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Volumn 56, Issue 6, 2010, Pages 1124-1130

Adipocyte heme oxygenase-1 induction attenuates metabolic syndrome in both male and female obese mice

Author keywords

adipocyte pAMPK; female obesity; heme oxygenase inducers; inflammation

Indexed keywords

ADENYLATE KINASE; ADIPONECTIN; GLUCOSE; HEME OXYGENASE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN KINASE B; PROTOPORPHYRIN COBALT; STANNSOPORFIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 78650420124     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.110.151423     Document Type: Article
Times cited : (101)

References (38)
  • 1
    • 0026218111 scopus 로고
    • Obesity, fat distribution and cardiovascular disease
    • Larsson B. Obesity, fat distribution and cardiovascular disease. Int J Obes. 1991;15[Suppl 2]:53-57.
    • (1991) Int J Obes , vol.15 , Issue.SUPPL. 2 , pp. 53-57
    • Larsson, B.1
  • 4
    • 41149155892 scopus 로고    scopus 로고
    • Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance
    • Li M, Kim DH, Tsenovoy PL, Peterson SJ, Rezzani R, Rodella LF, Aronow WS, Ikehara S, Abraham NG. Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance. Diabetes. 2008;57:1526-1535.
    • (2008) Diabetes , vol.57 , pp. 1526-1535
    • Li, M.1    Kim, D.H.2    Tsenovoy, P.L.3    Peterson, S.J.4    Rezzani, R.5    Rodella, L.F.6    Aronow, W.S.7    Ikehara, S.8    Abraham, N.G.9
  • 5
    • 0029444525 scopus 로고
    • Visceral fat accumulation and cardiovascular disease
    • Matsuzawa Y, Nakamura T, Shimomura I, Kotani K. Visceral fat accumulation and cardiovascular disease. Obes Res. 1995;3[Suppl 5]:645S- 647S.
    • (1995) Obes Res , vol.3 , Issue.SUPPL. 5
    • Matsuzawa, Y.1    Nakamura, T.2    Shimomura, I.3    Kotani, K.4
  • 6
    • 0023035033 scopus 로고
    • Subcutaneous and visceral fat distribution according to sex, age, and overweight, evaluated by computed tomography
    • Enzi G, Gasparo M, Biondetti PR, Fiore D, Semisa M, Zurlo F. Subcutaneous and visceral fat distribution according to sex, age, and overweight, evaluated by computed tomography. Am J Clin Nutr. 1986;44:739-746.
    • (1986) Am J Clin Nutr , vol.44 , pp. 739-746
    • Enzi, G.1    Gasparo, M.2    Biondetti, P.R.3    Fiore, D.4    Semisa, M.5    Zurlo, F.6
  • 8
    • 41149177025 scopus 로고    scopus 로고
    • Pharmacological and clinical aspects of heme oxygenase
    • Abraham NG, Kappas A. Pharmacological and clinical aspects of heme oxygenase. Pharmacol Rev. 2008;60:79-127.
    • (2008) Pharmacol Rev , vol.60 , pp. 79-127
    • Abraham, N.G.1    Kappas, A.2
  • 10
    • 54749140147 scopus 로고    scopus 로고
    • Kidney specific induction of HO-1 prevents angiotensin II hypertension
    • Vera T, Kelsen S, Stec DE. Kidney specific induction of HO-1 prevents angiotensin II hypertension. Hypertension. 2008;52:660-665.
    • (2008) Hypertension , vol.52 , pp. 660-665
    • Vera, T.1    Kelsen, S.2    Stec, D.E.3
  • 11
    • 34147153226 scopus 로고    scopus 로고
    • HO-1 induction lowers blood pressure and superoxide production in the renal medulla of angiotensin II hypertensive mice
    • Vera T, Kelsen S, Yanes LL, Reckelhoff JF, Stec DE. HO-1 induction lowers blood pressure and superoxide production in the renal medulla of angiotensin II hypertensive mice. Am J Physiol Regul Integr Comp Physiol. 2007;292:R1472- R1478.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.292
    • Vera, T.1    Kelsen, S.2    Yanes, L.L.3    Reckelhoff, J.F.4    Stec, D.E.5
  • 12
    • 44249095590 scopus 로고    scopus 로고
    • Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines, tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesen-chymal stem cells
    • Kim DH, Burgess AP, Li M, Tsenovoy PL, Addabbo F, McClung JA, Puri N, Abraham NG. Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines, tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesen-chymal stem cells. J Pharmacol Exp Ther. 2008;325:833-840.
    • (2008) J Pharmacol Exp Ther , vol.325 , pp. 833-840
    • Kim, D.H.1    Burgess, A.P.2    Li, M.3    Tsenovoy, P.L.4    Addabbo, F.5    McClung, J.A.6    Puri, N.7    Abraham, N.G.8
  • 17
    • 65249172474 scopus 로고    scopus 로고
    • Heme oxygenase-derived carbon monoxide restores adiponectin levels and vascular function in type 1 diabetes
    • Rodella LF, Peterson SJ, Drummond G, Rezzani R, Falck JR, Abraham NG. Heme oxygenase-derived carbon monoxide restores adiponectin levels and vascular function in type 1 diabetes. Drug Metab Lett. 2008;2:290-300.
    • (2008) Drug Metab Lett , vol.2 , pp. 290-300
    • Rodella, L.F.1    Peterson, S.J.2    Drummond, G.3    Rezzani, R.4    Falck, J.R.5    Abraham, N.G.6
  • 20
    • 19044393872 scopus 로고    scopus 로고
    • Adipose tissue, inflammation, and cardiovascular disease
    • Berg AH, Scherer PE. Adipose tissue, inflammation, and cardiovascular disease. Circ Res. 2005;96:939-949.
    • (2005) Circ Res , vol.96 , pp. 939-949
    • Berg, A.H.1    Scherer, P.E.2
  • 22
    • 34250172420 scopus 로고    scopus 로고
    • Low serum adiponectin is associated with high circulating oxidized low-density lipoprotein in patients with type 2 diabetes mellitus and coronary artery disease
    • Lautamaki R, Ronnemaa T, Huupponen R, Lehtimaki T, Iozzo P, Juhani Airaksinen KE, Knuuti J, Nuutila P. Low serum adiponectin is associated with high circulating oxidized low-density lipoprotein in patients with type 2 diabetes mellitus and coronary artery disease. Metabolism. 2007; 56:881-886.
    • (2007) Metabolism , vol.56 , pp. 881-886
    • Lautamaki, R.1    Ronnemaa, T.2    Huupponen, R.3    Lehtimaki, T.4    Iozzo, P.5    Juhani Airaksinen, K.E.6    Knuuti, J.7    Nuutila, P.8
  • 23
    • 64049095859 scopus 로고    scopus 로고
    • PPAR-alpha activation protects the type 2 diabetic myocardium against ischemia-reperfusion injury: Involvement of the PI3-Kinase/Akt and NO pathway
    • Bulhak AA, Jung C, Ostenson CG, Lundberg JO, Sjoquist PO, Pernow J. PPAR-alpha activation protects the type 2 diabetic myocardium against ischemia-reperfusion injury: involvement of the PI3-Kinase/Akt and NO pathway. Am J Physiol Heart Circ Physiol. 2009;296:H719-H727.
    • (2009) Am J Physiol Heart Circ Physiol , vol.296
    • Bulhak, A.A.1    Jung, C.2    Ostenson, C.G.3    Lundberg, J.O.4    Sjoquist, P.O.5    Pernow, J.6
  • 24
    • 0034651983 scopus 로고    scopus 로고
    • Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart
    • Fujio Y, Nguyen T, Wencker D, Kitsis RN, Walsh K. Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart. Circulation. 2000;101:660-667.
    • (2000) Circulation , vol.101 , pp. 660-667
    • Fujio, Y.1    Nguyen, T.2    Wencker, D.3    Kitsis, R.N.4    Walsh, K.5
  • 26
    • 37349078272 scopus 로고    scopus 로고
    • Insulin resistance and endothelial cell dysfunction: Studies in mammalian models
    • Kearney MT, Duncan ER, Kahn M, Wheatcroft SB. Insulin resistance and endothelial cell dysfunction: studies in mammalian models. Exp Physiol. 2008;93:158-163.
    • (2008) Exp Physiol , vol.93 , pp. 158-163
    • Kearney, M.T.1    Duncan, E.R.2    Kahn, M.3    Wheatcroft, S.B.4
  • 28
    • 0242690438 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) regulates the insulin-induced activation of the nitric oxide synthase in human platelets
    • Fleming I, Schulz C, Fichtlscherer B, Kemp BE, Fisslthaler B, Busse R. AMP-activated protein kinase (AMPK) regulates the insulin-induced activation of the nitric oxide synthase in human platelets. Thromb Haemost. 2003;90:863-871.
    • (2003) Thromb Haemost , vol.90 , pp. 863-871
    • Fleming, I.1    Schulz, C.2    Fichtlscherer, B.3    Kemp, B.E.4    Fisslthaler, B.5    Busse, R.6
  • 29
    • 0141925771 scopus 로고    scopus 로고
    • Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart
    • Kovacic S, Soltys CL, Barr AJ, Shiojima I, Walsh K, Dyck JR. Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart. J Biol Chem. 2003;278:39422-39427.
    • (2003) J Biol Chem , vol.278 , pp. 39422-39427
    • Kovacic, S.1    Soltys, C.L.2    Barr, A.J.3    Shiojima, I.4    Walsh, K.5    Dyck, J.R.6
  • 30
    • 28444436289 scopus 로고    scopus 로고
    • Insulin signalling downstream of protein kinase B is potentiated by 5'AMP-activated protein kinase in rat hearts in vivo
    • Longnus SL, Segalen C, Giudicelli J, Sajan MP, Farese RV, Van OE. Insulin signalling downstream of protein kinase B is potentiated by 5'AMP-activated protein kinase in rat hearts in vivo. Diabetologia. 2005; 48:2591-2601.
    • (2005) Diabetologia , vol.48 , pp. 2591-2601
    • Longnus, S.L.1    Segalen, C.2    Giudicelli, J.3    Sajan, M.P.4    Farese, R.V.5    Van, O.E.6
  • 31
    • 0344081177 scopus 로고    scopus 로고
    • Minireview: The AMP-activated protein kinase cascade: The key sensor of cellular energy status
    • Hardie DG. Minireview: The AMP-activated protein kinase cascade: the key sensor of cellular energy status. Endocrinology. 2003;144:5179-5183.
    • (2003) Endocrinology , vol.144 , pp. 5179-5183
    • Hardie, D.G.1
  • 32
    • 33847072201 scopus 로고    scopus 로고
    • AMP-activated protein kinase as a drug target
    • Hardie DG. AMP-activated protein kinase as a drug target. Annu Rev Pharmacol Toxicol. 2007;47:185-210.
    • (2007) Annu Rev Pharmacol Toxicol , vol.47 , pp. 185-210
    • Hardie, D.G.1
  • 33
    • 33744931155 scopus 로고    scopus 로고
    • Heme oxygenase-1 enhances renal mitochondrial transport carriers and cytochrome C oxidase activity in experimental diabetes
    • Di Noia MA, Van DS, Palmieri F, Yang LM, Quan S, Goodman AI, Abraham NG. Heme oxygenase-1 enhances renal mitochondrial transport carriers and cytochrome C oxidase activity in experimental diabetes. J Biol Chem. 2006;281:15687-15693.
    • (2006) J Biol Chem , vol.281 , pp. 15687-15693
    • Di Noia, M.A.1    Van, D.2    Palmieri, F.3    Yang, L.M.4    Quan, S.5    Goodman, A.I.6    Abraham, N.G.7
  • 34
    • 0346463030 scopus 로고    scopus 로고
    • Adiponectin Stimulates Angiogenesis by Promoting Cross-talk between AMP-activated Protein Kinase and Akt Signaling in Endothelial Cells
    • DOI 10.1074/jbc.M310389200
    • Ouchi N, Kobayashi H, Kihara S, Kumada M, Sato K, Inoue T, Funahashi T, Walsh K. Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells. J Biol Chem. 2004;279:1304-1309. (Pubitemid 38082655)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.2 , pp. 1304-1309
    • Ouchi, N.1    Kobayashi, H.2    Kihara, S.3    Kumada, M.4    Sato, K.5    Inoue, T.6    Funahashi, T.7    Walsh, K.8
  • 37
    • 46249108461 scopus 로고    scopus 로고
    • Regulation of ROS signal transduction by NADPH oxidase 4 localization
    • Chen K, Kirber MT, Xiao H, Yang Y, Keaney JF Jr. Regulation of ROS signal transduction by NADPH oxidase 4 localization. J Cell Biol. 2008; 181:1129-1139.
    • (2008) J Cell Biol , vol.181 , pp. 1129-1139
    • Chen, K.1    Kirber, M.T.2    Xiao, H.3    Yang, Y.4    Keaney Jr., J.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.