Synthesis and evaluation of β-carboline derivatives as potential monoamine oxidase inhibitors

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 1, 2011, Pages 134-144

  Reniers, J ^a   Robert, S ^a   Frederick, R ^a   Masereel, B ^a   Vincent, S ^a   Wouters, J ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

Author keywords

Carboline; Docking; MAO inhibition; X ray

Indexed keywords

7 (2 HYDROXYETHYLOXY) 1 METHYL BETA CARBOLINE; 7 (2 METHOXYETHOXY) 1 METHYL BETA CARBOLINE; 7 (4,4,4 TRIFLUOROBUTOXY) 1 METHYL BETA CARBOLINE; 7 (ALLYLOXY) 1 METHYL BETA CARBOLINE; 7 (BENZYLOXY) 1 METHYL BETA CARBOLINE; 7 (CYCLOHEXYLMETHOXY) 1 METHYL BETA CARBOLINE; 7 (ETHYLOXYMORPHOLINE) 1 METHYL BETA CARBOLINE; 7 (ISOBUTYLOXY) 1 METHYL BETA CARBOLINE; 7 (N,N DIMETHYLAMINOETHYLOXY) 1 METHYL BETA CARBOLINE; 7 (N,N DIMETHYLAMINOPROPYLOXY) 1 METHYL BETA CARBOLINE; 7 (NAPHTHALEN 2 YLMETHOXY) 1 METHYL BETA CARBOLINE; 7 (PHENETHOXY) 1 METHYL BETA CARBOLINE; 7 (PYRIDIN 2 YLMETHOXY) 1 METHYL BETA CARBOLINE; 7 (PYRIDIN 3 YLMETHOXY) 1 METHYL BETA CARBOLINE; 7 (PYRIDIN 4 YLMETHOXY) 1 METHYL BETA CARBOLINE; HARMINE; MONOAMINE OXIDASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HYDROPHOBICITY; LIPOPHILICITY; MOLECULAR DOCKING; STRUCTURE ACTIVITY RELATION;

CARBOLINES; CRYSTALLOGRAPHY, X-RAY; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS;

EID: 78650757792     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.11.041     Document Type: Article

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