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Volumn 46, Issue 1, 2011, Pages 65-70
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Discovery of a novel nitroimidazolyl-oxazolidinone hybrid with potent anti Gram-positive activity: Synthesis and antibacterial evaluation
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b
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b
d
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f
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a,d
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Author keywords
Cytotoxicity; In vitro antibacterial activity; Nitroimidazole; Oxazolidinone
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Indexed keywords
ANTIBIOTIC AGENT;
CIPROFLOXACIN;
LINEZOLID;
N [[3 [3 FLUORO 4 (N 1 PIPERAZINYL)PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE;
N [[3 [3 FLUORO 4 [4 [5 (1 METHYL 5 NITRO 1H IMIDAZOL 2 YL) 1,3,4 THIADIAZOL 2 YL]PIPERAZIN 1 YL]PHENYL] 2 OXOOXAZOLIDIN 5 YL]METHYL]ACETAMIDE;
N [[3 [3 FLUORO 4 [4 [5 (5 NITROFURAN 2 YL) 1,3,4 THIADIAZOL 2 YL] 1 PIPERAZINYL]PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE;
N [[3 [3 FLUORO 4 [4 [5 (5 NITROTHIOPHENE 2 YL) 1,3,4 THIADIAZOL 2 YL] 1 PIPERAZINYL]PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE;
NITROFURAN DERIVATIVE;
UNCLASSIFIED DRUG;
ANIMAL CELL;
ANTIMICROBIAL ACTIVITY;
ARTICLE;
BACILLUS SUBTILIS;
CORYNEBACTERIUM GLUTAMICUM;
CYTOTOXICITY;
DRUG SYNTHESIS;
ESCHERICHIA COLI;
FIBROBLAST;
GRAM NEGATIVE BACTERIUM;
GRAM POSITIVE BACTERIUM;
KLEBSIELLA PNEUMONIAE;
MICROCOCCUS LUTEUS;
MINIMUM INHIBITORY CONCENTRATION;
MOUSE;
NONHUMAN;
PSEUDOMONAS AERUGINOSA;
STAPHYLOCOCCUS AUREUS;
STAPHYLOCOCCUS EPIDERMIDIS;
STAPHYLOCOCCUS LENTUS;
STAPHYLOCOCCUS SAPROPHYTICUS;
STAPHYLOCOCCUS WARNERI;
STAPHYLOCOCCUS XYLOSUS;
ANIMALS;
ANTI-BACTERIAL AGENTS;
DRUG DISCOVERY;
GRAM-POSITIVE BACTERIA;
MICE;
NIH 3T3 CELLS;
NITROIMIDAZOLES;
OXAZOLIDINONES;
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EID: 78650514256
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2010.10.015 Document Type: Article |
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Times cited : (62)
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References (27)
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