Cytotoxicity and topoisomerase I/II inhibition of glycosylated 2-phenyl-indoles, 2-phenyl-benzo[b]thiophenes and 2-phenyl-benzo[b]furans

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 1, 2011, Pages 603-612

  Shi, Wei ^a   Marcus, Sandra L ^a   Lowary, Todd L ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Anthracycline; Cytotoxicity; Functional mimetics; Topoisomerase inhibition

Indexed keywords

ANTHRACYCLINE DERIVATIVE; DAUNORUBICIN; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; FURAN DERIVATIVE; INDOLE DERIVATIVE; THIOPHENE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CELL STRAIN HEPG2; CELL STRAIN MCF 7; CELL VIABILITY; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA BINDING; DRUG CYTOTOXICITY; DRUG SCREENING; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; NONHUMAN;

BENZOFURANS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; GLYCOSYLATION; HUMANS; INDOLES; INHIBITORY CONCENTRATION 50; THIOPHENES; TOPOISOMERASE I INHIBITORS; TOPOISOMERASE II INHIBITORS;

EID: 78650723189     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.10.054     Document Type: Article

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