Regulation of ocellar specification and size by twin of eyeless and homothorax

Developmental Dynamics

Volumn 240, Issue 1, 2011, Pages 75-85

  Brockmann, Anette ^a   Domínguez Cejudo, María A ^a   Amore, Gabriele ^b   Casares, Fernando ^a  

^a Instituto de Salud Carlos III   (Spain)

^b Stazione Zoologica Anton Dohrn (SZN)   (Spain)

Author keywords

Drosophila; Eya; Hth; Retinal determination gene network; So; Toy; Visual organ development

Indexed keywords

TRANSCRIPTION FACTOR PAX6;

ARTICLE; DROSOPHILA; EYA GENE; FEEDBACK SYSTEM; GENE; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; HTH GENE; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; SO GENE; TOY GENE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BODY PATTERNING; DROSOPHILA; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; EYE; EYE PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE REGULATORY NETWORKS; HOMEODOMAIN PROTEINS; MODELS, BIOLOGICAL; MORPHOGENESIS; ORGAN SIZE; TRANS-ACTIVATORS;

EID: 78650353559     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.22494     Document Type: Article

References (52)

1. Amin A, Li Y, Finkelstein R. 1999. Hedgehog activates the EGF receptor pathway during Drosophila head development. Development 126: 2623-2630.
2. Amore G, Casares F. 2010. Size matters: the contribution of cell proliferation to the progression of the specification Drosophila eye gene regulatory network. Dev Biol 344: 569-577.
3. Baonza A, Freeman M. 2002. Control of Drosophila eye specification by Wingless signalling. Development 129: 5313-5322.
4. Bessa J, Casares F. 2005. Restricted teashirt expression confers eye-specific responsiveness to Dpp and Wg signals during eye specification in Drosophila. Development 132: 5011-5020.
5. Bessa J, Gebelein B, Pichaud F, Casares F, Mann RS. 2002. Combinatorial control of Drosophila eye development by eyeless, homothorax, and teashirt. Genes Dev 16: 2415-2427.
6. Blanco J, Seimiya M, Pauli T, Reichert H, Gehring WJ. 2009. Wingless and Hedgehog signaling pathways regulate orthodenticle and eyes absent during ocelli development in Drosophila. Dev Biol 329: 104-115.
7. Blanco J, Pauli T, Seimiya M, Udolph G, Gehring WJ. 2010. Genetic interactions of eyes absent, twin of eyeless and orthodenticle regulate sine oculis expression during ocellar development in Drosophila. Dev Biol 344: 1088-1099.
8. Bonini NM, Leiserson WM, Benzer S. 1993. The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye. Cell 72: 379-395.
9. Bonini NM, Bui QT, Gray-Board GL, Warrick JM. 1997. The Drosophila eyes absent gene directs ectopic eye formation in a pathway conserved between flies and vertebrates. Development 124: 4819-4826.
10. Briscoe J, Chen Y, Jessell TM, Struhl G. 2001. A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of sonic hedgehog in the neural tube. Mol Cell 7: 1279-1291.
11. Casares F, Mann RS. 2000. A dual role for homothorax in inhibiting wing blade development and specifying proximal wing identities in Drosophila. Development 127: 1499-1508.
12. Chao JL, Tsai YC, Chiu SJ, Sun YH. 2004. Localized Notch signal acts through eyg and upd to promote global growth in Drosophila eye. Development 131: 3839-3847.
13. Cheyette BN, Green PJ, Martin K, Garren H, Hartenstein V, Zipursky SL. 1994. The Drosophila sine oculis locus encodes a homeodomain-containing protein required for the development of the entire visual system. Neuron 12: 977-996.
14. Czerny T, Halder G, Kloter U, Souabni A, Gehring WJ, Busslinger M. 1999. twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development. Mol Cell 3: 297-307.
15. Desplan C. 1997. Eye development: governed by a dictator or a junta? Cell 91: 861-864.
16. Dominguez M, Casares F. 2005. Organ specification-growth control connection: new in-sights from the Drosophila eye-antennal disc. Dev Dyn 232: 673-684.
17. Dominguez M, Ferres-Marco D, Gutierrez-Avino FJ, Speicher SA, Beneyto M. 2004. Growth and specification of the eye are controlled independently by Eyegone and Eyeless in Drosophila melanogaster. Nat Genet 36: 31-39.
18. Donner AL, Maas RL. 2004. Conservation and non-conservation of genetic pathways in eye specification. Int J Dev Biol 48: 743-753.
19. Ekas LA, Baeg GH, Flaherty MS, Ayala-Camargo A, Bach EA. 2006. JAK/STAT signaling promotes regional specification by negatively regulating wingless expression in Drosophila. Development 133: 4721-4729.
20. Finkelstein R, Boncinelli E. 1994. From fly head to mammalian forebrain: the story of otd and Otx. Trends Genet 10: 310-315.
21. Finkelstein R, Smouse D, Capaci TM, Spradling AC, Perrimon N. 1990. The orthodenticle gene encodes a novel homeo domain protein involved in the development of the Drosophila nervous system and ocellar visual structures. Genes Dev 4: 1516-1527.
22. Friedrich M. 2006. Ancient mechanisms of visual sense organ development based on comparison of the gene networks controlling larval eye, ocellus, and compound eye specification in Drosophila. Arthropod Struct Dev 35: 357-378.
23. Gutierrez-Avino FJ, Ferres-Marco D, Dominguez M. 2009. The position and function of the Notch-mediated eye growth organizer: the roles of JAK/STAT and four-jointed. EMBO Rep 10: 1051-1058.
24. Halder G, Callaerts P, Gehring WJ. 1995. Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila. Science 267: 1788-1792.
25. Halder G, Callaerts P, Flister S, Walldorf U, Kloter U, Gehring WJ. 1998. Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development. Development 125: 2181-2191.
26. Jacobsson L, Kronhamn J, Rasmuson-Lestander A. 2009. The Drosophila Pax6 paralogs have different functions in head development but can partially substitute for each other. Mol Genet Genomics 282: 217-231.
27. Jarman AP, Sun Y, Jan LY, Jan YN. 1995. Role of the proneural gene, atonal, in formation of Drosophila chordotonal organs and photoreceptors. Development 121: 2019-2030.
28. Kenyon KL, Ranade SS, Curtiss J, Mlodzik M, Pignoni F. 2003. Coordinating proliferation and tissue specification to promote regional identity in the Drosophila head. Dev Cell 5: 403-414.
29. Kronhamn J, Frei E, Daube M, Jiao R, Shi Y, Noll M, Rasmuson-Lestander A. 2002. Headless flies produced by mutations in the paralogous Pax6 genes eyeless and twin of eyeless. Development 129: 1015-1026.
30. Kumar JP. 2009. The molecular circuitry governing retinal determination. Biochim Biophys Acta 1789: 306-314.
31. Land MF, Nilsson D-E. 2002. Animal eyes. New York: Oxford University Press.
32. Lopes CS, Casares F. 2010. hth maintains the pool of eye progenitors and its downregulation by Dpp and Hh couples retinal fate acquisition with cell cycle exit. Dev Biol 339: 78-88.
33. Mutsuddi M, Chaffee B, Cassidy J, Silver SJ, Tootle TL, Rebay I. 2005. Using Drosophila to decipher how mutations associated with human branchio-oto-renal syndrome and optical defects compromise the protein tyrosine phosphatase and transcriptional functions of eyes absent. Genetics 170: 687-695.
34. Nakano Y, Guerrero I, Hidalgo A, Taylor A, Whittle JR, Ingham PW. 1989. A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched. Nature 341: 508-513.
35. Pai CY, Kuo TS, Jaw TJ, Kurant E, Chen CT, Bessarab DA, Salzberg A, Sun YH. 1998. The Homothorax homeoprotein activates the nuclear localization of another homeoprotein, extradenticle, and suppresses eye development in Drosophila. Genes Dev 12: 435-446.
36. Pauli T, Seimiya M, Blanco J, Gehring WJ. 2005. Identification of functional sine oculis motifs in the autoregulatory element of its own gene, in the eyeless enhancer and in the signalling gene hedgehog. Development 132: 2771-2782.
37. Peng HW, Slattery M, Mann RS. 2009. Transcription factor choice in the Hippo signaling pathway: homothorax and yorkie regulation of the microRNA bantam in the progenitor domain of the Drosophila eye imaginal disc. Genes Dev 23: 2307-2319.
38. Pichaud F, Casares F. 2000. homothorax and iroquois-C genes are required for the establishment of territories within the developing eye disc. Mech Dev 96: 15-25.
39. Pignoni F, Hu B, Zavitz KH, Xiao J, Garrity PA, Zipursky SL. 1997. The eye-specification proteins So and Eya form a complex and regulate multiple steps in Drosophila eye development. Cell 91: 881-891.
40. Punzo C, Seimiya M, Flister S, Gehring WJ, Plaza S. 2002. Differential interactions of eyeless and twin of eyeless with the sine oculis enhancer. Development 129: 625-634.
41. Quiring R, Walldorf U, Kloter U, Gehring WJ. 1994. Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans. Science 265: 785-789.
42. Reynolds-Kenneally J, Mlodzik M. 2005. Notch signaling controls proliferation through cell-autonomous and non-autonomous mechanisms in the Drosophila eye. Dev Biol 285: 38-48.
43. Royet J, Finkelstein R. 1995. Pattern formation in Drosophila head development: the role of the orthodenticle homeobox gene. Development 121: 3561-3572.
44. Royet J, Finkelstein R. 1996. hedgehog, wingless and orthodenticle specify adult head development in Drosophila. Development 122: 1849-1858.
45. Serikaku MA, O'Tousa JE. 1994. sine oculis is a homeobox gene required for Drosophila visual system development. Genetics 138: 1137-1150.
46. Silver SJ, Rebay I. 2005. Signaling circuitries in development: insights from the retinal determination gene network. Development 132: 3-13.
47. Tsai YC, Sun YH. 2004. Long-range effect of upd, a ligand for Jak/STAT pathway, on cell cycle in Drosophila eye development. Genesis 39: 141-153.
48. Wang LH, Huang YT, Tsai YC, Sun YH. 2010. The role of eyg Pax gene in the development of the head vertex in Drosophila. Dev Biol 337: 246-258.
49. Wu J, Cohen SM. 2000. Proximal distal axis formation in the Drosophila leg: distinct functions of teashirt and homothorax in the proximal leg. Mech Dev 94: 47-56.
50. Yang X, Zarinkamar N, Bao R, Friedrich M. 2009. Probing the Drosophila retinal determination gene network in Tribolium (I): the early retinal genes dachshund, eyes absent and sine oculis. Dev Biol 333: 202-214.
51. Younossi-Hartenstein A, Tepass U, Hartenstein V. 1993. Embryonic origin of the imaginal discs of the head of Drosophila melanogaster. Dev Genes Evol 203: 60-73.
52. Zimmerman JE, Bui QT, Liu H, Bonini NM. 2000. Molecular genetic analysis of Drosophila eyes absent mutants reveals an eye enhancer element. Genetics 154: 237-246.