Synthesis and antibacterial activity of isothiazolyl oxazolidinones and analogous 3(2H)-isothiazolones

European Journal of Medicinal Chemistry

Volumn 45, Issue 1, 2010, Pages 19-24

  Adibpour, Neda ^a   Khalaj, Ali ^b   Rajabalian, Saeed ^c  

^a AHVAZ JUNDISHAPUR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c KERMAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

2 Oxazolidinone; 3(2H) isothiazolone; Antibacterial activity

Indexed keywords

2 (3 FLUORO 4 MORPHOLINOPHENYL)ISOTHIAZOL 3(2H) ONE; 2 (3 FLUOROPHENYL)ISOTHIAZOL 3(2H) ONE; 2 (4 FLUOROPHENYL)ISOTHIAZOL 3(2H) ONE; 3 (3 CHLOROPHENYL) 5 [(3 OXOISOTHIAZOL 2(3H) YL)METHYL]OXAZOLIDIN 2 ONE; 3 (3 FLUORO 4 MORPHOLINOPHENYL) 5 [(3 OXOISOTHIAZOL 2(3H) YL)METHYL]OXAZOLIDIN 2 ONE; 3 (3 FLUOROPHENYL) 5 [(3 OXOISOTHIAZOL 2(3H) YL)METHYL]OXAZOLIDIN 2 ONE; 3 (4 ACETYLPHENYL) 5 [(3 OXOISOTHIAZOL 2(3H) YL)METHYL]OXAZOLIDIN 2 ONE; 3 (4 CHLOROPHENYL) 5 [(3 OXOISOTHIAZOL 2(3H) YL)METHYL]OXAZOLIDIN 2 ONE; 3 (4 FLUOROPHENYL) 5 [(3 OXOISOTHIAZOL 2(3H) YL)METHYL]OXAZOLIDIN 2 ONE; 3 (4 METHOXYPHENYL) 5 [(3 OXOISOTHIAZOL 2(3H) YL)METHYL]OXAZOLIDIN 2 ONE; 3 BENZYL 5 [(3 OXOISOTHIAZOL 2(3H) YL)METHYL]OXAZOLIDIN 2 ONE; 5 [(3 OXOISOTHIAZOL 2(3H) YL)METHYL] 3 (4 TOLYLOXAZOLIDIN) 2 ONE; 5 [(3 OXOISOTHIAZOL 2(3H) YL)METHYL] 3 [4 (TRIFLUOROMETHYL)PHENYL]OXAZOLIDIN 2 ONE; 5 [(3 OXOISOTHIAZOL 2(3H) YL)METHYL] 3 PHENYLOXAZOLIDIN 2 ONE; 5 CHLORO 2 (3 CHLOROPHENYL)ISOTHIAZOL 3(2H) ONE; 5 CHLORO 2 (3 FLUORO 4 MORPHOLINOPHENYL)ISOTHIAZOL 3(2H) ONE; 5 CHLORO 2 (3 FLUOROPHENYL)ISOTHIAZOL 3(2H) ONE; 5 CHLORO 2 (4 FLUOROPHENYL)ISOTHIAZOL 3(2H) ONE; ANTIINFECTIVE AGENT; CIPROFLOXACIN; ISOTHIAZOLE DERIVATIVE; LINEZOLID; OXAZOLIDINONE DERIVATIVE; UNCLASSIFIED DRUG; VANCOMYCIN;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; CELL STRAIN 3T3; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM; STAPHYLOCOCCUS EPIDERMIDIS;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIA; MICE; MICROBIAL SENSITIVITY TESTS; NIH 3T3 CELLS; OXAZOLIDINONES; THIAZOLES;

EID: 72049124277     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.09.019     Document Type: Article

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