Brain iron deposition and sequence characteristics in parkinsonism: Comparison of SWI, T2* maps, T2-weighted-, and FLAIR-SPACE

Investigative Radiology

Volumn 45, Issue 12, 2010, Pages 795-802

  Rossi, Maija ^a   Ruottinen, Hanna ^a   Elovaara, Irina ^a,b   Ryymin, Pertti ^a   Soimakallio, Seppo ^a,b   Eskola, Hannu ^a,c   Dastidar, Prasun ^a,b  

^a TAMPERE UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF TAMPERE MEDICAL SCHOOL   (Finland)

^c TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

Contrast; Iron; MRI; Parkinsonism

Indexed keywords

IRON;

ADULT; AGED; ARTICLE; BRAIN; BRAIN LEVEL; CLINICAL PROTOCOL; COMPARATIVE STUDY; DEGENERATIVE DISEASE; FEMALE; FLUID ATTENUATION INVERSION RECOVERY SAMPLING PERFECTION WITH APPLICATION OPTIMIZED CONTRAST USING DIFFERENT FLIP ANGLE EVOLUTION; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PARKINSONISM; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SAMPLING PERFECTION WITH APPLICATION OPTIMIZED CONTRAST USING DIFFERENT FLIP ANGLE EVOLUTION; SUSCEPTIBILITY WEIGHTED IMAGING;

EID: 78650677642     PISSN: 00209996     EISSN: 15360210     Source Type: Journal    
DOI: 10.1097/RLI.0b013e3181ec9c96     Document Type: Article

References (45)

1. Lees AJ, Hardy J, Revesz T. Parkinson's disease [review]. Lancet. 2009;373: 2055-2066.
2. 2 in the brain of healthy subjects, patients with Parkinson disease, and patients with multiple system atrophy: relation to iron content. Radiology. 1999;211:489-495.
3. Kosta P, Argyropoulou MI, Markoula S, Konitsiotis S. MRI evaluation of the basal ganglia size and iron content in patients with Parkinson's disease. J Neurol. 2006;253:26-32.
4. Brar S, Henderson D, Schenck J, et al. Iron accumulation in the substantia nigra of patients with Alzheimer disease and parkinsonism. Arch Neurol. 2009;66:371-374.
5. Graham JM, Paley MN, Grünewald RA, et al. Brain iron deposition in Parkinson's disease imaged using the PRIME magnetic resonance sequence. Brain. 2000;12:2423-2431.
6. Martin WR, Wieler M, Gee M. Midbrain iron content in early Parkinson disease: a potential biomarker of disease status. Neurology. 2008;70:1411-1417.
7. Dexter DT, Wells FR, Lees AJ, et al. Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease. J Neurochem. 1989;52:1830-1836.
8. Dexter DT, Carayon A, Javoy-Agid F, et al. Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia. Brain. 1991;114:1953-1975.
9. Griffiths PD, Dobson BR, Jones GR, et al. Iron in the basal ganglia in Parkinson's disease. An in vitro study using extended X-ray absorption fine structure and cryo-electron microscopy. Brain. 1999;122:667-673.
10. Bartzokis G, Cummings JL, Markham CH, et al. MRI evaluation of brain iron in earlier- and later-onset Parkinson's disease and normal subjects. Magn Reson Imaging. 1999;17:213-222.
11. Pfefferbaum A, Adalsteinsson E, Rohlfing T, et al. MRI estimates of brain iron concentration in normal aging: comparison of field-dependent (FDRI) and phase (SWI) methods. Neuroimage. 2009;47:493-500.
12. Haacke EM, Makki M, Ge Y, et al. Characterizing iron deposition in multiple sclerosis lesions using susceptibility weighted imaging. J Magn Reson Imaging. 2009;29:537-544.
13. Kirsch W, McAuley G, Holshouser B, et al. Serial susceptibility weighted MRI measures brain iron and microbleeds in dementia. J Alzheimers Dis. 2009;17:599-609.
14. Bastos Leite AJ, Scheltens P, Barkhof F. Pathological aging of the brain: an overview. Top Magn Reson Imaging. 2004;15:369-389.
15. 2-weighted CSF nulled IR sequences. J Comput Assist Tomogr. 1992;16:506-513.
16. De Coene B, Hajnal JV, Gatehouse P, et al. MR of the brain using fluidattenuated inversion recovery (FLAIR) pulse sequences. Am J Neuroradiol. 1992;13:1555-1564.
17. 2-weighted and FLAIR images: intraindividual comparison of 1. 5T and 3T MRI. Eur Radiol. 2008;18:2949-2955.
18. Mugler JP III, Bao S, Mulkern RV, et al. Optimized single-slab threedimensional spin-echo MR imaging of the brain. Radiology. 2000;216:891-899.
19. 2-weighted imaging of the brain using very long spin-echo trains. In: Proceedings of the International Society for Magnetic Resonance in Medicine 8th Meeting. Denver, CO: International Society for Magnetic Resonance in Medicine; 2000:687.
20. 2-weighted 3D spin-echo train imaging of the brain at 3 tesla: reduced power deposition using low flip-angle refocusing RF pulses. In: Proceedings of the International Society for Magnetic Resonance in Medicine 9th Meeting. Glasgow, Lanarkshire, United Kingdom: International Society for Magnetic Resonance in Medicine; 2001: 438.
21. Mugler JP III, Meyer H, Kiefer B. Practical implementation of optimized tissue-specific prescribed signal evolutions for improved turbo-spin-echo imaging. In: Proceedings of the International Society for Magnetic Resonance in Medicine 11th Meeting. Toronto, Ontario, Canada: International Society for Magnetic Resonance in Medicine; 2003:203.
22. 2-weighted turbo-spinecho sequence with high sampling efficiency (SPACE) for high spatial resolution imaging: initial clinical experiences. Invest Radiol. 2005;40:754-760.
23. Hughes T, Welsch GH, Trattnig S, et al. T2-star relaxation as a means to diffrentiatie cartilage repair tissue after microfracturing therapy. Proc ISMRM. 2007.
24. Welsch GH, Trattnig S, Hughes T, et al. T2 and T2* mapping in patients after matrix-associated autologous chondrocyte transplantation: initial results on clinical use with 3. 0-Tesla MRI. Eur Radiol. 2010;20:1515-1523.
25. 2* mapping of articular cartilage. Invest Radiol. 2008;43:619-626.
26. Martin AJ, Larson PS, Ostrem JL, et al. Placement of deep brain stimulator electrodes using real-time high-field interventional magnetic resonance imaging. Magn Reson Med. 2005;54:1107-1114.
27. Haacke EM, Xu Y, Cheng YC, et al. Susceptibility weighted imaging (SWI). Magn Reson Med. 2004;52:612-618.
28. Haacke EM, Mittal S, Wu Z, et al. Susceptibility-weighted imaging: technical aspects and clinical applications, part 1. Am J Neuroradiol. 2009;30:19-30.
29. Mittal S, Wu Z, Neelavalli J, et al. Susceptibility-weighted imaging: technical aspects and clinical applications, part 2. Am J Neuroradiol. 2009;30:232-252.
30. Mori N, Miki Y, Kasahara S, et al. Susceptibility-weighted imaging at 3 Tesla delineates the optic radiation. Invest Radiol. 2009;44:140-145.
31. Hallgren B, Sourander P. The effect of age on the non-haemin iron on in the human brain. J Neurochem. 1958;3:41-51.
32. Gelman N, Gorell JM, Barker PB, et al. MR imaging of human brain at 3.0 T: preliminary report on transverse relaxation rates and relation to estimated iron content. Radiology. 1999;210:759-767.
33. Ogg RJ, Langston JW, Haacke EM, et al. The correlation between phase shifts in gradient-echo MR images and regional brain iron concentration. Magn Reson Imaging. 1999;17:1141-1148.
34. Haque TL, Miki Y, Kanagaki M, et al. MR contrast of ferritin and hemosiderin in the brain: comparison among gradient-echo, conventional spin-echo and fast spin-echo sequences. Eur J Radiol. 2003;48:230-236.
35. Ashikaga R, Araki Y, Ono Y, et al. Appearance of normal brain maturation on fluid-attenuated inversion-recovery (FLAIR) MR images. Am J Neuroradiol. 1999;20:427-431.
36. Saatci I, Baskan O, Cekirge HS, et al. Comparison of MR sequences in early cerebral infarction at 0.5 T. Acta Radiol. 2000;41:553-558.
37. Gillis P, Koenig SH. Transverse relaxation of solvent protons induced by magnetized spheres: application to ferritin, erythrocytes, and magnetite. Magn Reson Med. 1987;5:323-345.
38. 2′ and hepatic iron content in thalassemic mice at 1.5 T and 3T. NMR Biomed. 2008;21:574-580.
39. 2* mapping accurately estimates hepatic iron concentration in transfusion-dependent thalassemia and sickle cell disease patients. Blood. 2005;106:1460-1465.
40. 2* measurements in myocardial siderosis in thalassemia. Magn Reson Med. 2009;61:501-506.
41. 2*-weighted, and susceptibility-weighted imaging methods in transgenic mouse models of Alzheimer's disease. Magn Reson Med. 2009;61:1158-1164.
42. Oros-Peusquens AM, Laurila M, Shah NJ. Magnetic field dependence of the distribution of NMR relaxation times in the living human brain. MAGMA. 2008;21:131-147.
43. 2 distributions and water contents in normal human brain. Magn Reson Med. 1997;37:34-43.
44. 2O patterns with quantitative MRI. Neuroimage. 2006;29:910-922.
45. Geis JR, Hendrick RE, Lee S, et al. White matter lesions: role of spin density in MR imaging. Radiology. 1989;170:863-868.