-
2
-
-
0037205048
-
The phosphoinositide 3-kinase pathway
-
Cantley L.C. The phosphoinositide 3-kinase pathway. Science 2002, 296:1655-1657.
-
(2002)
Science
, vol.296
, pp. 1655-1657
-
-
Cantley, L.C.1
-
3
-
-
0041198092
-
Andrographolide, the active constituent of Andrographis paniculata Nees; a preliminary communication
-
Chakravarti R.N., Chakravarti D. Andrographolide, the active constituent of Andrographis paniculata Nees; a preliminary communication. Ind. Med. Gaz. 1951, 86:96-97.
-
(1951)
Ind. Med. Gaz.
, vol.86
, pp. 96-97
-
-
Chakravarti, R.N.1
Chakravarti, D.2
-
4
-
-
0031756640
-
An in vivo model for elucidation of the mechanism of tumor necrosis factor-alpha (TNF-alpha)-induced insulin resistance: evidence for differential regulation of insulin signaling by TNF-alpha
-
Cheung A.T., Ree D., Kolls J.K., Fuselier J., Coy D.H., Bryer-Ash M. An in vivo model for elucidation of the mechanism of tumor necrosis factor-alpha (TNF-alpha)-induced insulin resistance: evidence for differential regulation of insulin signaling by TNF-alpha. Endocrinology 1998, 139:4928-4935.
-
(1998)
Endocrinology
, vol.139
, pp. 4928-4935
-
-
Cheung, A.T.1
Ree, D.2
Kolls, J.K.3
Fuselier, J.4
Coy, D.H.5
Bryer-Ash, M.6
-
5
-
-
0034049447
-
The role of tumour necrosis factor (TNF)-alpha resistance in obesity and insulin resistance
-
Cseh K., Winkler G., Melczer Z., Baranyi E. The role of tumour necrosis factor (TNF)-alpha resistance in obesity and insulin resistance. Diabetologia 2000, 43:525.
-
(2000)
Diabetologia
, vol.43
, pp. 525
-
-
Cseh, K.1
Winkler, G.2
Melczer, Z.3
Baranyi, E.4
-
6
-
-
0027332738
-
Tumor necrosis factor-alpha suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrates
-
Feinstein R., Kanety H., Papa M.Z., Lunenfeld B., Karasik A. Tumor necrosis factor-alpha suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrates. J. Biol. Chem. 1993, 268:26055-26058.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 26055-26058
-
-
Feinstein, R.1
Kanety, H.2
Papa, M.Z.3
Lunenfeld, B.4
Karasik, A.5
-
7
-
-
47149096915
-
Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity
-
Heilbronn L.K., Campbell L.V. Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity. Curr. Pharm. Des. 2008, 14:1225-1230.
-
(2008)
Curr. Pharm. Des.
, vol.14
, pp. 1225-1230
-
-
Heilbronn, L.K.1
Campbell, L.V.2
-
8
-
-
15944409586
-
Andrographolide interferes with binding of nuclear factor-kappaB to DNA in HL-60-derived neutrophilic cells
-
Hidalgo M.A., Romero A., Figueroa J., Cortes P., Concha I.I., Hancke J.L., Burgos R.A. Andrographolide interferes with binding of nuclear factor-kappaB to DNA in HL-60-derived neutrophilic cells. Br. J. Pharmacol. 2005, 144:680-686.
-
(2005)
Br. J. Pharmacol.
, vol.144
, pp. 680-686
-
-
Hidalgo, M.A.1
Romero, A.2
Figueroa, J.3
Cortes, P.4
Concha, I.I.5
Hancke, J.L.6
Burgos, R.A.7
-
9
-
-
0030061922
-
IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
-
Hotamisligil G.S., Peraldi P., Budavari A., Ellis R., White M.F., Spiegelman B.M. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 1996, 271:665-668.
-
(1996)
Science
, vol.271
, pp. 665-668
-
-
Hotamisligil, G.S.1
Peraldi, P.2
Budavari, A.3
Ellis, R.4
White, M.F.5
Spiegelman, B.M.6
-
10
-
-
0032925340
-
Mechanisms of TNF-alpha-induced insulin resistance
-
Hotamisligil G.S. Mechanisms of TNF-alpha-induced insulin resistance. Exp. Clin. Endocrinol. Diabetes 1999, 107:119-125.
-
(1999)
Exp. Clin. Endocrinol. Diabetes
, vol.107
, pp. 119-125
-
-
Hotamisligil, G.S.1
-
11
-
-
21344460247
-
An immune origin of type 2 diabetes?
-
Kolb H., Mandrup-Poulsen T. An immune origin of type 2 diabetes?. Diabetologia 2005, 48:1038-1050.
-
(2005)
Diabetologia
, vol.48
, pp. 1038-1050
-
-
Kolb, H.1
Mandrup-Poulsen, T.2
-
13
-
-
0031892271
-
TNF-alpha and insulin resistance: summary and future prospects
-
Peraldi P., Spiegelman B. TNF-alpha and insulin resistance: summary and future prospects. Mol. Cell. Biochem. 1998, 182:169-175.
-
(1998)
Mol. Cell. Biochem.
, vol.182
, pp. 169-175
-
-
Peraldi, P.1
Spiegelman, B.2
-
14
-
-
0031720795
-
Is type II diabetes mellitus a disease of the innate immune system?
-
Pickup J.C., Crook M.A. Is type II diabetes mellitus a disease of the innate immune system?. Diabetologia 1998, 41:1241-1248.
-
(1998)
Diabetologia
, vol.41
, pp. 1241-1248
-
-
Pickup, J.C.1
Crook, M.A.2
-
15
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
Saltiel A.R., Kahn C.R. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 2001, 414:799-806.
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
16
-
-
46749119448
-
In vitro alpha-glucosidase and alpha-amylase enzyme inhibitory effects of Andrographis paniculata extract and andrographolide
-
Subramanian R., Asmawi M.Z., Sadikun A. In vitro alpha-glucosidase and alpha-amylase enzyme inhibitory effects of Andrographis paniculata extract and andrographolide. Acta Biochim. Pol. 2008, 55:391-398.
-
(2008)
Acta Biochim. Pol.
, vol.55
, pp. 391-398
-
-
Subramanian, R.1
Asmawi, M.Z.2
Sadikun, A.3
-
17
-
-
72549092079
-
Antinociceptive and Antiedematogenic Activities of Andrographolide Isolated From Andrographis paniculata in Animal Models
-
Sulaiman M.R., Zakaria Z.A., Abdul Rahman A., Mohamad A.S., Desa M.N., Stanslas J., Moin S., Israf D.A. Antinociceptive and Antiedematogenic Activities of Andrographolide Isolated From Andrographis paniculata in Animal Models. Biol. Res. Nurs. 2010, 11:293-301.
-
(2010)
Biol. Res. Nurs.
, vol.11
, pp. 293-301
-
-
Sulaiman, M.R.1
Zakaria, Z.A.2
Abdul Rahman, A.3
Mohamad, A.S.4
Desa, M.N.5
Stanslas, J.6
Moin, S.7
Israf, D.A.8
-
19
-
-
34548136987
-
Hepatoprotective effect of andrographolide against hexachlorocyclohexane-induced oxidative injury
-
Trivedi N.P., Rawal U.M., Patel B.P. Hepatoprotective effect of andrographolide against hexachlorocyclohexane-induced oxidative injury. Integr. Cancer Ther. 2007, 6:271-280.
-
(2007)
Integr. Cancer Ther.
, vol.6
, pp. 271-280
-
-
Trivedi, N.P.1
Rawal, U.M.2
Patel, B.P.3
-
21
-
-
4644241127
-
Andrographolide attenuates inflammation by inhibition of NF-kappa B activation through covalent modification of reduced cysteine 62 of p50
-
Xia Y.F., Ye B.Q., Li Y.D., Wang J.G., He X.J., Lin X., Yao X., Ma D., Slungaard A., Hebbel R.P., Key N.S., Geng J.G. Andrographolide attenuates inflammation by inhibition of NF-kappa B activation through covalent modification of reduced cysteine 62 of p50. J. Immunol. 2004, 173:4207-4217.
-
(2004)
J. Immunol.
, vol.173
, pp. 4207-4217
-
-
Xia, Y.F.1
Ye, B.Q.2
Li, Y.D.3
Wang, J.G.4
He, X.J.5
Lin, X.6
Yao, X.7
Ma, D.8
Slungaard, A.9
Hebbel, R.P.10
Key, N.S.11
Geng, J.G.12
-
22
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu H., Barnes G.T., Yang Q., Tan G., Yang D., Chou C.J., Sole J., Nichols A., Ross J.S., Tartaglia L.A., Chen H. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest. 2003, 112:1821-1830.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
23
-
-
1242329231
-
Antihyperglycemic effect of andrographolide in streptozotocin-induced diabetic rats
-
Yu B.C., Hung C.R., Chen W.C., Cheng J.T. Antihyperglycemic effect of andrographolide in streptozotocin-induced diabetic rats. Planta Med. 2003, 69:1075-1079.
-
(2003)
Planta Med.
, vol.69
, pp. 1075-1079
-
-
Yu, B.C.1
Hung, C.R.2
Chen, W.C.3
Cheng, J.T.4
-
24
-
-
45849092979
-
Mediation of beta-endorphin in andrographolide-induced plasma glucose-lowering action in type I diabetes-like animals
-
Yu B.C., Chang C.K., Su C.F., Cheng J.T. Mediation of beta-endorphin in andrographolide-induced plasma glucose-lowering action in type I diabetes-like animals. Naunyn Schmiedebergs Arch. Pharmacol. 2008, 377:529-540.
-
(2008)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.377
, pp. 529-540
-
-
Yu, B.C.1
Chang, C.K.2
Su, C.F.3
Cheng, J.T.4
-
25
-
-
68349146183
-
Hypoglycemic and beta cell protective effects of andrographolide analogue for diabetes treatment
-
Zhang Z., Jiang J., Yu P., Zeng X., Larrick J.W., Wang Y. Hypoglycemic and beta cell protective effects of andrographolide analogue for diabetes treatment. J. Transl. Med. 2009, 7:62.
-
(2009)
J. Transl. Med.
, vol.7
, pp. 62
-
-
Zhang, Z.1
Jiang, J.2
Yu, P.3
Zeng, X.4
Larrick, J.W.5
Wang, Y.6
-
26
-
-
51049122623
-
Andrographolide sensitizes cancer cells to TRAIL-induced apoptosis via p53-mediated death receptor 4 up-regulation
-
Zhou J., Lu G.D., Ong C.S., Ong C.N., Shen H.M. Andrographolide sensitizes cancer cells to TRAIL-induced apoptosis via p53-mediated death receptor 4 up-regulation. Mol. Cancer Ther. 2008, 7:2170-2180.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 2170-2180
-
-
Zhou, J.1
Lu, G.D.2
Ong, C.S.3
Ong, C.N.4
Shen, H.M.5
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