Neurosteroids for a successful pregnancy

Stress

Volumn 14, Issue 1, 2011, Pages 1-5

  Frye, Cheryl A ^a   Hirst, Jonathan J ^b   Brunton, Paula J ^c   Russell, John A ^c  

^a STATE UNIVERSITY OF NEW YORK   (United States)

^b UNIVERSITY OF NEWCASTLE   (Australia)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

allopregnanolone; delivery; neuroactive steroids; Parity; parturition

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; CANNABINOID; GESTAGEN; HYDROXYPROGESTERONE; NEUROSTEROID; STEROID RECEPTOR; VITAMIN D;

ADOLESCENCE; CENTRAL NERVOUS SYSTEM; CLINICAL TRIAL; COGNITION; COGNITIVE DEVELOPMENT; CYTOKINE RESPONSE; ELECTROCORTICOGRAPHY; GESTAGEN BLOOD LEVEL; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; HYPOXIA; MENTAL DISEASE; NEUROPROTECTION; NORADRENERGIC NERVE; PAIN; PATHOGENESIS; PREFRONTAL CORTEX; PREGNANCY; PREMATURE LABOR; PRIORITY JOURNAL; REVIEW; SEX DIFFERENCE; SIGNAL TRANSDUCTION; STRESS; THIRD TRIMESTER PREGNANCY;

ANIMALS; CENTRAL NERVOUS SYSTEM; FEMALE; HUMANS; NEUROTRANSMITTER AGENTS; PREGNANCY; PREGNANOLONE; PROGESTERONE;

EID: 78650401525     PISSN: 10253890     EISSN: 16078888     Source Type: Journal    
DOI: 10.3109/10253890.2010.540050     Document Type: Review

References (47)

1. Barbaccia ML, Serra M, Purdy RH, Biggio G. 2001. Stress and neuroactive steroids. Int Rev Neurobiol 46:243-272.
2. Baulieu EE. 1980. Interaction of steroid hormones with their target cells. Reprod Nutr Dev 20:419-441.
3. Baulieu EE. 1991. Neurosteroids: A new function in the brain. Biol Cell 71:3-10.
4. Belelli D, Peden DR, Rosahl TW, Wafford KA, Lambert JJ. 2005. Extrasynaptic gabaa receptors of thalamocortical neurons: A molecular target for hypnotics. J Neurosci 25: 11513-11520.
5. Brunton PJ, Russell JA. 2008. The expectant brain: Adapting for motherhood. Nat Rev Neurosci 9:11-25.
6. Brunton PJ, Russell JA. 2010. Allopregnanolone and suppressed hypothalamo pituitary-adrenal axis stress responses in late pregnancy in the rat. Stress 19:6-12.
7. Compagnone NA, Mellon SH. 2000. Neurosteroids: Biosynthesis and function of these novel neuromodulators. Front Neuroendocrinol 21:1-56.
8. Concas A, Mostallino MC, Porcu P, Follesa P, Barbaccia ML, Trabucchi M, Purdy RH, Grisenti P, Biggio G. 1998. Role of brain allopregnanolone in the plasticity of gamma-aminobutyric acid type A receptor in rat brain during pregnancy and after delivery. PNAS 95:13284-13289.
9. Doggrell SA. 2003. Recurrent hope for the treatment of preterm delivery. Expert Opin Pharmacother 4:2363-2366.
10. Dzhala VI, Talos DM, Sdrulla DA, Brumback AC, Mathews GC, Benke TA, Delpire E, Jensen FE, Staley KJ. 2005. Nkcc1 transporter facilitates seizures in the developing brain. Nat Med 11:1205-1213.
11. Freeman EW, Frye CA, Rickels K, Martin PA, Smith SS. 2002. Allopregnanolone levels and symptom improvement in severe premenstrual syndrome. J Clin Psychopharmacol 22: 516-520.
12. Furukawa A, Miyatake A, Ohnishi T, Ichikawa Y. 1998. Steroidogenic acute regulatory protein (StAR) transcripts constitutively expressed in the adult rat central nervous system: Colocalization of StAR, cytochrome P-450SCC (CYP XIA1), and 3beta-hydroxysteroid dehydrogenase in the rat brain. J Neurochem 71:2231-2238.
13. Genazzani AR, Petraglia F, Bernardi F, Casarosa E, Salvestroni C, Tonetti A, Nappi RE, Luisi S, Palumbo M, Purdy RH, Luisi M. 1998. Circulating levels of allopregnanolone in humans: Gender, age, and endocrine influences. J Clin Endocrinol Metab 83: 2099-2103.
14. Gracia CR, Freeman EW, Sammel MD, Lin H, Sheng L, Frye C. 2003. Allopregnanolone levels before and after selective serotonin reuptake inhibitor treatment of premenstrual symptoms. J Clin Psychopharmacol 29:403-405.
15. Hedegaard M, Henriksen TB, Sabroe S, Secher NJ. 1993. Psychological distress in pregnancy and preterm delivery. BMJ 307:234-239. (Pubitemid 23207901)
16. Herbison AE. 2001. Physiological roles for the neurosteroid allopregnanolone in the modulation of brain function during pregnancy and parturition. Prog Brain Res 133:39-47.
17. Holzbauer M. 1975. Physiological variations in the ovarian production of 5alpha-pregnane derivatives with sedative properties in the rat. J Steroid Biochem 6:1307-1310.
18. Kauppila A, Hartikainen-Sorri AL, Jänne O, Tuimala R, Järvinen PA. 1980. Suppression of threatened premature labor by administration of cortisol and 17 alpha-hydroxyprogesterone caproate: A comparison with ritodrine. Am J Obstet Gynecol 138:404-408.
19. Keirse MJ. 1990. Progestogen administration in pregnancy may prevent preterm delivery. Br J Obstet Gynaecol 97:149-154.
20. Luisi S, Petraglia F, Benedetto C, Nappi RE, Bernardi F, Fadalti M, Reis FM, Luisi M, Genazzani AR. 2000. Serum allopregnano-lone levels in pregnant women: Changes during pregnancy, at delivery, and in hypertensive patients. J Clin Endocrinol Metab 85:2429-2433.
21. MacDorman MF, Callaghan WM, Mathews TJ, Hoyert DL, Kochanek KD. 2007. Trends in preterm-related infant mortality by race and ethnicity, United States, 1999-2004. Int J Health Serv 37:635-641.
22. Majewska MD. 1992. Neurosteroids: Endogenous bimodal modulators of the GABAA receptor. Mechanism of action and physiological significance. Prog Neurobiol 38:379-395.
23. Melcangi RC, Panzica G. 2003. Steroids and the nervous system. Introduction. Ann N Y Acad Sci 1007:1-5.
24. Mellon SH. 1994. Neurosteroids: Biochemistry, modes of action, and clinical relevance. J Clin Endocrinol Metab 78:1003-1008.
25. Nguyen PN, Billiards SS, Walker DW, Hirst JJ. 2003. Changes in 5alpha-pregnane steroids and neurosteroidogenic enzyme expression in the perinatal sheep. Pediatr Res 53:956-964.
26. Nicol MB, Hirst JJ, Walker D, Thorburn GD. 1997. Effect of alteration of maternal plasma progesterone concentrations on fetal behavioural state during late gestation. J Endocrinol 152: 379-386.
27. Paarlberg KM, Vingerhoets AJ, Passchier J, Dekker GA, Van Geijn HP. 1995. Psychosocial factors and pregnancy outcome: A review with emphasis on methodological issues. J Psychosom Res 39:563-595.
28. Paris JJ, Frye CA. 2008. Estrous cycle, pregnancy, and parity enhance performance of rats in object recognition or object placement tasks. Reproduction 136:105-115.
29. Paris JJ, Frye CA. 2010. Juvenile offspring of rats exposed to restraint stress in late gestation have impaired cognitive performance and dysregulated progestogen formation. Stress 19:23-32.
30. Patchev VK, Hassan AH, Holsboer DF, Almeida OF. 1996. The neurosteroid tetrahydroprogesterone attenuates the endocrine response to stress and exerts glucocorticoid-like effects on vasopressin gene transcription in the rat hypothalamus. Neuropsychopharmacology 15:533-540.
31. Paul SM, Purdy RH. 1992. Neuroactive steroids. FASEB J 6: 2311-2322.
32. Pearce BD, Garvin SE, Grove J, Bonney EA, Dudley DJ, Schendel DE, Thorsen P. 2008. Serum macrophage migration inhibitory factor in the prediction of preterm delivery. Am J Obstet Gynecol 199:46e1-46e6.
33. Petrini JR, Dias T, McCormick MC, Massolo ML, Green NS, Escobar GJ. 2009. Increased risk of adverse neurological development for late preterm infants. J Pediatr 154:169-176.
34. Purdy RH, Moore PH Jr, Rao PN, Hagino N, Yamaguchi T, Schmidt P, Rubinow DR, Morrow AL, Paul SM. 1990. Radioimmunoassay of 3 alpha-hydroxy-5 alpha-pregnan-20-one in rat and human plasma. Steroids 55:290-296.
35. Rini CK, Dunkel-Schetter C, Wadhwa PD, Sandman CA. 1999. Psychological adaptation and birth outcomes: The role of personal resources, stress, and sociocultural context in pregnancy. Health Psychol 18:333-345.
36. Rivera C, Voipio J, Payne JA, Ruusuvuori E, Lahtinen H, Lamsa K, Pirvola U, Saarma M, Kaila K. 1999. The k \+ /cl- co-transporter kcc2 renders gaba hyperpolarizing during neuronal maturation. Nature 397:251-255.
37. Sanchez-Ramos L. 2005. Induction of labor. Obstet Gynecol Clin North Am 32:181-200, viii.
38. Sundström I, Bäckström T. 1998a. Patients with premenstrual syndrome have decreased saccadic eye velocity compared to control subjects. Biol Psychiatry 44:755-764.
39. Sundström I, Bäckström T. 1998b. Citalopram increases pregna-nolone sensitivity in patients with premenstrual syndrome: An open trial. Psychoneuroendocrinology 23:73-88.
40. Sundström I, Bäckström T, Wang M, Olsson T, Seippel L, Bixo M. 1999. Premenstrual syndrome, neuroactive steroids and the brain. Gynecol Endocrinol 13:206-220.
41. Vu TT, Hirst JJ, Stark M, Wright IMR, Palliser HK, Hodyl N, Clifton VL. 2009. Changes in human placental 5alpha-reductase isoenzyme expression with advancing gestation: Effects of fetal sex and glucocorticoid exposure. Reprod Fertil Dev 21: 599-607.
42. Wadhwa PD, Sandman CA, PortoM,Dunkel-SchetterC,Garite TJ. 1993. The association between prenatal stress and infant birth weight and gestational age at birth: A prospective investigation. Am J Obstet Gynecol 169:858-865.
43. Wang M, Seippel L, Purdy RH, Bãckström T. 1996. Relationship between symptom severity and steroid variation in women with premenstrual syndrome: Study on serum pregne-nolone, pregnenolone sulfate, 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one. J Clin Endocrinol Metab 81:1076-1082.
44. Williams MT, Davis HN, McCrea AE, Long SJ, Hennessy MB. 1999. Changes in the hormonal concentrations of pregnant rats and their fetuses following multiple exposures to a stressor during the third trimester. Neurotoxicol Teratol 21:403-414.
45. Xiong X, Harville EW, Mattison DR, Elkind-Hirsch K, Pridjian G, Buekens P. 2008. Exposure to Hurricane Katrina, post-traumatic stress disorder and birth outcomes. Am J Med Sci 336:111-115.
46. Yawno T, Yan EB, Walker DW, Hirst JJ. 2007. Inhibition of neurosteroid synthesis increases asphyxia-induced brain injury in the late gestation fetal sheep. Neuroscience 146:1726-1733.
47. Yawno T, Yan EB, Hirst JJ, Walker DW. 2010. Neuroactive steroids induce changes in fetal sheep behavior during normoxic and asphyxic states Stress 19:13-22.