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Volumn 107, Issue 45, 2010, Pages 19396-19401

FcYγRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo

Author keywords

Autoimmune disease; Immunoglobulin G; Inflammation

Indexed keywords

CD11B ANTIGEN; CD16 ANTIGEN; FC RECEPTOR; FC RECEPTOR IV; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; UNCLASSIFIED DRUG; FCGR4 PROTEIN, MOUSE; IMMUNOGLOBULIN G;

EID: 78650608742     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1014515107     Document Type: Article
Times cited : (155)

References (31)
  • 1
    • 0036888558 scopus 로고    scopus 로고
    • Fc receptors are major mediators of antibody based inflammation in autoimmunity
    • Hogarth P.M.
    • Hogarth PM (2002) Fc receptors are major mediators of antibody based inflammation in autoimmunity. Curr Opin Immunol 14:798-802.
    • (2002) Curr Opin Immunol , vol.14 , pp. 798-802
  • 2
    • 77953760056 scopus 로고    scopus 로고
    • Antibody-mediated modulation of immune responses
    • Nimmerjahn F, Ravetch JV (2010) Antibody-mediated modulation of immune responses. Immunol Rev 236:265-275.
    • (2010) Immunol Rev , vol.236 , pp. 265-275
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 3
    • 0036676975 scopus 로고    scopus 로고
    • Roles of Fc receptors in autoimmunity
    • Takai T (2002) Roles of Fc receptors in autoimmunity. Nat Rev Immunol 2:580-592.
    • (2002) Nat Rev Immunol , vol.2 , pp. 580-592
    • Takai, T.1
  • 4
    • 37549036732 scopus 로고    scopus 로고
    • Fcgamma receptors as regulators of immune responses
    • Nimmerjahn F, Ravetch JV (2008) Fcgamma receptors as regulators of immune responses. Nat Rev Immunol 8:34-47.
    • (2008) Nat Rev Immunol , vol.8 , pp. 34-47
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 5
    • 17344368340 scopus 로고    scopus 로고
    • Divergent roles for fc receptors and complement in vivo
    • Ravetch JV, Clynes RA (1998) Divergent roles for Fc receptors and complement in vivo. Annu Rev Immunol 16:421-432.
    • (1998) Annu Rev Immunol , vol.16 , pp. 421-432
    • Ravetch, J.V.1    Clynes, R.A.2
  • 6
    • 34548496893 scopus 로고    scopus 로고
    • Fc receptor but not complement binding is important in antibody protection against HIV
    • Hessell AJ, et al. (2007) Fc receptor but not complement binding is important in antibody protection against HIV. Nature 449:101-104.
    • (2007) Nature , vol.449 , pp. 101-104
    • Hessell, A.J.1
  • 7
    • 0036464719 scopus 로고    scopus 로고
    • Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in igg fc receptor fcgammariiia gene
    • Cartron G, et al. (2002) Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene. Blood 99:754-758.
    • (2002) Blood , vol.99 , pp. 754-758
    • Cartron, G.1
  • 8
    • 14544301233 scopus 로고    scopus 로고
    • Clinical outcome of lymphoma patients after idiotype vaccination is correlated with humoral immune response and immunoglobulin G Fc receptor genotype
    • Weng WK, Czerwinski D, Timmerman J, Hsu FJ, Levy R (2004) Clinical outcome of lymphoma patients after idiotype vaccination is correlated with humoral immune response and immunoglobulin G Fc receptor genotype. J Clin Oncol 22:4717-4724.
    • (2004) J Clin Oncol , vol.22 , pp. 4717-4724
    • Weng, W.K.1    Czerwinski, D.2    Timmerman, J.3    Hsu, F.J.4    Levy, R.5
  • 9
    • 0642373290 scopus 로고    scopus 로고
    • Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma
    • Weng WK, Levy R (2003) Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma. J Clin Oncol 21:3940-3947.
    • (2003) J Clin Oncol , vol.21 , pp. 3940-3947
    • Weng, W.K.1    Levy, R.2
  • 10
    • 0034678446 scopus 로고    scopus 로고
    • Markedly different pathogenicity of four immunoglobulinG isotype-switch variants of an antierythrocyte autoantibody is based on their capacity to interact in vivo with the low-affinity Fcgamma receptor III
    • Fossati-Jimack L, et al. (2000)Markedly different pathogenicity of four immunoglobulinG isotype-switch variants of an antierythrocyte autoantibody is based on their capacity to interact in vivo with the low-affinity Fcgamma receptor III. J ExpMed 191:1293-1302.
    • (2000) J ExpMed , vol.191 , pp. 1293-1302
    • Fossati-Jimack, L.1
  • 11
    • 33645053518 scopus 로고    scopus 로고
    • Antibody isotypespecific engagement of Fcgamma receptors regulates B lymphocyte depletion during CD20 immunotherapy
    • Hamaguchi Y, Xiu Y, Komura K, Nimmerjahn F, Tedder TF (2006) Antibody isotypespecific engagement of Fcgamma receptors regulates B lymphocyte depletion during CD20 immunotherapy. J Exp Med 203:743-753.
    • (2006) J Exp Med , vol.203 , pp. 743-753
    • Hamaguchi, Y.1    Xiu, Y.2    Komura, K.3    Nimmerjahn, F.4    Tedder, T.F.5
  • 12
    • 16044366240 scopus 로고    scopus 로고
    • Impaired IgG-dependent anaphylaxis and arthus reaction in fc gamma RIII (CD16) deficient mice
    • Hazenbos WL, et al. (1996) Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice. Immunity 5:181-188.
    • (1996) Immunity , vol.5 , pp. 181-188
    • Hazenbos, W.L.1
  • 13
    • 0032217049 scopus 로고    scopus 로고
    • FcgammaRIII (CD16)-deficient mice show IgG isotype-dependent protection to experimental autoimmune hemolytic anemia
    • Meyer D, et al. (1998) FcgammaRIII (CD16)-deficient mice show IgG isotype-dependent protection to experimental autoimmune hemolytic anemia. Blood 92:3997-4002.
    • (1998) Blood , vol.92 , pp. 3997-4002
    • Meyer, D.1
  • 14
    • 28544449847 scopus 로고    scopus 로고
    • Divergent immunoglobulin g subclass activity through selective Fc receptor binding
    • Nimmerjahn F, Ravetch JV (2005) Divergent immunoglobulin g subclass activity through selective Fc receptor binding. Science 310:1510-1512.
    • (2005) Science , vol.310 , pp. 1510-1512
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 15
    • 22544487815 scopus 로고    scopus 로고
    • FcgammaRIV: A novel FcR with distinct IgG subclass specificity
    • Nimmerjahn F, Bruhns P, Horiuchi K, Ravetch JV (2005) FcgammaRIV: A novel FcR with distinct IgG subclass specificity. Immunity 23:41-51.
    • (2005) Immunity , vol.23 , pp. 41-51
    • Nimmerjahn, F.1    Bruhns, P.2    Horiuchi, K.3    Ravetch, J.V.4
  • 16
    • 0036009179 scopus 로고    scopus 로고
    • FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses
    • Barnes N, et al. (2002) FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses. Immunity 16:379-389.
    • (2002) Immunity , vol.16 , pp. 379-389
    • Barnes, N.1
  • 17
    • 18344370440 scopus 로고    scopus 로고
    • FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection
    • Ioan-Facsinay A, et al. (2002) FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. Immunity 16:391-402.
    • (2002) Immunity , vol.16 , pp. 391-402
    • Ioan-Facsinay, A.1
  • 18
    • 34250757026 scopus 로고    scopus 로고
    • IgEb immune complexes activate macrophages through FcgammaRIV binding
    • Hirano M, et al. (2007) IgEb immune complexes activate macrophages through FcgammaRIV binding. Nat Immunol 8:762-771.
    • (2007) Nat Immunol , vol.8 , pp. 762-771
    • Hirano, M.1
  • 19
    • 55949123945 scopus 로고    scopus 로고
    • FcgammaRIV is a mouse IgE receptor that resembles macrophage FcepsilonRI in humans and promotes IgE-induced lung inflammation
    • Mancardi DA, et al. (2008) FcgammaRIV is a mouse IgE receptor that resembles macrophage FcepsilonRI in humans and promotes IgE-induced lung inflammation. J Clin Invest 118:3738-3750.
    • (2008) J Clin Invest , vol.118 , pp. 3738-3750
    • Mancardi, D.A.1
  • 20
    • 73249132352 scopus 로고    scopus 로고
    • Both FcgammaRIV and FcgammaRIII are essential receptors mediating type II and type III autoimmune responses via FcRgamma-LAT-dependent generation of C5a
    • Syed SN, et al. (2009) Both FcgammaRIV and FcgammaRIII are essential receptors mediating type II and type III autoimmune responses via FcRgamma-LAT-dependent generation of C5a. Eur J Immunol 39:3343-3356.
    • (2009) Eur J Immunol , vol.39 , pp. 3343-3356
    • Syed, S.N.1
  • 21
    • 58849163199 scopus 로고    scopus 로고
    • Fc gamma RIII and Fc gamma RIV are indispensable for acute glomerular inflammation induced by switch variant monoclonal antibodies
    • Giorgini A, et al. (2008) Fc gamma RIII and Fc gamma RIV are indispensable for acute glomerular inflammation induced by switch variant monoclonal antibodies. J Immunol 181:8745-8752.
    • (2008) J Immunol , vol.181 , pp. 8745-8752
    • Giorgini, A.1
  • 22
    • 33645080442 scopus 로고    scopus 로고
    • Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors
    • Kaneko Y, Nimmerjahn F, Madaio MP, Ravetch JV (2006) Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors. J Exp Med 203:789-797.
    • (2006) J Exp Med , vol.203 , pp. 789-797
    • Kaneko, Y.1    Nimmerjahn, F.2    Madaio, M.P.3    Ravetch, J.V.4
  • 23
    • 0028042424 scopus 로고
    • FcR γ chain deletion results in pleiotrophic effector cell defects
    • DOI 10.1016/0092-8674(94)90115-5
    • Takai T, Li M, Sylvestre D, Clynes R, Ravetch JV (1994) FcR gamma chain deletion results in pleiotrophic effector cell defects. Cell 76:519-529. (Pubitemid 24064172)
    • (1994) Cell , vol.76 , Issue.3 , pp. 519-529
    • Takai, T.1    Li, M.2    Sylvestre, D.3    Clynes, R.4    Ravetch, J.V.5
  • 24
    • 0030615040 scopus 로고    scopus 로고
    • Absence of Fc epsilonRI alpha chain results in upregulation of Fc gammaRIII-dependent mast cell degranulation and anaphylaxis. Evidence of competition between Fc epsilonRI and Fc gammaRIII for limiting amounts of FcR beta and gamma chains
    • Dombrowicz D, et al. (1997) Absence of Fc epsilonRI alpha chain results in upregulation of Fc gammaRIII-dependent mast cell degranulation and anaphylaxis. Evidence of competition between Fc epsilonRI and Fc gammaRIII for limiting amounts of FcR beta and gamma chains. J Clin Invest 99:915-925.
    • (1997) J Clin Invest , vol.99 , pp. 915-925
    • Dombrowicz, D.1
  • 25
    • 0030458140 scopus 로고    scopus 로고
    • Immunoglobulin G-mediated inflammatory responses develop normally in complement-deficient mice
    • Sylvestre D, et al. (1996) Immunoglobulin G-mediated inflammatory responses develop normally in complement-deficient mice. J Exp Med 184:2385-2392.
    • (1996) J Exp Med , vol.184 , pp. 2385-2392
    • Sylvestre, D.1
  • 26
    • 0028059052 scopus 로고
    • Fc receptors initiate the Arthus reaction: Redefining the inflammatory cascade
    • Sylvestre DL, Ravetch JV (1994) Fc receptors initiate the Arthus reaction: Redefining the inflammatory cascade. Science 265:1095-1098.
    • (1994) Science , vol.265 , pp. 1095-1098
    • Sylvestre, D.L.1    Ravetch, J.V.2
  • 27
    • 18344365948 scopus 로고    scopus 로고
    • Arthritis critically dependent on innate immune system players
    • Ji H, et al. (2002) Arthritis critically dependent on innate immune system players. Immunity 16:157-168.
    • (2002) Immunity , vol.16 , pp. 157-168
    • Ji, H.1
  • 28
    • 0029669952 scopus 로고    scopus 로고
    • Reconstitution of human Fc gamma RIII cell type specificity in transgenic mice
    • Li M, Wirthmueller U, Ravetch JV (1996) Reconstitution of human Fc gamma RIII cell type specificity in transgenic mice. J Exp Med 183:1259-1263.
    • (1996) J Exp Med , vol.183 , pp. 1259-1263
    • Li, M.1    Wirthmueller, U.2    Ravetch, J.V.3
  • 29
    • 0033120914 scopus 로고    scopus 로고
    • The role of the human Fc receptor Fc gamma RIIA in the immune clearance of platelets: A transgenic mouse model
    • McKenzie SE, et al. (1999) The role of the human Fc receptor Fc gamma RIIA in the immune clearance of platelets: A transgenic mouse model. J Immunol 162:4311-4318.
    • (1999) J Immunol , vol.162 , pp. 4311-4318
    • McKenzie, S.E.1
  • 30
    • 0035910392 scopus 로고    scopus 로고
    • Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor
    • Samuelsson A, Towers TL, Ravetch JV (2001) Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor. Science 291:484-486.
    • (2001) Science , vol.291 , pp. 484-486
    • Samuelsson, A.1    Towers, T.L.2    Ravetch, J.V.3
  • 31
    • 0030273079 scopus 로고    scopus 로고
    • A dominant role for mast cell Fc receptors in the arthus reaction
    • Sylvestre DL, Ravetch JV (1996) A dominant role for mast cell Fc receptors in the Arthus reaction. Immunity 5:387-390.
    • (1996) Immunity , vol.5 , pp. 387-390
    • Sylvestre, D.L.1    Ravetch, J.V.2


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