Blood concentrations are better predictors of chioroquine poisoning severity than plasma concentrations: A prospective study with modeling of the concentration/effect relationships

Clinical Toxicology

Volumn 48, Issue 9, 2010, Pages 904-915

  Mégarbane, Bruno ^a,b   Bloch, Vanessa ^a,b   Hirt, Deborah ^b   Debray, Marcel ^b   Résiére, Dabor ^a   Deye, Nicolas ^a,b   Baud, Frédéric J ^a,b  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b INSERM   (France)

Author keywords

Acute poisoning; Cardiovascular failure; Chloroquine; Concentrationeffect relationships; Epinephrine; Intensive care unit

Indexed keywords

ADRENALIN; BICARBONATE; CHLOROQUINE; DEETHYLCHLOROQUINE; LACTIC ACID;

ADULT; ARTICLE; ARTIFICIAL VENTILATION; BLOOD; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG INTOXICATION; FEMALE; HEART ARREST; HUMAN; MALE; MODEL; PLASMA; PROGNOSIS;

ACUTE DISEASE; ADULT; ANTIMALARIALS; CHLOROQUINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MALE; MODELS, BIOLOGICAL; PROGNOSIS; PROSPECTIVE STUDIES;

EID: 78650481196     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.3109/15563650.2010.518969     Document Type: Article

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