Absence of Fc(ε)RI α chain results in upregulation of FcγRIII- dependent mast cell degranulation and anaphylaxis: Evidence of competition between Fc(ε)RI and FcγRIII for limiting amounts of FcR β and γ chains

Journal of Clinical Investigation

Volumn 99, Issue 5, 1997, Pages 915-925

  Dombrowicz, David ^a   Flamand, Véronique ^a   Miyajima, Ichiro ^b   Ravetch, Jeffrey V ^c   Galli, Stephen J ^b   Kinet, Jean Pierre ^b,d  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

allergy; asthma; Fc RI; IgE; passive cutaneous anaphylaxis

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1; ANTIBODY; HAPTEN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E RECEPTOR; IMMUNOGLOBULIN G; NITROBENZENE DERIVATIVE;

ANAPHYLAXIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; MALE; MAST CELL DEGRANULATION; MOUSE; NONHUMAN; PASSIVE SKIN ANAPHYLAXIS; PRIORITY JOURNAL; ANIMAL; BAGG ALBINO MOUSE; BONE MARROW CELL; C57BL MOUSE; CELL CULTURE; DEGRANULATION; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; MAST CELL; METABOLISM; MOUSE MUTANT; PATHOPHYSIOLOGY; PHYSIOLOGY; UPREGULATION;

ANAPHYLAXIS; ANIMALS; ANTIBODIES; BODY TEMPERATURE; BONE MARROW CELLS; CELL DEGRANULATION; CELLS, CULTURED; DINITROBENZENES; FEMALE; GENE EXPRESSION REGULATION; HAPTENS; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; MALE; MAST CELLS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, MUTANT STRAINS; PASSIVE CUTANEOUS ANAPHYLAXIS; RECEPTORS, IGE; RECEPTORS, IGG; UP-REGULATION;

EID: 0030615040     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119256     Document Type: Article

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