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Volumn 31, Issue 6, 2010, Pages 741-749

Serotonin transporter and saitohin genes in risk of Alzheimer's disease and frontotemporal lobar dementia: Preliminary findings

Author keywords

Case control study; Dementia; Genetics; Saitohin; Serotonin; Serotonin transporter

Indexed keywords

SAITOHIN; SEROTONIN TRANSPORTER; TAU PROTEIN; UNCLASSIFIED DRUG;

EID: 78650517131     PISSN: 15901874     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10072-010-0400-8     Document Type: Article
Times cited : (12)

References (77)
  • 1
    • 27944508290 scopus 로고    scopus 로고
    • Neuropsychological differences between frontotemporal dementia and Alzheimer's disease: A review
    • DOI 10.1007/s11065-005-7093-4
    • M Harciarek K Jodzio 2005 Neuropsychological differences between frontotemporal dementia and Alzheimer's disease: a review Neuropsychol Rev 15 131 145 10.1007/s11065-005-7093-4 16328732 (Pubitemid 41674441)
    • (2005) Neuropsychology Review , vol.15 , Issue.3 , pp. 131-145
    • Harciarek, M.1    Jodzio, K.2
  • 4
    • 33750368880 scopus 로고    scopus 로고
    • Dysregulation of tau phosphorylation is a hypothesized point of convergence in the pathogenesis of alzheimer's disease, frontotemporal dementia and schizophrenia with therapeutic implications
    • DOI 10.1016/j.pnpbp.2006.04.007, PII S027858460600162X
    • SI Deutsch RB Rosse RM Lakshman 2006 Dysregulation of tau phosphorylation is a hypothesized point of convergence in the pathogenesis of Alzheimer's disease, frontotemporal dementia and schizophrenia with therapeutic implications Prog Neuropsychopharmacol Biol Psychiatry 30 1369 1380 10.1016/j.pnpbp.2006.04. 007 16793187 (Pubitemid 44634940)
    • (2006) Progress in Neuro-Psychopharmacology and Biological Psychiatry , vol.30 , Issue.8 , pp. 1369-1380
    • Deutsch, S.I.1    Rosse, R.B.2    Lakshman, R.M.3
  • 5
    • 0003374626 scopus 로고    scopus 로고
    • Tau protein pathology in neurodegenerative diseases
    • DOI 10.1016/S0166-2236(98)01337-X
    • MG Spillantini M Goedert 1998 Tau protein pathology in neurodegenerative diseases Trends Neurosci 21 428 433 10.1016/S0166-2236(98)01337-X 9786340 (Pubitemid 28449072)
    • (1998) Trends in Neurosciences , vol.21 , Issue.10 , pp. 428-433
    • Spillantini, M.G.1    Goedert, M.2
  • 6
    • 0022744803 scopus 로고
    • Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology
    • 10.1073/pnas.83.13.4913 3088567
    • I Grundke-Iqbal K Iqbal YC Tung M Quinlan HM Wisniewski LI Binder 1986 Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology Proc Natl Acad Sci USA 83 4913 4917 10.1073/pnas.83.13.4913 3088567
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 4913-4917
    • Grundke-Iqbal, I.1    Iqbal, K.2    Tung, Y.C.3    Quinlan, M.4    Wisniewski, H.M.5    Binder, L.I.6
  • 7
    • 0030748390 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons
    • DOI 10.1074/jbc.272.31.19547
    • M Hong VM Lee 1997 Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons J Biol Chem 272 19547 19553 10.1074/jbc.272.31.19547 9235959 (Pubitemid 27337756)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.31 , pp. 19547-19553
    • Hong, M.1    Lee, V.M.-Y.2
  • 8
    • 0030868557 scopus 로고    scopus 로고
    • Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3
    • DOI 10.1074/jbc.272.40.25326
    • M Hong DC Chen PS Klein VM Lee 1997 Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3 J Biol Chem 272 25326 25332 10.1074/jbc.272.40.25326 9312151 (Pubitemid 27415724)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.40 , pp. 25326-25332
    • Hong, M.1    Chen, D.C.R.2    Klein, P.S.3    Lee, V.M.-Y.4
  • 10
    • 0034764622 scopus 로고    scopus 로고
    • Clinical and pathological diagnosis of frontotemporal dementia: Report of the Work Group on Frontotemporal Dementia and Pick's Disease
    • 10.1001/archneur.58.11.1803 11708987
    • GM McKhann MS Albert M Grossman B Miller D Dickson JQ Trojanowski 2001 Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease Arch Neurol 58 1803 1809 10.1001/archneur.58.11.1803 11708987
    • (2001) Arch Neurol , vol.58 , pp. 1803-1809
    • McKhann, G.M.1    Albert, M.S.2    Grossman, M.3    Miller, B.4    Dickson, D.5    Trojanowski, J.Q.6
  • 12
    • 3042558276 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3: A drug target for CNS therapies
    • DOI 10.1111/j.1471-4159.2004.02422.x
    • RV Bhat SL Budd Haeberlein J Avila 2004 Glycogen synthase kinase 3: a drug target for CNS therapies J Neurochem 89 1313 1317 10.1111/j.1471-4159.2004. 02422.x 15189333 (Pubitemid 38802652)
    • (2004) Journal of Neurochemistry , vol.89 , Issue.6 , pp. 1313-1317
    • Bhat, R.V.1    Budd Haeberlein, S.L.2    Avila, J.3
  • 13
    • 24344457727 scopus 로고    scopus 로고
    • The evolution and pathology of frontotemporal dementia
    • DOI 10.1093/brain/awh598
    • A Kertesz P McMonagle M Blair W Davidson DG Munoz 2005 The evolution and pathology of frontotemporal dementia Brain 128 1996 2005 10.1093/brain/awh598 16033782 (Pubitemid 41253267)
    • (2005) Brain , vol.128 , Issue.9 , pp. 1996-2005
    • Kertesz, A.1    McMonagle, P.2    Blair, M.3    Davidson, W.4    Munoz, D.G.5
  • 15
    • 52449089987 scopus 로고    scopus 로고
    • Thirty years of Alzheimer's disease genetics: The implications of systematic meta-analyses
    • 10.1038/nrn2494 18802446
    • L Bertram RE Tanzi 2008 Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses Nat Rev Neurosci 9 768 778 10.1038/nrn2494 18802446
    • (2008) Nat Rev Neurosci , vol.9 , pp. 768-778
    • Bertram, L.1    Tanzi, R.E.2
  • 16
    • 35448970651 scopus 로고    scopus 로고
    • The molecular genetics and neuropathology of frontotemporal lobar degeneration: Recent developments
    • DOI 10.1007/s10048-007-0102-4
    • IR Mackenzie R Rademakers 2007 The molecular genetics and neuropathology of frontotemporal lobar degeneration: recent developments Neurogenetics 8 237 248 10.1007/s10048-007-0102-4 17805587 (Pubitemid 47624449)
    • (2007) Neurogenetics , vol.8 , Issue.4 , pp. 237-248
    • Mackenzie, I.R.A.1    Rademakers, R.2
  • 19
    • 0032965787 scopus 로고    scopus 로고
    • Mutation in the tau exon 10 splice site region in familial frontotemporal dementia [1]
    • DOI 10.1002/1531-8249(199902)45:2<270::AID-ANA22>3.0.CO;2-2
    • HR Morris J Perez-Tur JC Janssen J Brown AJ Lees NW Wood J Hardy M Hutton MN Rossor 1999 Mutation in the tau exon 10 splice site region in familial frontotemporal dementia Ann Neurol 45 270 271 10.1002/1531-8249(199902)45: 2<270::AID-ANA22>3.0.CO;2-2 9989634 (Pubitemid 29072380)
    • (1999) Annals of Neurology , vol.45 , Issue.2 , pp. 270-271
    • Morris, H.R.1    Perez-Tur, J.2    Janssen, J.C.3    Brown, J.4    Lees, A.J.5    Wood, N.W.6    Hardy, J.7    Hutton, M.8    Rossor, M.N.9
  • 21
    • 5044235577 scopus 로고    scopus 로고
    • The role of tau (MAPT) in frontotemporal dementia and related tauopathies
    • DOI 10.1002/humu.20086
    • R Rademakers M Cruts C van Broeckhoven 2004 The role of tau (MAPT) in frontotemporal dementia and related tauopathies Hum Mutat 24 277 295 10.1002/humu.20086 15365985 (Pubitemid 39336634)
    • (2004) Human Mutation , vol.24 , Issue.4 , pp. 277-295
    • Rademakers, R.1    Cruts, M.2    Van Broeckhoven, C.3
  • 22
    • 0023881790 scopus 로고
    • Possible neurotransmitter basis of behavioral changes in Alzheimer's disease
    • 10.1002/ana.410230616 2457353
    • AM Palmer GC Stratmann AW Procter DM Bowen 1988 Possible neurotransmitter basis of behavioral changes in Alzheimer's disease Ann Neurol 23 616 620 10.1002/ana.410230616 2457353
    • (1988) Ann Neurol , vol.23 , pp. 616-620
    • Palmer, A.M.1    Stratmann, G.C.2    Procter, A.W.3    Bowen, D.M.4
  • 23
    • 0025651974 scopus 로고
    • Neurotransmitter changes in Alzheimer's disease: Implications to diagnostics and therapy
    • 10.1002/jnr.490270419 1981917
    • KJ Reinikainen H Soininen PJ Riekkinen 1990 Neurotransmitter changes in Alzheimer's disease: implications to diagnostics and therapy J Neurosci Res 27 576 586 10.1002/jnr.490270419 1981917
    • (1990) J Neurosci Res , vol.27 , pp. 576-586
    • Reinikainen, K.J.1    Soininen, H.2    Riekkinen, P.J.3
  • 25
    • 0029584664 scopus 로고
    • Serotonin uptake and its kinetics in platelets of women with Alzheimer's disease
    • DOI 10.1016/0165-1781(95)02786-6
    • AM Kumar M Kumar S Sevush J Ruiz C Eisdorfer 1995 Serotonin uptake and its kinetics in platelets of women with Alzheimer's disease Psychiatry Res 59 145 150 10.1016/0165-1781(95)02786-6 8771229 (Pubitemid 26024511)
    • (1995) Psychiatry Research , vol.59 , Issue.1-2 , pp. 145-150
    • Kumar, A.M.1
  • 27
    • 0029895783 scopus 로고    scopus 로고
    • Allelic variation of human serotonin transporter gene expression
    • 10.1046/j.1471-4159.1996.66062621.x 8632190
    • A Heils A Teufel S Petri G Stöber P Riederer D Bengel P Lesch 1996 Allelic variation of human serotonin transporter gene expression J Neurochem 66 2621 2624 10.1046/j.1471-4159.1996.66062621.x 8632190
    • (1996) J Neurochem , vol.66 , pp. 2621-2624
    • Heils, A.1    Teufel, A.2    Petri, S.3    Stöber, G.4    Riederer, P.5    Bengel, D.6    Lesch, P.7
  • 29
    • 14444278967 scopus 로고    scopus 로고
    • Allelic functional variation of serotonin transporter expression is a susceptibility factor for late onset Alzheimer's disease
    • 10.1097/00001756-199702100-00021 9106747
    • T Li C Holmes PC Sham H Vallada J Birkett G Kirov KP Lesch J Powell S Lovestone D Collier 1997 Allelic functional variation of serotonin transporter expression is a susceptibility factor for late onset Alzheimer's disease Neuroreport 8 683 686 10.1097/00001756-199702100-00021 9106747
    • (1997) Neuroreport , vol.8 , pp. 683-686
    • Li, T.1    Holmes, C.2    Sham, P.C.3    Vallada, H.4    Birkett, J.5    Kirov, G.6    Lesch, K.P.7    Powell, J.8    Lovestone, S.9    Collier, D.10
  • 30
    • 0033111860 scopus 로고    scopus 로고
    • The study of genetic polymorphisms related to serotonin in Alzheimer's disease: New perspective in a heterogenic disorder
    • 10347811
    • JRM Oliveira M Zatz 1999 The study of genetic polymorphisms related to serotonin in Alzheimer's disease: new perspective in a heterogenic disorder Braz J Med Biol Res 32 463 467 10347811
    • (1999) Braz J Med Biol Res , vol.32 , pp. 463-467
    • Oliveira, J.R.M.1    Zatz, M.2
  • 31
    • 0031663853 scopus 로고    scopus 로고
    • The short variant of the polymorphism within the promoter region of the serotonin transporter gene is a risk factor for late onset Alzheimers-disease
    • 10.1038/sj.mp.4000417 9774779
    • JRM Oliveira RM Gallindo LGS Maia PR Britomarques PA Otto MR Passosbueno MA Morais M Zatz 1998 The short variant of the polymorphism within the promoter region of the serotonin transporter gene is a risk factor for late onset Alzheimers-disease Mol Psychiatry 3 438 441 10.1038/sj.mp.4000417 9774779
    • (1998) Mol Psychiatry , vol.3 , pp. 438-441
    • Oliveira, J.R.M.1    Gallindo, R.M.2    Maia, L.G.S.3    Britomarques, P.R.4    Otto, P.A.5    Passosbueno, M.R.6    Morais, M.A.7    Zatz, M.8
  • 33
    • 4043174258 scopus 로고    scopus 로고
    • Association of the serotonin transporter and receptor gene polymorphisms in neuropsychiatric symptoms in Alzheimer disease
    • DOI 10.1001/archneur.61.8.1249
    • F Assal M Alarcon EC Solomon D Masterman DH Geschwind JL Cummings V Klimek G Roberson CA Stockmeier GA Ordway 2004 Association of the serotonin transporter and receptor gene polymorphisms in neuropsychiatric symptoms in Alzheimer disease Arch Neurol 61 1249 1253 10.1001/archneur.61.8.1249 15313842 (Pubitemid 39062679)
    • (2004) Archives of Neurology , vol.61 , Issue.8 , pp. 1249-1253
    • Assal, F.1    Alarcon, M.2    Solomon, E.C.3    Masterman, D.4    Geschwind, D.H.5    Cummings, J.L.6
  • 36
    • 33645789852 scopus 로고    scopus 로고
    • Cumulative effect of COMT and 5-HTTLPR polymorphisms and their interaction with disease severity and comorbidities on the risk of psychosis in Alzheimer disease
    • 10.1097/01.JGP.0000192491.50802.c3 16582043
    • B Borroni M Grassi C Agosti S Archetti C Costanzi C Cornali C Caltagirone L Caimi M Di Luca A Padovani 2006 Cumulative effect of COMT and 5-HTTLPR polymorphisms and their interaction with disease severity and comorbidities on the risk of psychosis in Alzheimer disease Am J Geriatr Psychiatry 14 343 351 10.1097/01.JGP.0000192491.50802.c3 16582043
    • (2006) Am J Geriatr Psychiatry , vol.14 , pp. 343-351
    • Borroni, B.1    Grassi, M.2    Agosti, C.3    Archetti, S.4    Costanzi, C.5    Cornali, C.6    Caltagirone, C.7    Caimi, L.8    Di Luca, M.9    Padovani, A.10
  • 40
    • 0034634741 scopus 로고    scopus 로고
    • Promoter polymorphism of the 5-HT transporter and Alzheimer's disease
    • 10.1016/S0304-3940(00)01544-5 11044587
    • M Hu W Retz M Baader B Pesold G Adler FA Henn M Rosler J Thome 2000 Promoter polymorphism of the 5-HT transporter and Alzheimer's disease Neurosci Lett 294 63 65 10.1016/S0304-3940(00)01544-5 11044587
    • (2000) Neurosci Lett , vol.294 , pp. 63-65
    • Hu, M.1    Retz, W.2    Baader, M.3    Pesold, B.4    Adler, G.5    Henn, F.A.6    Rosler, M.7    Thome, J.8
  • 41
    • 23944435890 scopus 로고    scopus 로고
    • Genes involved in Alzheimer's disease, a survey of possible candidates
    • 16131736
    • A Serretti P Artioli R Quartesan D De Ronchi 2005 Genes involved in Alzheimer's disease, a survey of possible candidates J Alzheimers Dis 7 331 353 16131736
    • (2005) J Alzheimers Dis , vol.7 , pp. 331-353
    • Serretti, A.1    Artioli, P.2    Quartesan, R.3    De Ronchi, D.4
  • 43
    • 0033850407 scopus 로고    scopus 로고
    • Tau protein isoforms, phosphorylation and role in neurodegenerative disorders
    • 10.1016/S0165-0173(00)00019-9 10967355
    • L Buee T Bussiere V Buee-Scherrer A Delacourte PR Hof 2000 Tau protein isoforms, phosphorylation and role in neurodegenerative disorders Brain Res Brain Res Rev 33 95 130 10.1016/S0165-0173(00)00019-9 10967355
    • (2000) Brain Res Brain Res Rev , vol.33 , pp. 95-130
    • Buee, L.1    Bussiere, T.2    Buee-Scherrer, V.3    Delacourte, A.4    Hof, P.R.5
  • 44
    • 0036828831 scopus 로고    scopus 로고
    • No evidence for an association between saitohin Q7R polymorphism and Alzheimer's disease
    • 10.1002/ana.10362 12402275
    • L Cook CE Brayne D Easton JG Evans J Xuereb NJ Cairns DC Rubinsztein 2002 No evidence for an association between saitohin Q7R polymorphism and Alzheimer's disease Ann Neurol 52 690 691 10.1002/ana.10362 12402275
    • (2002) Ann Neurol , vol.52 , pp. 690-691
    • Cook, L.1    Brayne, C.E.2    Easton, D.3    Evans, J.G.4    Xuereb, J.5    Cairns, N.J.6    Rubinsztein, D.C.7
  • 46
  • 49
    • 1842457770 scopus 로고    scopus 로고
    • Molecular evolution and genetics of the saitohin gene and tau haplotype in Alzheimer's disease and argyrophilic grain disease
    • 10.1046/j.1471-4159.2004.02320.x 15030402
    • C Conrad C Vianna C Schultz DR Thal E Ghebremedhin J Lenz H Braak P Davies 2004 Molecular evolution and genetics of the saitohin gene and tau haplotype in Alzheimer's disease and argyrophilic grain disease J Neurochem 89 179 188 10.1046/j.1471-4159.2004.02320.x 15030402
    • (2004) J Neurochem , vol.89 , pp. 179-188
    • Conrad, C.1    Vianna, C.2    Schultz, C.3    Thal, D.R.4    Ghebremedhin, E.5    Lenz, J.6    Braak, H.7    Davies, P.8
  • 51
    • 44649109541 scopus 로고    scopus 로고
    • Genetic analysis of tumor necrosis factor-alpha (TNF-alpha) G-308A and saitohin Q7R polymorphisms with Alzheimer's disease
    • 10.1016/j.jns.2008.02.021 18396294
    • B Wang S Zhou Z Yang YC Xie J Wang P Zhang Z Lv C Zheng X Ma 2008 Genetic analysis of tumor necrosis factor-alpha (TNF-alpha) G-308A and saitohin Q7R polymorphisms with Alzheimer's disease J Neurol Sci 270 148 151 10.1016/j.jns.2008.02.021 18396294
    • (2008) J Neurol Sci , vol.270 , pp. 148-151
    • Wang, B.1    Zhou, S.2    Yang, Z.3    Xie, Y.C.4    Wang, J.5    Zhang, P.6    Lv, Z.7    Zheng, C.8    Ma, X.9
  • 52
    • 58149092121 scopus 로고    scopus 로고
    • The Q7R polymorphism in the saitohin gene is rare in a southern Chinese population
    • 10.1007/s10072-008-1014-2 18850062
    • K Lin M Tang Y Guo H Han Y Lin C Ma 2008 The Q7R polymorphism in the saitohin gene is rare in a southern Chinese population Neurol Sci 29 431 434 10.1007/s10072-008-1014-2 18850062
    • (2008) Neurol Sci , vol.29 , pp. 431-434
    • Lin, K.1    Tang, M.2    Guo, Y.3    Han, H.4    Lin, Y.5    Ma, C.6
  • 53
  • 54
    • 0345863891 scopus 로고    scopus 로고
    • Sequence analysis of tau 3′untranslated region and saitohin gene in sporadic progressive supranuclear palsy
    • 14707330
    • M Ezquerra J Campdelacreu E Munoz R Oliva E Tolosa 2004 Sequence analysis of tau 3′untranslated region and saitohin gene in sporadic progressive supranuclear palsy J Neurol Neurosurg Psychiatry 75 155 157 14707330
    • (2004) J Neurol Neurosurg Psychiatry , vol.75 , pp. 155-157
    • Ezquerra, M.1    Campdelacreu, J.2    Munoz, E.3    Oliva, R.4    Tolosa, E.5
  • 56
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • 6610841
    • G McKhann D Drachman M Folstein R Katzman D Price EM Stadlan 1984 Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease Neurology 34 939 944 6610841
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 60
    • 34547145165 scopus 로고    scopus 로고
    • G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences
    • 17695343
    • F Faul E Erdfelder AG Lang A Buchner 2007 G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences Behav Res Methods 39 175 191 17695343
    • (2007) Behav Res Methods , vol.39 , pp. 175-191
    • Faul, F.1    Erdfelder, E.2    Lang, A.G.3    Buchner, A.4
  • 61
    • 0006463359 scopus 로고    scopus 로고
    • Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
    • DOI 10.1126/science.274.5292.1527
    • KP Lesch D Bengel A Heils SZ Sabol BD Greenberg S Petri J Benjamin CR Muller DH Hamer DL Murphy 1996 Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region Science 274 1527 1531 10.1126/science.274.5292.1527 8929413 (Pubitemid 26403928)
    • (1996) Science , vol.274 , Issue.5292 , pp. 1527-1531
    • Lesch, K.-P.1    Bengel, D.2    Heils, A.3    Sabol, S.Z.4    Greenberg, B.D.5    Petri, S.6    Benjamin, J.7    Muller, C.R.8    Hamer, D.H.9    Murphy, D.L.10
  • 62
    • 56749095159 scopus 로고    scopus 로고
    • New approaches to the treatment of frontotemporal lobar degeneration
    • 10.1097/WCO.0b013e328318444d 18989117
    • KA Vossel BL Miller 2008 New approaches to the treatment of frontotemporal lobar degeneration Curr Opin Neurol 21 708 716 10.1097/WCO.0b013e328318444d 18989117
    • (2008) Curr Opin Neurol , vol.21 , pp. 708-716
    • Vossel, K.A.1    Miller, B.L.2
  • 63
    • 0002792366 scopus 로고
    • Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: Identification as the microtubule-associated protein tau
    • 10.1073/pnas.85.11.4051 3131773
    • M Goedert CM Wischik RA Crowther JE Walker A Klug 1988 Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau Proc Natl Acad Sci USA 85 4051 4055 10.1073/pnas.85.11.4051 3131773
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 4051-4055
    • Goedert, M.1    Wischik, C.M.2    Crowther, R.A.3    Walker, J.E.4    Klug, A.5
  • 64
    • 0026488111 scopus 로고
    • Structure and novel exons of the human tau gene
    • 10.1021/bi00158a027 1420178
    • A Andreadis WM Brown KS Kosik 1992 Structure and novel exons of the human tau gene Biochemistry 31 10626 10633 10.1021/bi00158a027 1420178
    • (1992) Biochemistry , vol.31 , pp. 10626-10633
    • Andreadis, A.1    Brown, W.M.2    Kosik, K.S.3
  • 65
    • 0024745894 scopus 로고
    • Multiple isoforms of human microtubule-associated protein tau: Sequences and localization in neurofibrillary tangles of Alzheimer's disease
    • 10.1016/0896-6273(89)90210-9 2484340
    • M Goedert MG Spillantini R Jakes D Rutherford RA Crowther 1989 Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease Neuron 3 519 526 10.1016/0896-6273(89)90210-9 2484340
    • (1989) Neuron , vol.3 , pp. 519-526
    • Goedert, M.1    Spillantini, M.G.2    Jakes, R.3    Rutherford, D.4    Crowther, R.A.5
  • 66
    • 0024387161 scopus 로고
    • Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: Differential expression of tau protein mRNAs in human brain
    • 2498079
    • M Goedert MG Spillantini MC Potier J Ulrich RA Crowther 1989 Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain EMBO J 8 393 399 2498079
    • (1989) EMBO J , vol.8 , pp. 393-399
    • Goedert, M.1    Spillantini, M.G.2    Potier, M.C.3    Ulrich, J.4    Crowther, R.A.5
  • 72
    • 0034789533 scopus 로고    scopus 로고
    • Relationship of the extended tau haplotype to tau biochemistry and neuropathology in progressive supranuclear palsy
    • DOI 10.1002/ana.1159
    • WK Liu TV Le J Adamson M Baker N Cookson J Hardy M Hutton SH Yen DW Dickson 2001 Relationship of the extended tau haplotype to tau biochemistry and neuropathology in progressive supranuclear palsy Ann Neurol 50 494 502 10.1002/ana.1159 11601500 (Pubitemid 32938894)
    • (2001) Annals of Neurology , vol.50 , Issue.4 , pp. 494-502
    • Liu, W.-K.1    Le, T.V.2    Adamson, J.3    Baker, M.4    Cookson, N.5    Hardy, J.6    Hutton, M.7    Yen, S.-H.8    Dickson, D.W.9
  • 77
    • 17144379764 scopus 로고    scopus 로고
    • The tau gene haplotype H1 confers a susceptibility to Parkinson's disease
    • DOI 10.1159/000082956
    • J Zhang Y Song H Chen D Fan 2005 The tau gene haplotype h1 confers a susceptibility to Parkinson's disease Eur Neurol 53 15 21 10.1159/000082956 15627775 (Pubitemid 40522826)
    • (2005) European Neurology , vol.53 , Issue.1 , pp. 15-21
    • Zhang, J.1    Song, Y.2    Chen, H.3    Fan, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.