Involvement of multiple PKC isoforms in phorbol 12,13-dibutyrate-induced contraction during high K+ depolarization in bronchial smooth muscle of mice

Journal of Smooth Muscle Research

Volumn 46, Issue 5, 2010, Pages 225-233

  Sakai, Hiroyasu ^a   Kurihara, Yusuke ^a   Hashimoto, Yuki ^a   Chiba, Yoshihiko ^a   Misawa, Miwa ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Bronchial smooth muscle; Contraction; Phorbol 12,13 dibutyrate; Protein kinase C

Indexed keywords

CARCINOGEN; ISOENZYME; MESSENGER RNA; PHORBOL DIBUTYRATE; POTASSIUM; PROTEIN KINASE C;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BRONCHUS; DRUG EFFECT; ENZYMOLOGY; GENETICS; MALE; METABOLISM; MOUSE; MUSCLE CONTRACTION; MUSCLE TONE; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE;

ANIMALS; BRONCHI; CARCINOGENS; ISOENZYMES; MALE; MICE; MICE, INBRED BALB C; MUSCLE CONTRACTION; MUSCLE TONUS; MUSCLE, SMOOTH; PHORBOL 12,13-DIBUTYRATE; POTASSIUM; PROTEIN KINASE C; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 78650650228     PISSN: 09168737     EISSN: None     Source Type: Journal    
DOI: 10.1540/jsmr.46.225     Document Type: Article

References (23)

1. Chiba, Y., Nakazawa, S., Todoroki, M., Shinozaki, K., Sakai, H. and Misawa, M. (2009). Interleukin-13 augments bronchial smooth muscle contractility with an up-regulation of RhoA protein. Am. J. Respir. Cell Mol. Biol. 40: 159-167.
2. Chiba, Y., Shinozaki, K., Ueno, A., Sakai, H. and Misawa, M. (2008). Increased expression of G alpha q protein in bronchial smooth muscle of mice with allergic bronchial asthma. J. Smooth Muscle Res. 44: 95-100.
3. Eto, M., Ohmori, T., Suzuki, M., Furuya, K. and Morita, F. (1995). A novel protein phosphatase-1 inhibitory protein potentiated by protein kinase C. Isolation from porcine aorta media and characterization. J. Biochem. 118: 1104-1107.
4. Eto, M., Senba, S., Morita, F. and Yazawa, M. (1997). Molecular cloning of a novel phosphorylation-dependent inhibitory protein of protein phosphatase-1 (CPI17) in smooth muscle: its specific localization in smooth muscle. FEBS Lett. 410: 356-360.
5. Gschwendt, M., Müller, H.J., Kielbassa, K., Zang, R., Kittstein, W., Rincke, G. and Marks, F. (1994). Rottlerin, a novel protein kinase inhibitor. Biochem. Biophys. Res. Commun. 199: 93-98.
6. Hakonarson, H. and Grunstein, M.M. (1998). Regulation of second messengers associated with airway smooth muscle contraction and relaxation. Am. J. Respir. Crit. Care Med. 158: S115-S122.
7. Hug, H. and Sarre, T.F. (1993). Protein kinase C isoenzymes: divergence in signal transduction? Biochem. J. 291: 329-343.
8. Inoue, M., Kishimoto, A., Takai, Y. and Nishizuka, Y. (1977). Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain. J. Biol. Chem. 252: 7610-7616.
9. 2+-independent vasocontraction. Am. J. Physiol. 265: C1319-C1324.
10. 2+ and contraction in norepinephrine-stimulated vascular smooth muscle. Jpn. J. Pharmacol. 55: 35-42.
11. Li, L., Eto, M., Lee, M.R., Morita, F., Yazawa, M. and Kitazawa, T. (1998). Possible involvement of the novel CPI-17 protein in protein kinase C signal transduction of rabbit arterial smooth muscle. J. Physiol. (Lond.) 508: 871-881.
12. Martiny-Baron, G., Kazanietz, M.G., Mischak, H., Blumberg, P.M., Kochs, G., Hug, H., Marmé, D. and Schächtele, C. (1993). Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976. J. Biol. Chem. 268: 9194-9197.
13. 2+-sensitizing effect of protein kinase C on vascular smooth muscle: inhibition of myosin light chain phosphatase. J. Gen. Physiol. 104: 265-286.
14. Rossetti, M., Savineau, J.P., Crevel, H. and Marthan, R. (1995). Role of protein kinase C in nonsensitized and passively sensitized human isolated bronchial smooth muscle. Am. J. Physiol. 268: L966-L971.
15. Sakai, H., Chiba, Y. and Misawa, M. (2007). Role of Rho kinase in endothelin-1-induced phosphorylation of CPI-17 in rat bronchial smooth muscle. Pulm. Pharmacol. Ther. 20: 734-739.
16. Sakai, H., Hirano, T., Takeyama, H., Chiba, Y. and Misawa, M. (2005). Acetylcholine-induced phosphorylation of CPI-17 in rat bronchial smooth muscle: the roles of Rho-kinase and protein kinase C. Can. J. Physiol. Pharmacol. 83: 375-381.
17. Sakai, H., Yamamoto, M., Chiba, Y. and Misawa, M. (2008). Probable involvement of epsilon-isoform of protein kinase C in rat bronchial smooth muscle contraction induced by acetylcholine. J. Smooth Muscle Res. 44: 9-16.
18. Sakai, H., Yamamoto, M., Chiba, Y. and Misawa, M. (2009). Some different effect of PKC inhibitors on the acetylcholine, and endothelin-1-induced contractions of rat bronchial smooth muscle. Eur. J. Pharmacol. 618: 58-62.
19. Salamanca, D.A. and Khalil, R.A. (2005). Protein kinase C isoforms as specific targets for modulation of vascular smooth muscle function in hypertension. Biochem. Pharmacol. 70: 1537-1547.
20. Stabel, S. and Parker, P.J. (1991). Protein kinase C. Pharmacol. Ther. 51: 71-95.
21. Takai, Y., Kishimoto, A., Inoue, M. and Nishizuka, Y. (1977). Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. I. Purification and characterization of an active enzyme from bovine cerebellum. J. Biol. Chem. 252: 7603-7609.
22. Webb, B.L., Lindsay, M.A., Seybold, J., Brand, N.J., Yacoub, M.H., Haddad, E.B., Barnes, P.J., Adcock, I.M. and Giembycz, M.A. (1997). Identification of the protein kinase C isoenzymes in human lung and airways smooth muscle at the protein and mRNA level. Biochem. Pharmacol. 54: 199-205.
23. 2+ sensitivity of protein kinase C-induced contraction in rabbit smooth muscle. J. Physiol. (Lond.) 535: 553-564.