Turning science into health solutions: KEMRIs challenges as Kenyas health product pathfinder

BMC International Health and Human Rights

Volumn 10, Issue SUPPL. 1, 2010, Pages

  Simiyu, Ken ^a   Masum, Hassan ^a   Chakma, Justin ^a   Singer, Peter A ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COMMERCIAL PHENOMENA; DIAGNOSTIC TEST; HEALTH CARE ORGANIZATION; HEPATITIS B; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; JAPAN; KENYA; LICENSING; LIFE CYCLE; MARKET; MEDICAL RESEARCH; MEDICAL TECHNOLOGY; PRODUCT DEVELOPMENT; RISK ASSESSMENT; SCALE UP;

EID: 78650463105     PISSN: None     EISSN: 1472698X     Source Type: Journal    
DOI: 10.1186/1472-698X-10-S1-S10     Document Type: Article

References (43)

1. The product market and the market for ideas: commercialization strategies for technology entrepreneurs. J Gans S Stern, Research Policy 2003 32 2 333 350 10.1016/S0048-7333(02)00103-8
2. National innovation system. The system approach in historical perspective. B Godin, Montreal, Canada: Project on the history and sociology of STI statistics, Working Paper No. 36 2007
3. National Systems of Biotechnology Innovation: Complex Interdependence in the Global System, S Bartholomew, Journal of International Business Studies 1997 28 2 241 266 10.1057/palgrave.jibs.8490100
4. The US National Innovation System, DC Mowery N Rosenberg, National Innovation Systems: A Comparative Analysis New York, NY: Oxford University Press, Richard Nelson, 1993
5. Assessing the impact of organizational practices on the relative productivity of university technology transfer offices: an exploratory study. D Siegel D Waldman A Link, Research Policy 2003 32 27 48 10.1016/S0048-7333(01) 00196-2
6. YM Bio Springs a Cuban Surprise, Financial Times 2002 14 June
7. The road to commercialization in Africa: lessons from developing the sickle-cell drug Niprisan. K Perampaladas H Masum A Kapoor R Shah AS Daar PA Singer, BMC International Health and Human Rights 2010 10 Suppl 1 11 10.1126/science.1115538 16020723
8. Small but tenacious: South Africas health biotech sector. S Al-Bader SE Frew I Essajee VY Liu AS Daar PA Singer, Nature Biotechnology 2009 27 5 427 445 10.1038/nbt0509-427 19430446
9. WHO | Malaria. http://www.who.int/mediacentre/factsheets/fs094/en/
10. WHO | Tuberculosis. http://www.who.int/mediacentre/factsheets/fs104/en/
11. 10/90 Report on Health Research 2003-2004. Global Forum for Health Research, 2004 Geneva
12. Freedom to Innovate: Biotechnology in Africa's Development. C Juma I Serageldin, Addis Ababa, Ethiopia; Pretoria, South Africa: Report for African Union, New Partnership for Africa's Development 2007 August
13. Innovation in Developing Countries to Meet Health Needs: experiences of China, Brazil, South Africa and India. The Centre for Management of IP in Health R&D (MIHR), MIHR 2005
14. Monitoring Financial Flows for Health Research (2009). Global Forum for Health Research, 2009 Geneva
15. Learning Through Inter-organizational Interactions: Public Research Institutes in the Nigerian (Bio)pharmaceutical System of Innovation. B Oyelaran-Oyeyinka P Gehl Sampath, European Journal of Development Research 2007 19 1 174 193 10.1080/09578810601144483 (Pubitemid 46929241)
16. National Technology Systems in Sub-Saharan Africa. S Lall C Pietrobelli, International Journal of Technology and Globalization 2005 1 3 4
17. Financing Science and Innovation in Africa: Institutional Development and Challenges. F Teng-Zeng, Science, Technology and Innovation for Public Health in Africa Johannesburg: DS Print Media, Kalua F, Awotedu A, Kamwanja L, Saka J; New Partnership for Africas Development, 2009 167 197
18. Partnerships for vaccine development: building capacity to strengthen developing country health and innovation. R Hanlin, PhD thesis University of Edinburgh, School of Social and Political Sciences 2008
19. Building the Case for Systems of Health Innovation in Africa. J Chataway K Chaturvedi R Hanlin J Mugwagwa J Smith D Wield, Science, Technology and Innovation for Public Health in Africa Johannesburg: DS Print Media, Kalua F, Awotedu A, Kamwanja L, Saka J; New Partnership for Africas Development, 2009 7 53
20. Advancing Drug Innovation for Neglected DiseasesCriteria for Lead Progression. S Nwaka B Ramirez R Brun L Maes F Douglas R Ridley, PLoS Negl Trop Dis. 2009 3 8 440 August 10.1371/journal.pntd.0000440 19707561
21. Efficacy of oral Kemron (low dose oral interferon alpha) in the management of acquired immune deficiency syndrome (AIDS). D Koech A Obel, East African Medical Journal (Special Supplement) 1990 67 7 Suppl 2 S64 SS70
22. Clinical Trials in Kenya. V Patel, http://www.webcitation.org/5kxFoxru5
23. In Kenya, a New AIDS Drug Gets Mired in Politics and Financial Disputes. Jane Perlez, The New York Times 1990 http://www.nytimes.com/1990/10/03/world/in- kenya-a-new-aids-drug-gets-mired-in-politics-and-financial-disputes.html October 3
24. NIH Plans Trials of Controversial AIDS Drug. C Anderson, Nature 1992 360 6399 8 1436079
25. Kemron trial stopped. L Highleyman, BETA (bulletin of experimental treatments for AIDS) 1997 5 1997 Sep
26. Traitement des lesions condylomateuses genitales par linterferon alpha sublingual. JM Dangou AA Kasse MT Dieng M Dembele, Médecine d'Afrique Noire 2000 47 5 259 263
27. Combination of bleach and fluorescent microscopy: a milestone in the diagnosis of smear negative tuberculosis. S Matu WA Githui LN Muthami J Makumi J Ngeranwa N Tunge E Juma F Karimi, East Afr Med J. 2007 84 10 453 4 Oct 18232264
28. From the laboratory to a patent to a product: a success story from KEMRI. S Matu, Second Meeting of the African Network for Drugs and Diagnostics Innovation (ANDI): Creating a sustainable platform for R&D innovation in Africa 4-7 October 2009 2009
29. Deoxyribonucleic acid polymerase from the extreme thermophile Thermus aquaticus. A Chien DB Edgar JM Trela, Journal of Bacteriology 1976 127 3 1550 1557 (1976) 8432
30. KEMRI e-store. http://www.kemri.org/index.php/help-desk/products?page= shop.browse&category-id=6
31. Indigenous Knowledge (IK) and Innovation Systems for Public Health in Africa. HO Kaya, Science, Technology and Innovation for Public Health in Africa Johannesburg: DS Print Media, Kalua F, Awotedu A, Kamwanja L, Saka J; New Partnership for Africas Development, 2009 95 111
32. PEPFAR Public-Private Partnerships. 2010 http://www.pepfar.gov/ppp/index. htm Accessed July 16
33. Building the Case for Systems of Health Innovation in Africa. J Chataway K Chaturvedi R Hanlin J Mugwagwa J Smith D Wield, Science, Technology and Innovation for Public Health in Africa Johannesburg: DS Print Media, Kalua F, Awotedu A, Kamwanja L, Saka J; New Partnership for Africas Development, 2009 7 53
34. The Valley of Death as Context for Role Theory in Product Innovation. SK Markham SJ Ward L Aiman-Smith AI Kingon, J Prod Innov Manag 2010 27 402 417 10.1111/j.1540-5885.2010.00724.x
35. Indias health biotech sector at a crossroads. SE Frew R Reziae SM Sammut M Ray AS Daar PA Singer, Nature Biotechnology 2007 25 403 417 10.1038/nbt0407-403 17420744
36. Chinese health biotech and the billion-patient market. SE Frew SM Sammut AF Shore JK Ramjist S Al-Bader R Rezaie AS Daar PA Singer, Nature Biotechnology 2008 26 1 37 53 10.1038/nbt0108-37 18183014
37. Bridgeworks Africa case study. McLaughlin-Rotman Centre for Global Health, 2009 Toronto, Canada
38. Open Innovation: Researching a New Paradigm. H Chesbrough W Vanhaverbeke J West, Oxford: Oxford University Press 2006
39. A Tough Transition. PA Singer K Berndtson C Shawn Tracy ERM Cohen H Masum AS Daar, Nature 2007 449 7159 160 163 (2007) 10.1038/449160a 17851510
40. A resource-based view of product development. G Verona, Academy of Management Review 1999 24 1 132 142 (1999) 10.2307/259041
41. Flying Geese in Asia: The Impacts of Japanese MNCs as a Source of Industrial Learning. R Hayter D Edgington, Tijdschrift voor Ekonomische en Sociale Geografie 2004 95 3 26 10.1111/j.0040-747X.2004.00290.x
42. A resource-based view of product development. G Verona, Academy of Management Review 1999 24 1 132 142 10.2307/259041
43. Open Innovation: Researching a New Paradigm. H Chesbrough W Vanhaverbeke J West, Oxford: Oxford University Press 2006