Influence of PEGylation with linear and branched PEG chains on the adsorption of glucagon to hydrophobic surfaces

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 77, Issue 1, 2011, Pages 139-147

  Pinholt, Charlotte ^a   Bukrinsky, Jens Thostrup ^b   Hostrup, Susanne ^b   Frokjaer, Sven ^a   Norde, Willem ^c,d   Jorgensen, Lene ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NOVO NORDISK A S   (Denmark)

^c WAGENINGEN UNIVERSITY   (Netherlands)

^d UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Fixed angle optical reflectometry; Glucagon; Isothermal titration calorimetry; PEGylation; Protein adsorption; Total internal reflection fluorescence

Indexed keywords

GLUCAGON; MACROGOL;

ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG RELEASE; FLUORESCENCE ANALYSIS; HYDROPHOBICITY; ISOTHERMAL TITRATION CALORIMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; REFLECTOMETRY;

ADSORPTION; GLUCAGON; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KINETICS; MOLECULAR WEIGHT; POLYETHYLENE GLYCOLS; POLYMERS; POLYSTYRENES; PROTEIN CONFORMATION; SILANES; SURFACE PROPERTIES;

EID: 78650701603     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.11.001     Document Type: Article

References (44)

1. F.M. Veronese, and A. Mero The impact of PEGylation on biological therapies Biodrugs 22 2008 315 329
2. M. Hamidi, A. Azadi, and P. Rafiei Pharmacokinetic consequences of pegylation Drug Delivery 13 2006 399 409
3. T. Yamaoka, Y. Tabata, and Y. Ikada Distribution and tissue uptake of poly(ethylene glycol) with different molecular-weights after intravenous administration to mice Journal of Pharmaceutical Sciences 83 1994 601 606
4. A. Abuchowski, J.R. Mccoy, N.C. Palczuk, T. Vanes, and F.F. Davis Effect of covalent attachment of polyethylene-glycol on immunogenicity and circulating life of bovine liver catalase Journal of Biological Chemistry 252 1977 3582 3586
5. C. Delgado, G.E. Francis, and D. Fisher The uses and properties of peg-linked proteins Critical Reviews in Therapeutic Drug Carrier Systems 9 1992 249 304
6. F.M. Veronese Peptide and protein PEGylation: a review of problems and solutions Biomaterials 22 2001 405 417
7. J.S. Kang, P.P. Deluca, and K.C. Lee Emerging PEGylated drugs Expert Opinion on Emerging Drugs 14 2009 363 380
8. C. Monfardini, O. Schiavon, P. Caliceti, M. Morpurgo, J.M. Harris, F.M. Veronese, and A. Branched Monomethoxypoly(ethylene glycol) for protein modification Bioconjugate Chemistry 6 1995 62 69
9. F.M. Veronese, P. Caliceti, and O. Schiavon Branched and linear poly(ethylene glycol): influence of the polymer structure on enzymological, pharmacokinetic, and immunological properties of protein conjugates Journal of Bioactive and Compatible Polymers 12 1997 196 207
10. R. Bhat, and S.N. Timasheff Steric exclusion is the principal source of the preferential hydration of proteins in the presence of polyethylene glycols Protein Science 1 1992 1133 1143
11. J.C. Lee, and L.L.Y. Lee Preferential solvent interactions between proteins and polyethylene glycols Journal of Biological Chemistry 256 1981 625 631
12. D.I. Svergun, F. Ekstrom, K.D. Vandegriff, A. Malavalli, D.A. Baker, C. Nilsson, and R.M. Winslow Solution structure of poly(ethylene) glycol-conjugated hemoglobin revealed by small-angle x-ray scattering: implications for a new oxygen therapeutic Biophysical Journal 94 2008 173 181
13. Y.L. Lu, S.E. Harding, A. Turner, B. Smith, D.S. Athwal, J.G. Grossmann, K.G. Davis, and A.J. Rowe Effect of PEGylation on the solution conformation of antibody fragments Journal of Pharmaceutical Sciences 97 2008 2062 2079
14. S.M. Daly, T.M. Przybycien, and R.D. Tilton Adsorption of poly(ethylene glycol)-modified ribonuclease A to a poly(lactide-co-glycolide) surface Biotechnology and Bioengineering 90 2005 856 868
15. S.M. Daly, T.M. Przybycien, and R.D. Tilton Adsorption of poly(ethylene glycol)-modified lysozyme to silica Langmuir 21 2005 1328 1337
16. S.M. Daly, T.M. Przybycien, and R.D. Tilton Aggregation of lysozyme and of poly(ethylene glycol)-modified lysozyme after adsorption to silica Colloids and Surfaces B - Biointerfaces 57 2007 81 88
17. P. Stigsnaes, S. Frokjaer, S. Bjerregaard, M. Van de Weert, P. Kingshott, and E.H. Moeller Characterisation and physical stability of PEGylated glucagon International Journal of Pharmaceutics 330 2007 89 98 Ref Type: Journal (Full
18. P. Stigsnaes, Pharmaceutical Aspects of PEGylated Glucagon, Ref Type: Thesis/Dissertation, 2007.
19. J.H. Maas, M.A.C. Stuart, A.B. Sieval, H. Zuilhof, and E.J.R. Sudholter Preparation of polystyrene brushes by reaction of terminal vinyl groups on silicon and silica surfaces Thin Solid Films 426 2003 135 139
20. 2 surfaces by means of ellipsometry, using different ambient media Journal of Physical Chemistry 97 1993 1656 1660
21. S.H. Mollmann, J.T. Bukrinsky, S. Frokjaer, and U. Elofsson Adsorption of human insulin and Asp(B28) insulin on a PTFE-like surface Journal of Colloid and Interface Science 286 2005 28 35
22. C. Pinholt, M. Fanø, C. Wiberg, S. Hostrup, J.T. Bukrinsky, S. Frokjaer, W. Norde, and L. Jorgensen Influence of glycosylation on the adsorption of thermomyces lanuginosus lipase to hydrophobic and hydrophilic surfaces European Journal of Pharmaceutical Sciences 40 2010 273 281
23. J.C. Dijt, M.A.C. Stuart, J.E. Hofman, and G.J. Fleer Kinetics of polymer adsorption in stagnation point flow Colloids and Surfaces 51 1990 141 158
24. M.B. Huglin Specific refractive index increments of polymer solutions. Part I. Literature values Journal of Applied Polymer Science 9 1965 3963 4001
25. B.K. Lok, Y.L. Cheng, and C.R. Robertson Total internal-reflection fluorescence - a technique for examining interactions of macromolecules with solid-surfaces 1 Journal of Colloid and Interface Science 91 1983 87 103
26. C.M. Roth, and A.M. Lenhoff Electrostatic and Van-Der-Waals contributions to protein adsorption - comparison of theory and experiment Langmuir 11 1995 3500 3509
27. V. Hlady, R.A. Vanwagenen, and J.D. Andrade Total internal reflection intrinsic fluorescence (TIRIF) spectroscopy applied to protein adsorption J.D. Andrade, Surface and Interfacial Aspects of Biomedical Polymers 1985 Plenum Press New York 81 119
28. J. Thomsen, K. Kristiansen, K. Brunfeldt, and F. Sundby Amino-acid sequence of human glucagon Febs Letters 21 1972 315 319
29. B. Panijpan, and W.B. Gratzer Conformational nature of monomeric glucagon European Journal of Biochemistry 45 1974 547 553
30. P.A. Srere, and G.C. Brooks Circular dichroism of glucagon solutions Archives of Biochemistry and Biophysics 129 1969 708 710
31. C. Toniolo, F. Formaggio, S. Tognon, Q.B. Broxterman, B. Kaptein, R. Huang, V. Setnicka, T.A. Keiderling, I.H. Mccoll, L. Hecht, and L.D. Barron The complete chirospectroscopic signature of the peptide 3(10)-helix in aqueous solution Biopolymers 75 2004 32 45
32. C. Tanford The Hydrophobic Effect: Formation of Micelles and Biological Membranes 1973 John Wiley & Sons New York
33. J.J. Ramsden Puzzles and paradoxes in protein adsorption Chemical Society Reviews 24 1995 73 78
34. C.A. Haynes, and W. Norde Globular proteins at solid/liquid interfaces Colloids and Surfaces B - Biointerfaces 2 1994 517 566
35. E. Gasteiger, A. Gattiker, C. Hoogland, I. Ivanyi, R.D. Appel, and A. Bairoch ExPASy: the proteomics server for in-depth protein knowledge and analysis Nucleic Acids Research 31 2003 3784 3788
36. C.J. Fee Size comparison between proteins PEGylated with branched and linear Poly(Ethylene glycol) molecules Biotechnology and Bioengineering 98 2007 725 731
37. M. Kusterle, S. Jevsevar, and V.G. Porekar Size of pegylated protein conjugates studied by various methods Acta Chimica Slovenica 55 2008 594 601
38. C.G.P.H. Schroen, M.A.C. Stuart, K.V. Maarschalk, A. Vanderpadt, and K. Vantriet Influence of preadsorbed block-copolymers on protein adsorption - surface-properties, layer thickness, and surface coverage Langmuir 11 1995 3068 3074
39. G.P. Vanderbeek, M.A.C. Stuart, G.J. Fleer, and J.E. Hofman Segmental adsorption energies for polymers on silica and alumina Macromolecules 24 1991 6600 6611
40. J. Buijs, P.A.W. vandenBerg, J.W.T. Lichtenbelt, W. Norde, and J. Lyklema Adsorption dynamics of IgG and its F(ab')(2) and Fc fragments studied by reflectometry Journal of Colloid and Interface Science 178 1996 594 605
41. W.B. Gratzer, and G.H. Beaven Relation between conformation and association state - a study of association equilibrium of glucagon Journal of Biological Chemistry 244 1969 6675 6679
42. K. Sasaki, S. Dockerill, D.A. Adamiak, I.J. Tickle, and T. Blundell X-ray analysis of glucagon and its relationship to receptor-binding Nature 257 1975 751 757
43. M.E. Wagman, C.M. Dobson, and M. Karplus Proton Nmr-studies of the association and folding of glucagon in solution Febs Letters 119 1980 265 270
44. E.A. Burstein, N.S. Vedenkina, and M.N. Ivkova Fluorescence and location of tryptophan residues in protein molecules Photochemistry and Photobiology 18 1973 263 279