Screening of thiourea derivatives and carbonyl-2-aminothiazole derivatives for potential CCR4 antagonists using capillary zone electrophoresis

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 879, Issue 1, 2011, Pages 75-82

  Zhang, Shuyu ^a   Qi, Hui ^a   Yakufu, Pazilaiti ^a   Zhao, Fang ^a   Ling, Xiaomei ^a   Xiao, Junhai ^b   Wang, Ying ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

Author keywords

C arbonyl 2 aminothiazole derivatives; Capillary zone electrophoresis; CCR4 antagonists interactions; Thiourea derivatives

Indexed keywords

2-AMINOTHIAZOLES; [CARBONYL; ANALYTICAL METHOD; BINDING CONSTANT; C-ARBONYL-2-AMINOTHIAZOLE DERIVATIVES; CAPILLARY ZONE ELECTROPHORESIS; CCR4 ANTAGONISTS/INTERACTIONS; CHEMOKINE RECEPTORS; DRUG TARGETS; FAST SCREENING; G PROTEIN COUPLED RECEPTORS; INFLAMMATORY DISEASE; N-TERMINALS; NOVEL SERIES; PEPTIDE BINDING; QUANTITATIVE CHARACTERIZATION; SCATCHARD PLOTS; T CELLS; THIOUREA DERIVATIVES; TRANSMEMBRANE STRUCTURE;

CAPILLARY ELECTROPHORESIS; DISEASES; PEPTIDES; THIOUREAS; UREA;

ELECTROCHEMISTRY;

2 AMINOTHIAZOLE DERIVATIVE; CHEMOKINE RECEPTOR CCR ANTAGONIST; CHEMOKINE RECEPTOR CCR4; THIOUREA DERIVATIVE;

ARTICLE; BINDING AFFINITY; CAPILLARY ZONE ELECTROPHORESIS; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INFLAMMATORY DISEASE; PRIORITY JOURNAL; PROTEIN BINDING; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SCATCHARD PLOT; TH2 CELL;

ELECTROPHORESIS, CAPILLARY; HUMANS; PROTEIN BINDING; RECEPTORS, CCR4; REGRESSION ANALYSIS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; THIAZOLES; THIOUREA;

EID: 78650522845     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2010.11.014     Document Type: Article

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