Tomosyn inhibits synaptotagmin-1-mediated step of Ca2+-dependent neurotransmitter release through its N-terminal WD40 repeats

Journal of Biological Chemistry

Volumn 285, Issue 52, 2010, Pages 40943-40955

  Yamamoto, Yasunori ^a   Mochida, Sumiko ^b   Miyazaki, Naoyuki ^c,d   Kawai, Katsuhisa ^a   Fujikura, Kohei ^a   Kurooka, Takao ^a   Iwasaki, Kenji ^c,d   Sakisaka, Toshiaki ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOKYO MEDICAL UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

C TERMINUS; CYTOPLASMIC DOMAINS; INHIBITORY ACTIVITY; MEMBRANE FUSION; MICRO-INJECTION; MOLECULAR MECHANISM; N-TERMINALS; NEUROTRANSMITTER RELEASE; SYNAPTIC VESICLE; SYNAPTOTAGMINS; TOMOSYN;

BRAIN; CELL MEMBRANES; LIPID BILAYERS;

CALCIUM;

CALPAIN; LIPOSOME; MEMBRANE PROTEIN; PROTEIN WD40; SNARE PROTEIN; SYNAPTOTAGMIN I; TOMOSYN; UNCLASSIFIED DRUG;

ACETYLCHOLINE RELEASE; AMINO TERMINAL SEQUENCE; ARTICLE; CERVICAL GANGLION; CONTROLLED STUDY; ESCHERICHIA COLI; HYDROPHOBICITY; IMMUNOPRECIPITATION; MOLECULAR DYNAMICS; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MODIFICATION; PROTEIN PURIFICATION; SYNAPTIC TRANSMISSION;

ANIMALS; CALCIUM; MEMBRANE FUSION; NERVE TISSUE PROTEINS; NEUROTRANSMITTER AGENTS; PROTEIN STRUCTURE, TERTIARY; R-SNARE PROTEINS; RATS; RATS, WISTAR; SNARE PROTEINS; SUPERIOR CERVICAL GANGLION; SYNAPTOTAGMIN I;

EID: 78650365993     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.156893     Document Type: Article

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