Effect of dl-α-lipoic acid on cyclophosphamide induced lysosomal changes in oxidative cardiotoxicity

Life Sciences

Volumn 80, Issue 21, 2007, Pages 1993-1998

  Mythili, Y ^a   Sudharsan, P T ^a   Amudha, G ^a   Varalakshmi, P ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Cyclophosphamide; Heart; Lipoic acid; Lysosomal enzymes

Indexed keywords

8 HYDROXY 2 DEOXYGUANOSINE; ACID PHOSPHATASE; BETA GALACTOSIDASE; BETA GLUCURONIDASE; CARBONYL DERIVATIVE; CATHEPSIN D; CYCLOPHOSPHAMIDE; GUANOSINE DERIVATIVE; THIOCTIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOTOXICITY; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HEART PROTECTION; LYSOSOME; MALE; NONHUMAN; RAT; TREATMENT DURATION; WISTAR RAT;

ANALYSIS OF VARIANCE; ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOPHOSPHAMIDE; DEOXYGUANOSINE; HEART; HYDROXYPROLINE; MALE; MYOCARDIUM; OXIDATIVE STRESS; PROTECTIVE AGENTS; PROTEIN CARBONYLATION; RATS; THIOCTIC ACID;

RATTUS;

EID: 34247141068     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.02.040     Document Type: Article

References (44)

1. Arnheim N., and Cortopassi G. Deleterious mitochondrial DNA mutations accumulate in aging human tissues. Mutation Research 275 3-6 (1992) 157-167
2. Brunk U.T., Neuzil J., and Eaton J.W. Lysosomal involvement in apoptosis. Redox Report 6 (2001) 91-97
3. Cordis G.A., Maulik G., Bagchi D., Riedel W., and Das D.K. Detection of oxidative DNA damage to ischemic reperfused rat hearts by 8-hydroxydeoxyguanosine formation. Journal of Molecular and Cellular Cardiology 30 10 (1998) 1939-1944
4. Davies K.J.A. Proteolytic systems as secondary antioxidant defenses. In: Chow C.K. (Ed). Cellular Antioxidant Defense Mechanisms vol. 2 (1988), CRC Press, Boca Raton, Florida 25
5. Decker R.S., and Wildenthal K. Role of lysosomes and latent hydrolytic enzymes in ischemic damage and repair of the heart. In: Wlldenthal K. (Ed). Degradative Processes in Heart and Skeletal Muscle (1980), Elsevier/North Holland Biomedical Press, Amsterdam 389-418
6. Dizdaroglu M. Chemical determination of free radical-induced damage to DNA. Free Radical Biology & Medicine 10 3-4 (1991) 225-242
7. Dollery C. Cyclophosphamide. In: Dollery C. (Ed). Therapeutic Drugs (1999), Churchill Livingstone, Edinburg 349-353
8. Estrada D.E., Ewart H.S., Tsakiridis T., Volchuk A., Ramlal T., Tritschler H., and Klip A. Stimulation of glucose uptake by the natural coenzyme alpha-lipoic acid/thioctic acid: participation of elements of the insulin signaling pathway. Diabetes 45 12 (1996) 1798-1804
9. Etherington D.J. The nature of the collagenolytic cathepsin of rat liver and its distribution in other rat tissues. Biochemical Journal 127 4 (1972) 685-692
10. Floyd R.A., and Schneider J.E. Hydroxy free radical damage to DNA. In: Vigo-Pelfrey C. (Ed). Membrane Lipid Oxidation (1990), CRC Press, Boca Raton, Florida 1
11. Freisleben H.J. Lipoic acid reduces ischemia-reperfusion injury in animal models. Toxicology 148 2-3 (2000) 159-171
12. Frohlich E.D. Fibrosis and ischemia: the real risks in hypertensive heart disease. American Journal of Hypertension 14 6 Pt 2 (2001) 194S-199S
13. Ge J., Zhao G., Chen R., Li S., Wang S., Zhang X., Zhuang Y., Du J., Yu X., Li G., and Yang Y. Enhanced myocardial cathepsin B expression in patients with dilated cardiomyopathy. European Journal of Heart Failure 8 3 (2006) 284-289
14. Giri S.N., Blaisdell R., Rucker R.B., Wang Q., and Hyde D.M. Amelioration of bleomycin-induced lung fibrosis in hamsters by dietary supplementation with taurine and niacin: biochemical mechanisms. Environmental Health Perspectives 102 Suppl 10 (1994) 137-147
15. Hopkins H.A., Betsill Jr. W.L., Hobson A.S., and Looney W.B. Cyclophosphamide-induced cardiomyopathy in the rat. Cancer Treatment Reports 66 7 (1982) 1521-1527
16. Ito K., Inoue S., Yamamoto K., and Kawanishi S. 8-Hydroxydeoxyguanosine formation at the 5′ site of 5′-GG-3′ sequences in double-stranded DNA by UV radiation with riboflavin. Journal of Biological Chemistry 268 18 (1993) 13221-13227
17. Kagan V.E., Shvedova A., Serbinova E., Khan S., Swanson C., Powell R., and Packer L. Dihydrolipoic acid-a universal antioxidant both in the membrane and in the aqueous phase. Reduction of peroxyl, ascorbyl and chromanoxyl radicals. Biochemical Pharmacology 44 8 (1992) 1637-1649
18. Kalra J., and Prasad K. Oxygen free radicals and cardiac depression. Clinical Biochemistry 27 3 (1994) 163-168
19. Kawai Y., and Anno K. Mucopolysaccharide-degrading enzymes from the liver of the squid, Ommastrephes sloani pacificus. I. Hyaluronidase. Biochimica et Biophysica Acta 242 2 (1971) 428-436
20. King L. The hydrolases - acid and alkaline phosphatases. In: Van D. (Ed). Practical Clinical Enzymology (1965), Nostrand Company Limited, London 191-208
21. Lee C.K., Harman G.S., Hohl R.J., and Gingrich R.D. Fatal cyclophosphamide cardiomyopathy: its clinical course and treatment. Bone Marrow Transplantation 18 3 (1996) 573-577
22. Levine R.L., Garland D., Oliver C.N., Amici A., Climent I., Lenz A.G., Ahn B.W., Shaltiel S., and Stadtman E.R. Determination of carbonyl content in oxidatively modified proteins. Methods in Enzymology 186 (1990) 464-478
23. Lopez-Burillo S., Tan D.X., Mayo J.C., Sainz R.M., Manchester L.C., and Reiter R.J. Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and alpha-lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents: a study of their individual and synergistic actions. Journal of Pineal Research 34 4 (2003) 69-77
24. Maruhn D. Rapid colorimetric assay of beta-galactosidase and N-acetyl-beta-glucosaminidase in human urine. Clinica Chimica Acta 73 3 (1976) 453-461
25. Mathew S., Menon P.V., and Kurup P.A. Changes in glycoproteins in isoproterenol-induced myocardial infarction in rats. Indian Journal of Biochemistry and Biophysics 19 1 (1982) 41-43
26. 2+-dependent ATPase-activity in left ventricular myocardium during mechanical circulatory support. Journal of Heart and Lung Transplantation 22 11 (2003) 1209-1216
27. Morandi P., Ruffini P.A., Benvenuto G.M., Raimondi R., and Fosser V. Cardiac toxicity of high-dose chemotherapy. Bone Marrow Transplantation 35 4 (2005) 323-334
28. Mythili Y., Sudharsan P.T., and Selvakumar E. Protective effect of dl-α-lipoic acid on cyclophosphamide induced oxidative cardiac injury. Chemico-Biological Interactions 151 1 (2004) 13-19
29. Mythili Y., Sudharsan P.T., and Varalakshmi P. Cytoprotective role of dl-alpha-lipoic acid in cyclophosphamide induced myocardial toxicity. Molecular and Cellular Biochemistry 276 1-2 (2005) 39-44
30. Nohl H., and Hegner D. Do mitochondria produce oxygen radicals in vivo?. European Journal of Biochemistry 82 2 (1978) 563-567
31. Packer L., Witt E.H., and Tritschler H.J. Alpha-Lipoic acid as a biological antioxidant. Free Radical Biology & Medicine 19 2 (1995) 227-250
32. Persson H.L., Yu Z., Tirosh O., Eaton J.W., and Brunk U.T. Prevention of oxidant-induced cell death by lysosomotropic iron chelators. Free Radical Biology & Medicine 34 10 (2003) 1295-1305
33. Ravens K.G., and Gudbjarnason S. Changes in the activities of lysosomal enzymes in infarcted canine heart muscle. Circulation Research 24 6 (1969) 851-856
34. Ricciutti M.A. Myocardial lysosome stability in the early stages of acute ischemic injury. American Journal of Cardiology 30 5 (1972) 492-497
35. Saada A., Bar-Meir M., Belaiche C., Miller C., and Elpeleg O. Evaluation of enzymatic assays and compounds affecting ATP production in mitochondrial respiratory chain complex I deficiency. Analytical Biochemistry 335 1 (2004) 66-72
36. Senthilkumar S., Devaki T., Manohar B.M., and Babu M.S. Effect of squalene on cyclophosphamide-induced toxicity. Clinica Chimica Acta 364 1-2 (2006) 335-342
37. Sohal R.S., and Brunk U.T. Mitochondrial production of pro-oxidants and cellular senescence. Mutatation Research 275 3-6 (1992) 295-304
38. Tagesson C., Kallberg M., Klintenberg C., and Starkhammar H. Determination of urinary 8-hydroxydeoxyguanosine by automated coupled-column high performance liquid chromatography: a powerful technique for assaying in vivo oxidative DNA damage in cancer patients. European Journal of Cancer 31A 6 (1995) 934-940
39. Takahashi S., Barry A.C., and Factor S.M. Collagen degradation in ischaemic rat hearts. Biochemical Journal 265 1 (1990) 233-241
40. Venkatesan N., Punithavathi D., and Chandrakasan G. Biochemical and connective tissue changes in cyclophosphamide-induced lung fibrosis in rats. Biochemical Pharmacology 56 7 (1998) 895-904
41. Woessner Jr. J.F. The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Archives of Biochemistry and Biophysics 93 (1961) 440-447
42. Yamamoto S., Sawada K., Shimomura H., Kawamura K., and James T.N. On the nature of cell death during remodeling of hypertrophied human myocardium. Journal of Molecular and Cellular Cardiology 32 1 (2000) 161-175
43. Zak R., Martin A.F., Reddy M.K., and Rabinowitz M. Control of protein balance in hypertrophied cardiac muscle. Circulation Research 38 5 Suppl 1 (1976) I145
44. Ziori C.H.C., Zioris T.H.C., and Kyriakidis M.K. Apoptosis in heart failure. Hellenic Journal of Cardiology 44 (2003) 56-70