The hsp27kD heat shock protein and p38-MAPK signaling are required for regular epidermal differentiation

Journal of Dermatological Science

Volumn 61, Issue 1, 2011, Pages 32-37

  Jonak, Constanze ^a   Mildner, Michael ^a   Klosner, Gabriele ^a   Paulitschke, Verena ^a   Kunstfeld, Rainer ^a   Pehamberger, Hubert ^a   Tschachler, Erwin ^a   Trautinger, Franz ^a,b  

^a Universitatsklinik fur Dermatologie   (Austria)

^b Karl Landsteiner Institute for Implementation of Innovative Techniques in Cardiac Surgery   (Austria)

Author keywords

Cornified cell envelope; Hsp27; Inhibition of hsp27 phosphorylation; Keratinocyte differentiation; P38 MAPK pathway

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CALCIUM ION; CYTOKERATIN 10; HEAT SHOCK PROTEIN 27; LORICRIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROFILAGGRIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; SMALL INTERFERING RNA;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; KERATINOCYTE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SKIN CULTURE;

CELL DIFFERENTIATION; CELLS, CULTURED; DOWN-REGULATION; GENE EXPRESSION; HSP27 HEAT-SHOCK PROTEINS; HUMANS; INTERMEDIATE FILAMENT PROTEINS; KERATIN-10; KERATINOCYTES; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RNA, SMALL INTERFERING; SKIN; SKIN PHYSIOLOGICAL PHENOMENA; TRANSGLUTAMINASES;

EID: 78650678308     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2010.10.009     Document Type: Article

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