Inner ear biocompatibility of lipid nanocapsules after round window membrane application

International Journal of Pharmaceutics

Volumn 404, Issue 1-2, 2011, Pages 211-219

  Zhang, Ya ^a   Zhang, Weikai ^a   Löbler, Marian ^b   Schmitz, Klaus Peter ^b   Saulnier, Patrick ^c   Perrier, Thomas ^c   Pyykkö, Ilmari ^a   Zou, Jing ^a  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b UNIVERSITY OF ROSTOCK   (Germany)

^c UNIVERSITÉ D'ANGERS   (France)

Author keywords

Cochlea; Molecular pathology; Nanoparticles; Rat; Toxicity

Indexed keywords

NANOCAPSULE; PROTEIN S 100; SYNAPTOPHYSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COCHLEA FENESTRA; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; FIBROBLAST; HEARING LOSS; INNER EAR DISEASE; MOUSE; NERVE CELL; NEUROFILAMENT; NONHUMAN; PRIORITY JOURNAL; RAT; SPIRAL LAMINA;

ACOUSTIC STIMULATION; ANIMALS; ANIMALS, NEWBORN; AUDITORY THRESHOLD; BIOCOMPATIBLE MATERIALS; CELL SURVIVAL; CELLS, CULTURED; CHEMISTRY, PHARMACEUTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; DRUG COMPOUNDING; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; FIBROBLASTS; INHIBITORY CONCENTRATION 50; LIPIDS; MALE; MICE; NANOCAPSULES; NANOTECHNOLOGY; PLANT LECTINS; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY; ROUND WINDOW, EAR; SOYBEAN PROTEINS; STEARATES; STEARIC ACIDS; TECHNOLOGY, PHARMACEUTICAL; TRIGLYCERIDES;

EID: 78650679714     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.11.006     Document Type: Article

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