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Volumn 26, Issue 1, 2011, Pages 239-245

The HUMN and HUMNxL international collaboration projects on human micronucleus assays in lymphocytes and buccal cells-past, present and future

Author keywords

[No Author keywords available]

Indexed keywords

AGE; AUTOMATION; CANCER RISK; CHEEK; CLINICAL PROTOCOL; CYTOKINESIS; DNA DAMAGE; EPITHELIUM CELL; ERYTHROCYTE; FLOW CYTOMETRY; GENDER; HUMAN; IMAGE ANALYSIS; LASER SCANNING CYTOMETRY; LYMPHOCYTE; MICRONUCLEUS TEST; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; RELIABILITY; REVIEW; SCORING SYSTEM; SMOKING; STANDARDIZATION; TISSUE CULTURE; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; FACTUAL DATABASE; INTERNATIONAL COOPERATION; MOUTH MUCOSA; NEOPLASM; ULTRASTRUCTURE;

EID: 78650639748     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/geq051     Document Type: Review
Times cited : (178)

References (30)
  • 1
    • 0021987630 scopus 로고
    • Measurement of micronuclei in lymphocytes
    • Fenech, M. and Morley, A. A. (1985) Measurement of micronuclei in lymphocytes. Mutat. Res., 147, 29-36.
    • (1985) Mutat. Res. , vol.147 , pp. 29-36
    • Fenech, M.1    Morley, A.A.2
  • 2
    • 0022589981 scopus 로고
    • Cytokinesis-block micronucleus method in human lymphocytes: Effect of in vivo ageing and low dose X-irradiation
    • Fenech, M. and Morley, A. A. (1986) Cytokinesis-block micronucleus method in human lymphocytes: effect of in vivo ageing and low dose X-irradiation. Mutat. Res., 161, 193-198.
    • (1986) Mutat. Res. , vol.161 , pp. 193-198
    • Fenech, M.1    Morley, A.A.2
  • 3
    • 0032785259 scopus 로고    scopus 로고
    • The HUman MicroNucleus Project-An international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans
    • Fenech, M., Holland, N., Chang, W. P., Zeiger, E. and Bonassi, S. (1999) The HUman MicroNucleus Project-An international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans. Mutat. Res., 428, 271-283.
    • (1999) Mutat. Res. , vol.428 , pp. 271-283
    • Fenech, M.1    Holland, N.2    Chang, W.P.3    Zeiger, E.4    Bonassi, S.5
  • 4
    • 0035144198 scopus 로고    scopus 로고
    • HUman MicroNucleus project: International database comparison for results with the cytokinesis-block micronucleus assay in human lymphocytes: I. Effect of laboratory protocol, scoring criteria, and host factors on the frequency of micronuclei
    • Bonassi, S., Fenech, M., Lando, C. et al. (2001) HUman MicroNucleus project: international database comparison for results with the cytokinesis-block micronucleus assay in human lymphocytes: I. Effect of laboratory protocol, scoring criteria, and host factors on the frequency of micronuclei. Environ. Mol. Mutagen., 37, 31-45.
    • (2001) Environ. Mol. Mutagen. , vol.37 , pp. 31-45
    • Bonassi, S.1    Fenech, M.2    Lando, C.3
  • 5
    • 0037427878 scopus 로고    scopus 로고
    • HUman MicronNucleus project. HUMN project: Detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures
    • Fenech, M., Chang, W. P., Kirsch-Volders, M., Holland, N., Bonassi, S. and Zeiger, E. (2003) HUman MicronNucleus project. HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures. Mutat. Res., 534, 65-75.
    • (2003) Mutat. Res. , vol.534 , pp. 65-75
    • Fenech, M.1    Chang, W.P.2    Kirsch-Volders, M.3    Holland, N.4    Bonassi, S.5    Zeiger, E.6
  • 7
    • 0037339166 scopus 로고    scopus 로고
    • HUMN collaborative group. Effect of smoking habit on the frequency of micronuclei in human lymphocytes: Results from the Human MicroNucleus project
    • Bonassi, S., Neri, M., Lando, C. et al. (2003) HUMN collaborative group. Effect of smoking habit on the frequency of micronuclei in human lymphocytes: results from the Human MicroNucleus project. Mutat. Res., 543, 155-166.
    • (2003) Mutat. Res. , vol.543 , pp. 155-166
    • Bonassi, S.1    Neri, M.2    Lando, C.3
  • 8
    • 34047154552 scopus 로고    scopus 로고
    • An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans
    • Bonassi, S., Znaor, A., Ceppi, M. et al. (2007) An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans. Carcinogenesis, 28, 625-631.
    • (2007) Carcinogenesis , vol.28 , pp. 625-631
    • Bonassi, S.1    Znaor, A.2    Ceppi, M.3
  • 9
    • 34250187067 scopus 로고    scopus 로고
    • Cytokinesis-block micronucleus cytome assay
    • Fenech, M. (2007) Cytokinesis-block micronucleus cytome assay. Nat. Protoc., 2, 1084-1104.
    • (2007) Nat. Protoc. , vol.2 , pp. 1084-1104
    • Fenech, M.1
  • 10
    • 84880583922 scopus 로고    scopus 로고
    • In vitro mammalian cell micronucleus test (MNvit)
    • OECD OECD, Paris, France accessed September 1, 2010
    • OECD. (2010) In Vitro Mammalian Cell Micronucleus Test (MNvit). OECD Guideline for Testing of Chemicals No. 487. OECD, Paris, France. http://titania.sourceoecd.org/vl=21252130/cl=33/nw=1/rpsv/ij/oecdjournals /1607310x/v1n4/s62/p1 (accessed September 1, 2010).
    • (2010) OECD Guideline for Testing of Chemicals No. 487
  • 11
    • 52649132933 scopus 로고    scopus 로고
    • Cytokinesis-blocked micronucleus cytome assay biomarkers identify lung cancer cases amongst smokers
    • El-Zein, R. A., Fenech, M., Lopez, M. S., Spitz, M. R. and Etzel, C. J. (2008) Cytokinesis-blocked micronucleus cytome assay biomarkers identify lung cancer cases amongst smokers. Cancer Epidemiol. Bio-markers Prev., 17, 1111-1119.
    • (2008) Cancer Epidemiol. Bio-markers Prev. , vol.17 , pp. 1111-1119
    • El-Zein, R.A.1    Fenech, M.2    Lopez, M.S.3    Spitz, M.R.4    Etzel, C.J.5
  • 12
    • 33745685857 scopus 로고    scopus 로고
    • Cytokinesis-blocked micronucleus assay as a novel biomarker for lung cancer risk
    • El-Zein, R. A., Schabath, M. B., Etzel, C. J., Lopez, M. S., Franklin, J. D. and Spitz, M. R. (2006) Cytokinesis-blocked micronucleus assay as a novel biomarker for lung cancer risk. Cancer Res., 66, 6449-6456.
    • (2006) Cancer Res. , vol.66 , pp. 6449-6456
    • El-Zein, R.A.1    Schabath, M.B.2    Etzel, C.J.3    Lopez, M.S.4    Franklin, J.D.5    Spitz, M.R.6
  • 13
    • 77956253491 scopus 로고    scopus 로고
    • Increased lymphocyte micronucleus frequency in early pregnancy is associated prospectively with pre-eclampsia and/or intrauterine growth restriction
    • Furness, D. L., Dekker, G. A., Hague, W. M., Khong, T. Y. and Fenech, M. F. (2010) Increased lymphocyte micronucleus frequency in early pregnancy is associated prospectively with pre-eclampsia and/or intrauterine growth restriction. Mutagenesis, 25, 489-498.
    • (2010) Mutagenesis , vol.25 , pp. 489-498
    • Furness, D.L.1    Dekker, G.A.2    Hague, W.M.3    Khong, T.Y.4    Fenech, M.F.5
  • 14
    • 34447269629 scopus 로고    scopus 로고
    • Micronuclei, genetic polymorphisms and cardiovascular disease mortality in a nested case-control study in Italy
    • Murgia, E., Maggini, V., Barale, R. and Rossi, A. M. (2007) Micronuclei, genetic polymorphisms and cardiovascular disease mortality in a nested case-control study in Italy. Mutat. Res., 621, 113-118.
    • (2007) Mutat. Res. , vol.621 , pp. 113-118
    • Murgia, E.1    Maggini, V.2    Barale, R.3    Rossi, A.M.4
  • 15
    • 55249087914 scopus 로고    scopus 로고
    • Relation of increased chromosomal damage to future adverse cardiac events in patients with known coronary artery disease
    • Federici, C., Botto, N., Manfredi, S., Rizza, A., Del Fiandra, M. and Andreassi, M. G. (2008) Relation of increased chromosomal damage to future adverse cardiac events in patients with known coronary artery disease. Am. J. Cardiol., 102, 1296-1300.
    • (2008) Am. J. Cardiol. , vol.102 , pp. 1296-1300
    • Federici, C.1    Botto, N.2    Manfredi, S.3    Rizza, A.4    Del Fiandra, M.5    Andreassi, M.G.6
  • 16
    • 33744757688 scopus 로고    scopus 로고
    • The effects of GSTM1 and GSTT1 polymorphisms on micronucleus frequencies in human lymphocytes in vivo
    • Kirsch-Volders, M., Mateuca, R. A., Roelants, M. et al. (2006) The effects of GSTM1 and GSTT1 polymorphisms on micronucleus frequencies in human lymphocytes in vivo. Cancer Epidemiol. Biomarkers Prev., 15, 1038-1042.
    • (2006) Cancer Epidemiol. Biomarkers Prev. , vol.15 , pp. 1038-1042
    • Kirsch-Volders, M.1    Mateuca, R.A.2    Roelants, M.3
  • 17
    • 38549115259 scopus 로고    scopus 로고
    • HOGG1(326), XRCC1(399) and XRCC3(241) polymorphisms influence micronucleus frequencies in human lymphocytes in vivo
    • Mateuca, R. A., Roelants, M., Iarmarcovai, G. et al. (2008) hOGG1(326), XRCC1(399) and XRCC3(241) polymorphisms influence micronucleus frequencies in human lymphocytes in vivo. Mutagenesis, 23, 35-41.
    • (2008) Mutagenesis , vol.23 , pp. 35-41
    • Mateuca, R.A.1    Roelants, M.2    Iarmarcovai, G.3
  • 18
    • 43149090300 scopus 로고    scopus 로고
    • Genetic polymorphisms and micronucleus formation: A review of the literature
    • Iarmarcovai, G., Bonassi, S., Botta, A., Baan, R. A. and Orsière, T. (2008) Genetic polymorphisms and micronucleus formation: a review of the literature. Mutat. Res., 658, 215-233.
    • (2008) Mutat. Res. , vol.658 , pp. 215-233
    • Iarmarcovai, G.1    Bonassi, S.2    Botta, A.3    Baan, R.A.4    Orsière, T.5
  • 20
    • 47849123302 scopus 로고    scopus 로고
    • The micronucleus assay in human buccal cells as a tool for biomonitoring DNA damage: The HUMN project perspective on current status and knowledge gaps
    • Holland, N., Bolognesi, C., Kirsch-Volders, M., Bonassi, S., Zeiger, E., Knasmueller, S. and Fenech, M. (2008) The micronucleus assay in human buccal cells as a tool for biomonitoring DNA damage: the HUMN project perspective on current status and knowledge gaps. Mutat. Res., 659, 93-108.
    • (2008) Mutat. Res. , vol.659 , pp. 93-108
    • Holland, N.1    Bolognesi, C.2    Kirsch-Volders, M.3    Bonassi, S.4    Zeiger, E.5    Knasmueller, S.6    Fenech, M.7
  • 21
    • 33846113496 scopus 로고    scopus 로고
    • Harmonisation of the micronucleus assay in human buccal cells-a Human Micronucleus (HUMN) project
    • www.humn.org initiative commencing in 2007
    • Fenech, M., Bolognesi, C., Kirsch-Volders, M., Bonassi, S., Zeiger, E., Knasmüller, S. and Holland, N. (2007) Harmonisation of the micronucleus assay in human buccal cells-a Human Micronucleus (HUMN) project (www.humn.org) initiative commencing in 2007. Mutagenesis, 22, 3-4.
    • (2007) Mutagenesis , vol.22 , pp. 3-4
    • Fenech, M.1    Bolognesi, C.2    Kirsch-Volders, M.3    Bonassi, S.4    Zeiger, E.5    Knasmüller, S.6    Holland, N.7
  • 22
    • 61649099068 scopus 로고    scopus 로고
    • Report on the buccal micronucleus assay workshop organized by the International Human Micronucleus (HUMN) project-Antalya, Turkey 2007
    • Fenech, M., Holland, N., Knasmueller, S., Burgaz, S. and Bonassi, S. (2009) Report on the buccal micronucleus assay workshop organized by the International Human Micronucleus (HUMN) project-Antalya, Turkey 2007. Mutagenesis, 24, 199-201.
    • (2009) Mutagenesis , vol.24 , pp. 199-201
    • Fenech, M.1    Holland, N.2    Knasmueller, S.3    Burgaz, S.4    Bonassi, S.5
  • 23
    • 67650921921 scopus 로고    scopus 로고
    • State of the art survey of the buccal micronucleus assay-a first stage in the HUMN(XL) project initiative
    • Bonassi, S., Biasotti, B., Kirsch-Volders, M. et al. (2009) State of the art survey of the buccal micronucleus assay-a first stage in the HUMN(XL) project initiative. Mutagenesis, 24, 295-302.
    • (2009) Mutagenesis , vol.24 , pp. 295-302
    • Bonassi, S.1    Biasotti, B.2    Kirsch-Volders, M.3
  • 25
    • 77952552218 scopus 로고    scopus 로고
    • Human population studies with the exfoliated buccal micronucleus assay: Statistical and epidemiological issues
    • Ceppi, M., Biasotti, B., Fenech, M. and Bonassi, S. (2010) Human population studies with the exfoliated buccal micronucleus assay: statistical and epidemiological issues. Mutat. Res., 705, 11-19.
    • (2010) Mutat. Res. , vol.705 , pp. 11-19
    • Ceppi, M.1    Biasotti, B.2    Fenech, M.3    Bonassi, S.4
  • 27
    • 77749334551 scopus 로고    scopus 로고
    • Increased micronucleus frequencies in surrogate and target cells from workers exposed to crystalline silica-containing dust
    • Demircigil, G. C., Coskun, E., Vidinli, N., Erbay, Y., Yilmaz, M., Cimrin, A., Schins, R. P., Borm, P. J. and Burgaz, S. (2010) Increased micronucleus frequencies in surrogate and target cells from workers exposed to crystalline silica-containing dust. Mutagenesis, 25, 163-169.
    • (2010) Mutagenesis , vol.25 , pp. 163-169
    • Demircigil, G.C.1    Coskun, E.2    Vidinli, N.3    Erbay, Y.4    Yilmaz, M.5    Cimrin, A.6    Schins, R.P.7    Borm, P.J.8    Burgaz, S.9
  • 28
    • 0035170551 scopus 로고    scopus 로고
    • Inclusion of micronuclei in non-divided mononuclear lymphocytes and necrosis/apoptosis may provide a more comprehensive cytokinesis block micronucleus assay for bio-monitoring purposes
    • Kirsch-Volders, M. and Fenech, M. (2001) Inclusion of micronuclei in non-divided mononuclear lymphocytes and necrosis/apoptosis may provide a more comprehensive cytokinesis block micronucleus assay for bio-monitoring purposes. Mutagenesis, 16, 51-58.
    • (2001) Mutagenesis , vol.16 , pp. 51-58
    • Kirsch-Volders, M.1    Fenech, M.2
  • 29
    • 78650638363 scopus 로고    scopus 로고
    • Effect of obesity diabetes and cardiovascular disease on micronucleus frequency
    • (in press)
    • Andreassi, M. G., Barale, R., Iozzo, P. and Picano, E. (2010) Effect of obesity, diabetes and cardiovascular disease on micronucleus frequency. Mutagenesis, (in press).
    • (2010) Mutagenesis
    • Andreassi, M.G.1    Barale, R.2    Iozzo, P.3    Picano, E.4
  • 30
    • 78650674257 scopus 로고    scopus 로고
    • Association of micronucleus frequency with neurodegenerative diseases
    • (in press)
    • Migliore, L., Coppedè, F., Fenech, M. and Thomas, P. (2010) Association of micronucleus frequency with neurodegenerative diseases. Mutagenesis, (in press).
    • (2010) Mutagenesis
    • Migliore, L.1    Coppedè, F.2    Fenech, M.3    Thomas, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.