TRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 47, 2010, Pages 20305-20310

  Hyde, Samantha J ^a   Eckenroth, Brian E ^a   Smith, Brian A ^b,c   Eberley, William A ^b   Heintz, Nicholas H ^a,d   Jackman, Jane E ^b,c   Doublié, Sylvie ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b Department of Biochemistry and Center for RNA Biology ^*  (United States)

^c OHIO STATE UNIVERSITY   (United States)

^d UNIVERSITY OF VERMONT   (United States)

Author keywords

G 1 addition; Reverse polymerase; TRNA modification

Indexed keywords

ADENYLATE CYCLASE; DNA POLYMERASE; GUANYLYLCYCLASE; MAGNESIUM; METAL ION; NUCLEIC ACID; NUCLEOTIDE; NUCLEOTIDYLTRANSFERASE; TRANSFER RNA HISTIDINE GUANYLYLTRANSFERASE; TRANSFERASE; UNCLASSIFIED DRUG;

ADENYLATION; CATALYSIS; CONFERENCE PAPER; CRYSTAL STRUCTURE; ENZYME BINDING; ENZYME STRUCTURE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STRUCTURAL HOMOLOGY; STRUCTURE ANALYSIS;

EID: 78650524780     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1010436107     Document Type: Article

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