Pharmacokinetic-pharmacodynamic relationships. How are they useful in human toxicology?

Toxicology Letters

Volumn 102-103, Issue , 1998, Pages 643-648

  Baud, Frédéric J ^a  

^a HÔPITAL LARIBOISIÈRE   (France)

Author keywords

Antidote; Diagnosis; Intoxication; Pharmacodynamic; Pharmacokinetic; Prognosis

Indexed keywords

CONFERENCE PAPER; DOSE TIME EFFECT RELATION; DRUG BLOOD LEVEL; HUMAN; PRIORITY JOURNAL; PROGNOSIS; RISK ASSESSMENT; TOXICOKINETICS; TOXICOLOGY;

ACUTE DISEASE; HUMANS; PHARMACOKINETICS; POISONING; PROGNOSIS;

EID: 19244373399     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(98)00274-4     Document Type: Conference Paper

References (4)

1. Baud, F.J., Borron, S.W., Bismuth, C., 1995. Modifying toxicokinetics with antidotes. Toxicol. Lett. 82/83, 785-793.
2. Ellenhorn, M.J., Schonwald, S., Ordog, G., Wasserberger, J. (Eds.), 1997. Ellenhorn's Medical Toxicology: Diagnosis and Treatment of Human Poisoning. Williams and Wilkins, Baltimore.
3. Urtizberea, M., Rochdi, M., Baud, F.J., Scherrmann, J.M., 1990. Toxicokinetic-toxicodynamic models describing the relation of plasma and red blood cell potassium with plasma digitalis in acute human poisoning. Toxicol. In Vitro 4, 526-531.
4. Venitz, J., 1995. Pharmacokinetic-pharmacodynamic modeling of reversible drug effects. In: Derendorf, H., Hochhaus, G. (Eds.), Handbook of Pharmacokinetic/Pharmacodynamic Correlation. CRC Press, London, pp. 1-34.