Biamphiphilic triblock copolymer micelles as a multifunctional platform for anticancer drug delivery

Journal of Biomedical Materials Research - Part A

Volumn 96 A, Issue 2, 2011, Pages 330-340

  Zhu, Wen ^a   Li, Yanli ^b   Liu, Lixin ^b   Zhang, Wenlong ^a   Chen, Yongming ^a   Xi, Fu ^a  

^a INSTITUTE OF CHEMISTRY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

block copolymers; cisplatin; doxorubicin; drug delivery systems; nanoparticles

Indexed keywords

ANTI-CANCER DRUG DELIVERY; ANTICANCER DRUG; AQUEOUS SOLUTIONS; BLADDER CARCINOMA; CAPROLACTONE; CIS-PLATIN; CONTROLLED POLYMERIZATION; COVALENT INTERACTIONS; CRITICAL MICELLIZATION CONCENTRATION; DIFFERENT MECHANISMS; DOXORUBICIN; DRUG DELIVERY SYSTEMS; DRUG LOADING; EJ CELLS; HYDRODYNAMIC RADIUS; HYDROPHOBIC DRUG; MICELLAR CORE; MULTI-FUNCTIONAL NANOCARRIERS; POLY(ACRYLIC ACID ); RELEASE PROFILES; SELF-ASSEMBLED; TRIBLOCK COPOLYMERS;

BIOCOMPATIBILITY; BIODEGRADATION; BLOCK COPOLYMERS; CARBOXYLIC ACIDS; COPOLYMERIZATION; DRUG DELIVERY; DYNAMIC LIGHT SCATTERING; ETHYLENE; ETHYLENE GLYCOL; HYDROPHOBICITY; MICELLES; NANOPARTICLES; ORGANIC ACIDS; PLASTIC PRODUCTS; PLATINUM COMPOUNDS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES;

DRUG INTERACTIONS;

CISPLATIN; COPOLYMER; DOXORUBICIN; NANOCARRIER; POLY(ETHYLENE GLYCOL) B POLY(EPSILON CAPROLACTONE) B POLY(ACRYLIC ACID) COPOLYMER; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; BIOCOMPATIBILITY; BIODEGRADABILITY; BLADDER CARCINOMA; CYTOTOXICITY; DRUG DELIVERY SYSTEM; HUMAN; HUMAN CELL; LIGHT SCATTERING; MICELLE; POLYMERIZATION;

ACRYLIC RESINS; ANTINEOPLASTIC AGENTS; CELL DEATH; CELL LINE, TUMOR; CHROMATOGRAPHY, GEL; CISPLATIN; DOXORUBICIN; DRUG DELIVERY SYSTEMS; FLUORESCENCE; HUMANS; INHIBITORY CONCENTRATION 50; LIGHT; MAGNETIC RESONANCE SPECTROSCOPY; MICELLES; NANOPARTICLES; POLYESTERS; POLYMERS; PYRENES; SCATTERING, RADIATION; SURFACE-ACTIVE AGENTS; TIME FACTORS;

EID: 78650484464     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.32985     Document Type: Article

References (58)

1. Adams ML, Lavasanifar A, Kwon GS,. Amphiphilic block copolymers for drug delivery. J Pharm Sci 2003; 92: 1343-1355. (Pubitemid 36792748)
2. Jones MC, Leroux JC,. Polymeric micelles-A new generation of colloidal drug carriers. Eur J Pharm Biopharm 1999; 48: 101-111.
3. Rosler A, Vandermeulen GWM, Klok HA,. Advanced drug delivery devices via self-assembly of amphiphilic block copolymers. Adv Drug Deliv Rev 2001; 53: 95-108. (Pubitemid 33152835)
4. Mikhail AS, Allen C,. Block copolymer micelles for delivery of cancer therapy: Transport at the whole body, tissue and cellular levels. J Control Release 2009; 138: 214-223.
5. Nishiyama N, Kataoka K,. Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery. Pharmacol Ther 2006; 112: 630-648. (Pubitemid 44592613)
6. Kwon GS, Forrest ML,. Amphiphilic block copolymer micelles for nanoscale drug delivery. Drug Develop Res 2006; 67: 15-22. (Pubitemid 43765046)
7. Park JH, Lee S, Kim JH, Park K, Kim K, Kwon IC,. Polymeric nanomedicine for cancer therapy. Prog Polym Sci 2008; 33: 113-137. (Pubitemid 350278530)
8. Torchilin VP,. Structure and design of polymeric surfactant-based drug delivery systems. J Control Release 2001; 73: 137-172. (Pubitemid 32544594)
9. Maeda H, Greish K, Fang J,. The EPR effect and polymeric drugs: A paradigm shift for cancer chemotherapy in the 21st century. Adv Polym Sci 2006; 193: 103-121.
10. Duncan R,. The dawning era of polymer therapeutics. Nat Rev Drug Discov 2003; 2: 347-360. (Pubitemid 37361705)
11. Torchilin VP,. Micellar nanocarriers: Pharmaceutical perspectives. Pharm Res 2007; 24: 1-16.
12. Zhang Q, Remsen EE, Wooley KL,. Shell cross-linked nanoparticles containing hydrolytically degradable, crystalline core domains. J Am Chem Soc 2000; 122: 3642-3651. (Pubitemid 30233434)
13. Narrainen AP, Pascual S, Haddleton DM,. Amphiphilic diblock, triblock, and star block copolymers by living radical polymerization: Synthesis and aggregation behavior. J Polym Sci Part A: Polym Chem 2002; 40: 439-450. (Pubitemid 34125980)
14. Stenzel MH, Barner-Kowollik C, Davis TP, Dalton HM,. Amphiphilic block copolymers based on poly (2-acryloyloxyethyl phosphorylcholine) prepared via RAFT polymerisation as biocompatible nanocontainers. Macromol Biosci 2004; 4: 445-453. (Pubitemid 39257169)
15. ten Cate MGJ, Rettig H, Bernhardt K, Borner HG,. Sequence-defined polypeptide-polymer conjugates utilizing reversible addition fragmentation transfer radical polymerization. Macromolecules 2005; 38: 10643-10649. (Pubitemid 43099312)
16. Kim JH, Emoto K, Iijima M, Nagasaki Y, Aoyagi T, Okano T, Sakurai Y, Kataoka K,. Core-stabilized polymeric micelle as potential drug carrier: Increased solubilization of taxol. Polym Advan Technol 1999; 10: 647-654. (Pubitemid 30509479)
17. Tian HY, Deng C, Lin H, Sun JR, Deng MX, Chen XS, Jing XB,. Biodegradable cationic PEG-PEI-PBLG hyperbranched block copolymer: Synthesis and micelle characterization. Biomaterials 2005; 26: 4209-4217. (Pubitemid 40430847)
18. Xu FJ, Neoh KG, Kang ET,. Bioactive surfaces and biomaterials via atom transfer radical polymerization. Prog Polym Sci 2009; 34: 719-761.
19. Kwon GS, Kataoka K,. Block-copolymer micelles as long-circulating drug vehicles. Adv Drug Deliv Rev 1995; 16: 295-309.
20. Kwon GS,. Polymeric micelles for delivery of poorly water-soluble compounds. Crit Rev Ther Drug Carrier Syst 2003; 20: 357-403.
21. Bae Y, Fukushima S, Harada A, Kataoka K,. Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: Polymeric micelles that are responsive to intracellular pH change. Angew Chem Int Edit 2003; 42: 4640-4643. (Pubitemid 37271305)
22. Shuai XT, Ai H, Nasongkla N, Kim S, Gao JM,. Micellar carriers based on block copolymers of poly(e-caprolactone) and poly(ethylene glycol) for doxorubicin delivery. J Control Release 2004; 98: 415-426. (Pubitemid 39093952)
23. Xu PS, Van Kirk EA, Murdoch WJ, Zhan YH, Isaak DD, Radosz M, Shen YQ,. Anticancer efficacies of cisplatin-releasing pH-responsive nanoparticles. Biomacromolecules 2006; 7: 829-835.
24. Shuai XT, Merdan T, Schaper AK, Xi F, Kissel T,. Core-cross-linked polymeric micelles as paclitaxel carriers. Bioconjug Chem 2004; 15: 441-448. (Pubitemid 38657848)
25. Soo PL, Lovric J, Davidson P, Maysinger D, Eisenberg A,. Polycaprolactone-block-poly(ethylene oxide) micelles: A nanodelivery system for 17 beta-estradiol. Mol Pharm 2005; 2: 519-527.
26. Nishiyama N, Kato Y, Sugiyama Y, Kataoka K,. Cisplatin-loaded polymer-metal complex micelle with time-modulated decaying property as a novel drug delivery system. Pharm Res 2001; 18: 1035-1041. (Pubitemid 32799952)
27. Nishiyama N, Okazaki S, Cabral H, Miyamoto M, Kato Y, Sugiyama Y, Nishio K, Matsumura Y, Kataoka K,. Novel cisplatin-incorporated polymeric micelles can eradicate solid tumors in mice. Cancer Res 2003; 63: 8977-8983. (Pubitemid 38064079)
28. Chiu GNC, Wong MY, Ling LU, Shaikh IM, Tan KB, Chaudhury A, Tan BJ,. Lipid-based nanoparticulate systems for the delivery of anti-cancer drug cocktails: Implications on pharmacokinetics and drug toxicities. Curr Drug Metab 2009; 10: 861-874.
29. Harasym TO, Tardi PG, Harasym NL, Harvie P, Johnstone SA, Mayer LD,. Increased preclinical efficacy of irinotecan and floxuridine coencapsulated inside liposomes is associated with tumor delivery of synergistic drug ratios. Oncol Res 2007; 16: 361-374. (Pubitemid 47413252)
30. Flavell DJ, Noss A, Pulford KAF, Ling N, Flavell SU,. Systemic therapy with 3BIT, a triple combination cocktail of anti-CD19, -CD22, and -CD38-saporin immunotoxins, is curative of human B-cell lymphoma in severe combined immunodeficient mice. Cancer Res 1997; 57: 4824-4829. (Pubitemid 27468990)
31. Frassineti GL, Zoli W, Silvestro L, Serra P, Milandri C, Tienghi A, Gianni L, Gentile A, Salzano E, Amadori D,. Paclitaxel plus doxorubicin in breast cancer: An Italian experience. Semin Oncol 1997; 24: 19-25. (Pubitemid 27505998)
32. Ahmed F, Pakunlu RI, Srinivas G, Brannan A, Bates F, Klein ML, Minko T, Discher DE,. Shrinkage of a rapidly growing tumor by drug-loaded polymersomes: pH-triggered release through copolymer degradation. Mol Pharm 2006; 3: 340-350. (Pubitemid 44021440)
33. Wei L, Cai CH, Lin JP, Chen T,. Dual-drug delivery system based on hydrogel/micelle composites. Biomaterials 2009; 30: 2606-2613.
34. Lee JS, Bae JW, Joung YK, Lee SJ, Han DK, Park KD,. Controlled dual release of basic fibroblast growth factor and indomethacin from heparin-conjugated polymeric micelle. Int J Pharm 2008; 346: 57-63. (Pubitemid 350110508)
35. Qiu LY, Bae YH,. Self-assembled polyethylenimine-graft-poly (epsilon-caprolactone) micelles as potential dual carriers of genes and anticancer drugs. Biomaterials 2007; 28: 4132-4142.
36. Nasongkla N, Bey E, Ren JM, Ai H, Khemtong C, Guthi JS, Chin SF, Sherry AD, Boothman DA, Gao JM,. Multifunctional polymeric micelles as cancer-targeted. MRI-ultrasensitive drug delivery systems. Nano Lett 2006; 6: 2427-2430. (Pubitemid 46076928)
37. Blanco E, Kessinger CW, Sumer BD, Gao J,. Multifunctional micellar nanomedicine for cancer therapy. Exp Biol Med 2009; 234: 123-131.
38. Hong GB, Yuan RX, Liang BL, Shen J, Yang XQ, Shuai XT,. Folate functionalized polymeric micelle as hepatic carcinoma-targeted. MRI-ultrasensitive delivery system of antitumor drugs. Biomed Microdevices 2008; 10: 693-700.
39. Rapoport N, Gao ZG, Kennedy A,. Multifunctional nanoparticles for combining ultrasonic tumor imaging and targeted chemotherapy. J Natl Cancer Inst 2007; 99: 1095-1106. (Pubitemid 47241394)
40. Bae Y, Jang WD, Nishiyama N, Fukushima S, Kataoka K,. Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery. Mol Biosyst 2005; 1: 242-250. (Pubitemid 41442434)
41. Huang CK, Lo CL, Chen HH, Hsiue GH,. Multifunctional micelles for cancer cell targeting, distribution imaging, and anticancer drug delivery. Adv Funct Mater 2007; 17: 2291-2297.
42. Liu FT, Eisenberg A,. Preparation and pH triggered inversion of vesicles from poly(acrylic acid)-block-polystyrene-block-poly(4-vinyl pyridine). J Am Chem Soc 2003; 125: 15059-15064. (Pubitemid 37509669)
43. Azzam T, Bronstein L, Eisenberg A,. Water-soluble surface-anchored gold and palladium nanoparticles stabilized by exchange of low molecular weight ligands with biamphiphilic triblock copolymers. Langmuir 2008; 24: 6521-6529.
44. Wittemann A, Azzam T, Eisenberg A,. Biocompatible polymer vesicles from biamphiphilic triblock copolymers and their interaction with bovine serum albumin. Langmuir 2007; 23: 2224-2230. (Pubitemid 46406186)
45. Pratt RC, Lohmeijer BGG, Long DA, Waymouth RM, Hedrick JL,. Triazabicyclodecene: A simple bifunctional organocatalyst for acyl transfer and ring-opening polymerization of cyclic esters. J Am Chem Soc 2006; 128: 4556-4557.
46. Ye HF, Jin L, Hu RZ, Yi ZF, Li J, Wu YL, Xuguang XG, Wu ZR,. Poly(gamma, L -glutamic acid)-cisplatin conjugate effectively inhibits human breast tumor xenografted in nude mice. Biomaterials 2006; 27: 5958-5965. (Pubitemid 44332519)
47. Nishiyama N, Kataoka K,. Preparation and characterization of size-controlled polymeric micelle containing cis-dichlorodiammineplatinum(II) in the core. J Control Release 2001; 74: 83-94. (Pubitemid 32727612)
48. Schechter B, Rosing MA, Wilchek M, Arnon R,. Blood-levels and serum-protein binding of cis-platinum(II) complexed to carboxymethyl-dextran. Cancer Chemother Pharmacol 1989; 24: 161-166. (Pubitemid 19163399)
49. Colombani O, Ruppel M, Schubert F, Zettl H, Pergushov DV, Muller AHE,. Synthesis of poly(n-butyl acrylate)-block-poly(acrylic acid) diblock copolymers by ATRP and their micellization in water. Macromolecules 2007; 40: 4338-4350. (Pubitemid 47012591)
50. Seow WY, Xue JM, Yang YY,. Targeted and intracellular delivery of paclitaxel using multi-functional polymeric micelles. Biomaterials 2007; 28: 1730-1740. (Pubitemid 46098966)
51. Allen C, Yu YS, Maysinger D, Eisenberg A,. Polycaprolactone-b- poly(ethylene oxide) block copolymer micelles as a novel drug delivery vehicle for neurotrophic agents FK506 and L-685,818. Bioconjug Chem 1998; 9: 564-572. (Pubitemid 28437000)
52. Giacomelli C, Borsali R,. Morphology of poly(ethylene oxide)-block-polycaprolatone block copolymer micelles controlled via the preparation method. Macromol Symp 2006; 245: 147-153. (Pubitemid 46396310)
53. Gan ZH, Jim TF, Li M, Yuer Z, Wang SG, Wu C,. Enzymatic biodegradation of poly(ethylene oxide-b-epsilon-caprolactone) diblock copolymer and its potential biomedical applications. Macromolecules 1999; 32: 590-594.
54. Zhang GD, Zhang R, Wen XX, Li L, Li C,. Micelles based on biodegradable poly(L -glutamic acid)-b-polylactide with paramagnetic gd ions chelated to the shell layer as a potential nanoscale IVIRI-visible delivery system. Biomacromolecules 2008; 9: 36-42. (Pubitemid 351201579)
55. Nishiyama N, Yokoyama M, Aoyagi T, Okano T, Sakurai Y, Kataoka K,. Preparation and characterization of self-assembled polymer-metal complex micelle from cis-dichlorodiammineplatinum(II) and poly(ethylene glycol)-poly(alpha, beta-aspartic acid) block copolymer in an aqueous medium. Langmuir 1999; 15: 377-383.
56. Lackey CA, Press OW, Hoffman AS, Stayton PS,. A biomimetic pH-responsive polymer directs endosomal release and intracellular delivery of an endocytosed antibody complex. Bioconjug Chem 2002; 13: 996-1001.
57. Lo CL, Huang CK, Lin KM, Hsiue GH,. Mixed micelles formed from graft and diblock copolymers for application in intracellular drug delivery. Biomaterials 2007; 28: 1225-1235.
58. Wang F, Wang YC, Yan LF, Wang J,. Biodegradable vesicular nanocarriers based on poly(epsilon-caprolactone)-block-poly(ethyl ethylene phosphate) for drug delivery. Polymer 2009; 50: 5048-5054.