Micronuclei, genetic polymorphisms and cardiovascular disease mortality in a nested case-control study in Italy

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 621, Issue 1-2, 2007, Pages 113-118

  Murgia, Elena ^a   Maggini, Valentina ^a   Barale, Roberto ^a   Rossi, Anna Maria ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Biomarkers; CVD death; Genetic polymorphisms; Micronuclei

Indexed keywords

GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE T1;

ADULT; AGED; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CASE CONTROL STUDY; CAUSE OF DEATH; CONTROLLED STUDY; CYTOGENETICS; FEMALE; FOLLOW UP; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; ITALY; MAJOR CLINICAL STUDY; MALE; MICRONUCLEUS; MORTALITY; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; CARDIOVASCULAR DISEASES; CASE-CONTROL STUDIES; FEMALE; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; ITALY; MALE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MIDDLE AGED; POLYMORPHISM, GENETIC;

EID: 34447269629     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2007.02.015     Document Type: Article

References (22)

1. WHO, World Health Organization, www.who.int/, Mortality Database.
2. Trosko J., and Chan C. An integrative hipothesis linking cancer, diabetes and atherosclerosis: the role of mutations and epigenetic changes. Med. Hypoth. 6 (1980) 455-468
3. De Flora S., Izzotti A., Randerath K., Randerath E., Bartsch H., Nair J., Balansky R., van Schooten F., Degan P., Fronza G., Walsh D., and Lewtas J. DNA adducts and chronic degenerative disease. Pathogenetic relevance and implications in preventive medicine. Mutat. Res. 366 (1996) 197-238
4. Ross R. Atherosclerosis is an inflammatory disease. Am. Heart J. 138 (1999) S419-S420
5. Andreassi M.G., and Botto N. DNA damage as a new emerging risk factor in atherosclerosis. Trends Cardiovasc. Med. 13 (2003) 270-275
6. Benditt E.P., and Benditt J.M. Evidence for a monoclonal origin of human atherosclerotic plaques. Proc. Natl. Acad. Sci. U.S.A. 70 (1973) 1753-1756
7. Van Schooten F.J., Hirvonen A., Maas L.M., De Mol B.A., Kleinjans J.C., Bell D.A., and Durrer J.D. Putative susceptibility markers of coronary artery disease: association between VDR genotype, smoking, and aromatic DNA adduct levels in human right atrial tissue. FASEB J. 12 (1998) 1409-1417
8. De Flora S., Izzotti A., Walsh D., Degan P., Petrilli G.L., and Lewtas J. Molecular epidemiology of atherosclerosis. FASEB J. 11 (1997) 1021-1031
9. Izzotti A., Camoirano A., Cartiglia C., Tampa E., and De Flora S. Formation of DNA adducts in the aorta of smoke-exposed rats, and modulation by chemopreventive agents. Mutat. Res. 494 (2001) 97-106
10. Botto N., Rizza A., Colombo M.G., Mazzone A.M., Manfredi S., Masetti S., Clerico A., Biagini A., and Andreassi M.G. Evidence for DNA damage in patients with coronary artery disease. Mutat. Res. 493 (2001) 23-30
11. Andreassi M.G., Botto N., Rizza A., Colombo M.G., Palmieri C., Berti S., Manfredi S., Masetti S., Clerico A., and Bigini A. Deoxyribonucleic acid damage in human lymphocytes after percutaneous transluminal coronary angioplasty. J. Am. Coll. Cardiol. 40 (2002) 862-868
12. Manfredi S., Masetti S., Botto N., Colombo M.G., Terrazzi M., Vassalle C., Biagini A., and Andreassi M.G. P53 codon 72 polymorphism in coronary artery disease: no evidence for association with increased risk or micronucleus frequency. Environ. Mol. Mutagen. 40 2 (2002) 110-115
13. Izzotti A., Cartiglia C., Lewtas J., and De Flora S. Increased DNA alterations in atherosclerotic lesions of individuals lacking the GSTM1 genotype. FASEB J. 15 (2001) 752-757
14. Wilson M.H., Grant P.J., Hardie L.J., and Wild C.P. Glutathione-S-transferase M1 null genotype is associated with a decreased risk of myocardial infarction. FASEB J. 14 (2000) 791-796
15. Salama S.A., Au W.W., Hunter G.C., Sheahan R.G., Badary O.A., Abdel-Naim A.B., and Hamada F.M. Polymorphic metabolizing genes and susceptibility to atherosclerosis among cigarette smokers. Environ. Mol. Mutagen. 40 3 (2002) 153-160
16. Olshan A.F., Li R., Pankow J.S., Bray M., Tyroler H.A., Chambless L.E., Boerwinkle E., Pittman G.S., and Bell D.A. Risk of atherosclerosis: interaction of smoking and glutathione S-transferase genes. Epidemiology 14 (2003) 321-327
17. Habdous M., Siest G., Herberth B., Vincent-Viry M., and Visvikis S. Glutathione S-transferases genetic polymorphisms and human disease: overview of epidemiological studies. Ann. Biol. Clin. (Paris) 62 1 (2004) 15-24
18. Masetti S., Botto N., Manfredi S., Colombo M.G., Rizza A., Vassalle C., Clerico A., Bigini A., and Andreassi M.G. Interactive effect of the glutathione S-transferase genes and cigarette smoking on occurrence and severity of coronary artery risk. J. Mol. Med. 81 8 (2003) 453-454
19. Fenech M., and Morley A. A measurement of micronuclei in lymphocytes. Mutat. Res. 147 1-2 (1985) 29-36
20. Cox D.R., and Oakes D. Analysis of Survival Data (1984), Chapman and Hale, London
21. Landi S., Iazzolino E., and Barale R. Are baseline frequencies of SCEs, CAs, and MN in human lymphocytes related to hematological values?. Mutat. Res. 469 (2000) 159-166
22. Kelada S.N., Kardia S.L., Walker A.H., Wein A.J., Malkowicz S.B., and Rebbeck T.R. The glutathione S-transferase-mu and -theta genotypes in the etiology of prostate cancer: genotype-environment interactions with smoking. Cancer Epidemiol. Biomarkers Prev. 9 (2000) 1329-1334