Effect of erythropoietin on the proliferation and apoptosis of neonatal porcine islet cells

Journal of Central South University (Medical Sciences)

Volumn 35, Issue 11, 2010, Pages 1115-1122

  He, Honghui ^a   Wu, Tianhui ^b   Xiong, Jing ^a   Chen, Ke ^a   Mo, Zhaohui ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b HUNAN CHILDREN'S HOSPITAL   (China)

Author keywords

Apoptosis; Erythropoietin; Islet cell; Neonatal porcine; Proliferation

Indexed keywords

CASPASE 3; ERYTHROPOIETIN; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECT; GENETICS; METABOLISM; NEWBORN; PANCREAS ISLET; SWINE;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL PROLIFERATION; CELLS, CULTURED; ERYTHROPOIETIN; ISLETS OF LANGERHANS; PROTO-ONCOGENE PROTEINS C-BCL-2; SWINE;

EID: 78650676138     PISSN: 16727347     EISSN: None     Source Type: Journal    
DOI: 10.3969/j.issn.1672-7347.2010.11.001     Document Type: Article

References (13)

1. Thomas F T, Contreras J L, Bilbao G, et al. Anoikis, extracellular matrix, and apoptosis factors in isolated cell transplantation [ J ]. Surgery, 1 999, 1 26 ( 2 ): 299-304.
2. Lau J, Henriksnäs J, Svensson J, et al. Oxygenation of islets and its role in transplantation [J]. Curr Opin Organ Transplant, 2009, 14(6): 688-693.
3. Fenjves E S, Ochoa M S, Cabrera O, et al. Human, nonhuman primate and rat pancreatic islets express erythropoietin receptors [J]. Transplantation, 2003, 75(8): 1356-1360. (Pubitemid 36513048)
4. Fenjves E S, Ochoa M S, Gay - Rabinstein C, et al. Adenoviral gene transfer of erythropoietin confers to isolated pancreatic islets[J]. Transplantation,2004,77(1): 13-18.
5. Rayat G R, Rajotte R V, Korbutt G S. Potential application of neonatal porcine islets as treatment for type 1 diabetes [J]. Ann NY Acad Sci, 1999, 18 (875): 175-181.
6. Nagai A, Nakagawa E, Choi H B, et al. Erythropoietin and erythropoietin receptors in human CNS neurons, astrocytes microglia, and oligodendrocytes grown in culture [J]. J Neuropathol Exp Neurol, 2001, 60(4): 386-392.
7. Buemi M, Lacquaniti A, Maricchiolo G, et al. Regenerative medicine : does erythropoietin have a role ? [J]. Curr Pharm Des, 2009, 15(17): 2026-2036.
8. Vandervelde S, van Luyn M J, Tio R A, et al. Signaling factors in stem cell - mediated repair of infarcted myocardium [J]. J Mol Cell Cardiol, 2005, 39(2): 363-376.
9. Byts N, Sirén A L. Erythropoietin: a multimodal neuroprotective agent [J]. Exp Transl Stroke Med, 2009, 21 (1): 4.
10. Zhang W, Sun B, Wang X, et al. Erythropoietin enhances survival of facial motor neurons by inhibiting expression of in ducible nitric oxide synthase after axotomy [J]. J Clin Neurosci, 2010, 17(3): 368-371.
11. Peshavaria M, Pang K. Manipulation of pancreatic stem cells for cell replacement therapy [J]. Diabetes Technol Ther, 2000, 2(3): 453-460.
12. Kaneto H, Miyatsuka T, Kawamori D, et al. PDX -1 and MafA play a crucial role in pancreatic beta-cell differentiation and maintenance of mature beta - cell function [J]. Endocr J, 2008, 55(2): 235-252. (Pubitemid 351670948)
13. Brissova M, Shostak A, Shiota M, et al. Pancreatic islet production of vascular endothelial growth factor-α is essential for islet vascularization, revascularization, and function [J]. Diabetes, 2006, 55(11): 2974-2985.