Synthesis and in vitro anti-hepatitis B virus activity of six-membered azanucleoside analogues

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 1, 2011, Pages 41-51

  Wang, Dan ^a   Li, Yu Huan ^b   Wang, Yu Ping ^b   Gao, Rong Mei ^b   Zhang, Li He ^a   Ye, Xin Shan ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

Anti viral agent; Azanucleoside; Azasugar; Hepatitis B virus; Synthesis

Indexed keywords

1 (TERT BUTOXYCARBONYL) 2 (5 FLUORO URACIL 1 YL) PIPERIDINE 3,4,5 TRIYL TRIACETATE; 1 (TERT BUTOXYCARBONYL)PIPERIDINE 2,3,4,5 TETRAYL TETRAACETATE; 2 (4 ACETAMIDO CYTOSINE 1 YL) 1 (TERTBUTOXYCARBONYL)PIPERIDINE 3,4,5 TRIYL TRIACETATE; 2 (N 6 BENZOYL ADENINE 9 YL) 1 (TERTBUTOXYCARBONYL)PIPERIDINE 3,4,5 TRIYL TRIACETATE; 3,4,5 TRIS(BENZYLOXY) 1 (4 METHOXYBENZYL)PIPERIDIN 2 ONE; ANTIVIRUS AGENT; LACTONE DERIVATIVE; LAMIVUDINE; LEWIS ACID; MONOSACCHARIDE; NUCLEIC ACID BASE; NUCLEOSIDE DERIVATIVE; TERT BUTYL 2 (5 FLUORO URACIL 1 YL) 3,4,5 TRIHYDROXYPIPERIDINE 1 CARBOXYLATE; TERT BUTYL 2 (5 FLUORO URACIL YL) 3,4,5 TRIHYDROXYPIPERIDINE 1 CARBOXYLATE; TERT BUTYL 2 (ADENINE 9 YL) 3,4,5 TRIHYDROXYPIPERIDINE 1 CARBOXYLATE; TERT BUTYL 2 (CYTOSINE 1 YL) 3,4,5 TRIHYDROXYIPERIDINE 1 CARBOXYLATE; TERT BUTYL 2 (URACIL 1 YL) 3,4,5 TRIHYDROXYPIPERIDINE 1 CARBOXYLATE; TERT BUTYL 2 ACETOXY 3,4,5 TRIS(BENZYLOXY)PIPERIDINE 1 CARBOXYLATE; TERT BUTYL 3,4,5 TRIHYDROXY 2 (THYMIDINE 1 YL)PIPERIDINE 1 CARBOXYLATE; TERT BUTYL 3,4,5 TRIHYDROXY 2 (THYMINE 1 YL)PIPERIDINE 1 CARBOXYLATE; TERT BUTYL 3,4,5 TRIHYDROXY 2 OXOPIPERIDINE 1 CARBOXYLATE; TERT BUTYL 3,4,5 TRIS(BENZYLOXY) 2 (THYMIDINE 1 YL)PIPERIDINE 1 CARBOXYLATE; TERT BUTYL 3,4,5 TRIS(BENZYLOXY) 2 (THYMINE 1 YL)PIPERIDINE 1 CARBOXYLATE; TERT BUTYL 3,4,5 TRIS(BENZYLOXY) 2 OXOPIPERIDINE 1 CARBOXYLATE; UNCLASSIFIED DRUG;

ACETYLATION; ANTIHEPATITIS ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYST; CELL STRAIN HEPG2; CHEMICAL REACTION; CYTOTOXICITY; DRUG ACTIVITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HEPATITIS B VIRUS; HEPATOBLASTOMA; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTIVIRAL AGENTS; AZA COMPOUNDS; CELL LINE, TUMOR; HEPATITIS B VIRUS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; NUCLEOSIDES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

HEPATITIS B VIRUS;

EID: 78650756953     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.11.063     Document Type: Article

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