Total synthesis of TAK-kinase inhibitor LL-Z1640-2 via consecutive macrocyclization and transannular aromatization

Organic Letters

Volumn 12, Issue 23, 2010, Pages 5573-5575

  Miyatake Ondozabal, Hideki ^a   Barrett, Anthony G M ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 DIOXOLANE DERIVATIVE; FORMAL GLYCOL; LACTONE; LL Z1640 2; LL Z1640-2; MAP KINASE KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PROTEIN KINASE INHIBITOR;

ARTICLE; CHEMICAL STRUCTURE; CYCLIZATION; DRUG ANTAGONISM; SYNTHESIS;

CYCLIZATION; DIOXOLANES; LACTONES; MAP KINASE KINASE KINASES; MOLECULAR STRUCTURE; PROTEIN KINASE INHIBITORS;

EID: 78650410551     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol102468k     Document Type: Article

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