Aripiprazole protects cortical neurons from glutamate toxicity

European Journal of Pharmacology

Volumn 651, Issue 1-3, 2011, Pages 73-76

  Koprivica, Vuk ^a   Regardie, Karen ^a   Wolff, Christina ^a   Fernalld, Raymond ^a   Murphy, Janelle Johnson ^a   Kambayashi, Junichi ^a   Kikuchi, Tetsuro ^a,b   Jordan, Shaun ^a  

^a OTSUKA PHARMACEUTICAL DEVELOPMENT AND COMMERCIALIZATION INC   (United States)

^b OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Akt; Aripiprazole; Dopamine; Glutamate; GSK 3 ; Neuron; Neuroprotection; PARP; Serotonin

Indexed keywords

ARIPIPRAZOLE; DOPAMINE 2 RECEPTOR; GLUTAMIC ACID; GLYCOGEN SYNTHASE KINASE 3BETA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OLANZAPINE; PROTEIN KINASE B; RISPERIDONE; SEROTONIN 1A RECEPTOR;

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; BENZODIAZEPINES; CELL NUCLEUS; CEREBRAL CORTEX; CYTOPROTECTION; GLUTAMIC ACID; GLYCOGEN SYNTHASE KINASE 3; MOLECULAR IMAGING; NEURONS; NEUROPROTECTIVE AGENTS; PIPERAZINES; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-AKT; QUINOLONES; RATS; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTORS, DOPAMINE D2; RISPERIDONE; SEROTONIN 5-HT1 RECEPTOR ANTAGONISTS; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES;

EID: 78650677101     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.10.064     Document Type: Article

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