Facile synthesis and biological evaluation of 3,3-diphenylpropanoyl piperazines as T-type calcium channel blockers

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 1, 2011, Pages 215-219

  Choi, Yeon Hee ^a,b   Baek, Du Jong ^b   Seo, Seon Hee ^a   Lee, Jae Kyun ^a   Pae, Ae Nim ^a,c   Cho, Yong Seo ^a,c   Min, Sun Joon ^a,c  

^a Korea Institute of Science and Technology   (South Korea)

^b Sangmyung University   (South Korea)

^c University of Science and Technology (UST)   (South Korea)

Author keywords

3,3 Diphenylpropanoyl piperazine; HTS assays; Meldrum's acid; T Type calcium channel blockers

Indexed keywords

3,3 DIPHENYLPROPANOYLPIPERAZINE DERIVATIVE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL T TYPE; UNCLASSIFIED DRUG;

ARTICLE; CROSS COUPLING REACTION; DRUG SCREENING; DRUG SYNTHESIS;

BENZHYDRYL COMPOUNDS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, T-TYPE; ETHER-A-GO-GO POTASSIUM CHANNELS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; PIPERAZINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78650511276     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.11.033     Document Type: Article

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