Chwals WJ. Total parenteral nutrition-associated hyperglycemia correlates with prolonged mechanical ventilation and hospital stay in septic infants. J Pediatr Surg 2006;41:239-44; discussion 239-44.
29. Kalhan SC, Oliven A, King KC, et al. Role of glucose in the regulation of endogenous glucose production in the human newborn. Pediatr Res 1986;20:49-52.
30. Donmoyer CM, Chen SS, Lacy DB, et al. Infection impairs insulin-dependent hepatic glucose uptake during total parenteral nutrition. Am J Physiol Endocrinol Metab 2003;284:E574-82.
31. Van den Berghe G. How does blood glucose control with insulin save lives in intensive care? J Clin Invest 2004;114:1187-95.