Probucol attenuates cyclophosphamideinduced oxidative apoptosis, p53 and Bax signal expression in rat cardiac tissues

Oxidative Medicine and Cellular Longevity

Volumn 3, Issue 5, 2010, Pages 308-316

  Asiri, Yousif A ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Apoptosis; ATP; Cyclophosphamide; Oxidative stress; Probucol

Indexed keywords

ANTIOXIDANT ENZYME; ANTIOXIDANT PROPERTIES; ANTIOXIDANT SYSTEMS; APOPTOSIS; APOPTOTIC GENES; ATP; CANCER CHEMOTHERAPY; CARDIAC ENZYMES; CARDIAC TISSUES; CARDIOTOXICITY; CONTROL GROUPS; CORN OIL; CYCLOPHOSPHAMIDE; DNA DAMAGES; DOWN-REGULATION; DOXORUBICIN; ENERGY PRODUCTIONS; GLUTATHIONE PEROXIDASE; GLUTATHIONES; INTRAPERITONEALLY; LACTATE DEHYDROGENASE; LIPID PEROXIDATION; MITOCHONDRIAL OXIDATIVE PHOSPHORYLATION; MRNA EXPRESSION; MRNA EXPRESSION LEVEL; POTENTIAL INHIBITORS; PRE-TREATMENT; PROBUCOL; PROTECTIVE EFFECTS; REAL-TIME PCR; SINGLE-DOSE; SUPER OXIDE DISMUTASE; TOXIC METABOLITES; TREATMENT GROUP;

ACETONE; ADENOSINETRIPHOSPHATE; ANIMALS; CATALYSTS; CELL DEATH; CHEMOTHERAPY; CHOLESTEROL; ENZYMES; HEART; HISTOLOGY; OXIDATIVE STRESS; OXYGEN; PHENOLS; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; RATS; TISSUE; TOXICITY; VEGETABLE OILS;

GENE EXPRESSION;

ADENOSINE TRIPHOSPHATE; CATALASE; CHOLESTEROL ESTER; CORN OIL; CREATINE KINASE ISOENZYME; CYCLOPHOSPHAMIDE; GLUTATHIONE PEROXIDASE; LACTATE DEHYDROGENASE; MESSENGER RNA; PROBUCOL; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; CHOLESTEROL; CREATINE KINASE; HYPOCHOLESTEROLEMIC AGENT; OXIDOREDUCTASE; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIOTOXICITY; CONTROLLED STUDY; CYCLOPHOSPHAMIDE INDUCED OXIDATIVE APOPTOSIS; DOWN REGULATION; GENE EXPRESSION; HEART; HEART FAILURE; HEART PROTECTION; LIPID PEROXIDATION; MALE; NONHUMAN; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; ANIMAL; BLOOD; CHEMICALLY INDUCED DISORDER; GENETICS; HEART DISEASE; HEART MUSCLE; METABOLISM; OXIDATIVE STRESS; WISTAR RAT;

ANIMALIA; RATTUS; ZEA MAYS;

ANIMALS; ANTICHOLESTEREMIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CHOLESTEROL; CREATINE KINASE; CYCLOPHOSPHAMIDE; HEART DISEASES; LACTATE DEHYDROGENASES; MALE; MYOCARDIUM; OXIDATIVE STRESS; OXIDOREDUCTASES; PROBUCOL; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TRIGLYCERIDES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 78650750982     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.4161/oxim.3.5.13107     Document Type: Article

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