The glypican 3-hosted murine Mir717 gene: Sequence conservation, seed region polymorphisms and putative targets

International Journal of Biological Sciences

Volumn 6, Issue 7, 2010, Pages 769-772

  Kunej, Tanja ^a   Skok, Dasa Jevsinek ^a   Horvat, Simon ^a,b   Dovc, Peter ^a   Jiang, Zhihua ^c  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

^c WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Comparative genomics; Glypican 3 (Gpc3) gene; MicroRNA (miRNA); Mir717 (mmu miR 717); Obesity

Indexed keywords

MAMMALIA; MURINAE; MUS;

EID: 78650557277     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.6.769     Document Type: Article

References (19)

1. Huang W, Liu H, Wang T, et al. Tonicity-responsive micro- RNAs contribute to the maximal induction of osmoregulatory transcription factor OREBP in response to high-NaCl hypertonicity. Nucleic Acids Res. 2010; [Epub ahead of print].
2. Baskerville S and Bartel DP. Microarray profiling of micro- RNAs reveals frequent coexpression with neighboring miRNAs and host genes. RNA. 2005; 11: 241-7.
3. Li SC, Tang P, Lin WC. Intronic microRNA: discovery and biological implications. DNA Cell Biol. 2007; 26: 195-207.
4. Polster BJ, Westaway SK, Nguyen TM, et al. Discordant expression of miR-103/7 and pantothenate kinase host genes in mouse. Mol Genet Metab. 2010; 101: 292-5.
5. Pilia G, Hughes-Benzie RM, MacKenzie A, et al. Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome. Nat Genet. 1996; 12: 241-7.
6. Cano-Gauci DF, Song HH, Yang HL, et al. Glypican-3-deficient mice exhibit developmental overgrowth and some of the abnormalities typical of Simpson-Golabi-Behmel syndrome. J Cell Biol. 1999; 146: 255-64.
7. Oliver F, Christians JK, Liu X, et al. Regulatory variation at glypican-3 underlies a major growth QTL in mice. PLoS Biol. 2005; 3: 872-7.
8. Rozman D., McWhir J., Horvat S. Defects in cholesterol synthesis genes in mouse and in humans: lessons for drug development and safer treatments. Drug Metab Rev; in press.
9. Horvat S and Medrano JF. Lack of Socs2 expression causes the high-growth phenotype in mice. Genomics. 2001; 72: 209-12.
10. Magin TM, McWhir J, Melton DW. A new mouse embryonic stem-cell line with good germ line contribution and gene targeting frequency. Nucleic Acids Res. 1992; 20: 3795-6.
11. Sun G, Yan J, Noltner K, et al. SNPs in human miRNA genes affect biogenesis and function. RNA. 2009; 15: 1640-51.
12. Nicoloso MS, Sun H, Spizzo R, et al. Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility. Cancer Res. 2010; 70: 2789-98.
13. Mencía A, Modamio-Høybjør S, Redshaw N, et al. Mutations in the seed region of human miR-96 are responsible for nonsyndromic progressive hearing loss. Nat Genet. 2009; 41: 609-13.
14. Lewis MA, Quint E, Glazier AM, et al. An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice. Nat Genet. 2009; 41: 614-8.
15. Rankinen T, Zuberi A, Chagnon YC, et al. The human obesity gene map: the 2005 update. Obesity (Silver Spring). 2006; 14: 529-44.
16. Lin Q, Gao Z, Alarcon RM, et al. A role of miR-27 in the regulation of adipogenesis. FEBS J. 2009; 276: 2348-58.
17. Kim YJ, Hwang SJ, Bae YC, et al. MiR-21 regulates adipogenic differentiation through the modulation of TGF-beta signaling in mesenchymal stem cells derived from human adipose tissue. Stem Cells. 2009; 27: 3093-102.
18. Karbiener M, Fischer C, Nowitsch S, et al. microRNA miR-27b impairs human adipocyte differentiation and targets PPARgamma. Biochem Biophys Res Commun. 2009; 390: 247-51.
19. Nakanishi N, Nakagawa Y, Tokushige N, et al. The up-regulation of microRNA-335 is associated with lipid metabolism in liver and white adipose tissue of genetically obese mice. Biochem Biophys Res Commun. 2009; 385: 492-6.