Molecular genetic analysis of Drosophila eyes absent mutants reveals an eye enhancer element

Genetics

Volumn 154, Issue 1, 2000, Pages 237-246

  Zimmerman, John E ^a,b   Bui, Quang T ^a   Liu, Haixi ^a   Bonini, Nancy M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DELETION MUTANT; DROSOPHILA; EYE DEVELOPMENT; GENE DISRUPTION; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC CONSERVATION; MOLECULAR GENETICS; PRIORITY JOURNAL;

5' UNTRANSLATED REGIONS; ALLELES; ANIMALS; BASE SEQUENCE; DNA; DNA TRANSPOSABLE ELEMENTS; DROSOPHILA; DROSOPHILA PROTEINS; ENHANCER ELEMENTS (GENETICS); EYE; EYE PROTEINS; GENE EXPRESSION REGULATION; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; SEQUENCE DELETION;

INSECTA; VERTEBRATA;

EID: 0033955091     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. AUSUBEL, F. M., 1994 Current Protocols in Molecular Biology. J. Wiley & Sons, New York.
2. BONINI, N. M., W. M. LEISERSON and S. BENZER, 1993 The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye. Cell 72: 379-395.
3. BONINI, N. M., Q. T. BUI, G. L. GRAY-BOARD and J. M. WARRICK, 1997 The Drosophila eyes absent gene directs ectopic eye formation in a pathway conserved between flies and vertebrates. Development 124: 4819-4826.
4. BONINI, N. M., W. M. LEISERSON and S. BENZER, 1998 Expression and multiple roles of the eyes absent gene in Drosophila. Dev. Biol. 129: 42-57.
5. BOYLE, M., N. BONINI and S. DINARDO, 1997 Expression and function of clift in the development of somatic gonadal precursors within the Drosophila mesoderm. Development 124: 971-982.
6. BUCHETON, A., R. PARO, H. M. SANG, A. PELISSON and D. J. FINNEGAN, 1984 The molecular basis of I-R hybrid dysgenesis in Drosophila melanogaster: identification, cloning, and properties of the I factor. Cell 38: 153-163.
7. CHEN, R., M. AMOUI, Z. ZHANG and G. MARDON, 1997 Dachshund and Eyes absent proteins form a complex and function synergistically to induce ectopic eye development in Drosophila. Cell 81: 893-904.
8. CHEN, R., G. HALDER, Z. ZHANG and G. MARDON, 1999 Signaling by the TGP-beta homolog decapentaplegic functions reiteratively within the network of genes controlling retinal cell fate determination in Drosophila. Development 126: 935-943.
9. CHEYETTE, B. N. R., P. J. GREEN, K. MARTIN, H. GARREN, V. HARTENSTEIN et al., 1994 The Drosophila sine oculis locus encodes a homeodomain-containing protein required for the development of the entire visual system. Neuron 12: 977-996.
10. CZERNY, T., G. HALDER, U. KLOTER, A. SOUABNI, W. J. GEHRING et al., 1999 twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development. Mol. Cell 3: 297-307.
11. DESPLAN, C., 1997 Eye development: governed by a dictator or a junta? Cell 91: 861-864.
12. DUNCAN, M. K., L. KOS, N. A. JENKINS, D. J. GILBERT, N. G. COPELAND et al., 1997 Eyes absent: a gene family found in several metazoan phyla. Mamm. Genome 8: 479-485.
13. FAWCETT, D. H., C. K. LISTER, E. KELLETT and D. J. FINNEGAN, 1986 Transposable elements controlling I-R hybrid dysgenesis in D. melanogaster are similar to mammalian LINEs. Cell 47: 1007-1015.
14. GEYER, P. K., C. SPANA and V. G. CORCES, 1986 On the molecular mechanism of gypsy-induced mutations at the yellow locus of Drosophila melanogaster. EMBO J. 5: 2657-2662.
15. HALDER, G., P. CALLAERTS and W. J. GEHRING, 1995 Induction of ectopic eyes by targeted expression of the eyeless gene of Drosophila. Science 267: 1788-1792.
16. HALDER, G., P. CALLAERTS, S. FLISTER, U. WALLDORF, U. KLOTER et al., 1998 Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development. Developopment 125: 2181-2191.
17. HAMMOND, K. L., I. M. HANSON, A. G. BROWN, L. A. LETTICE and R. E. HILL, 1998 Mammalian and Drosophila dachshund genes are related to the Ski proto-oncogene and are expressed in the eye and limb. Mech. Dev. 74: 121-131.
18. HAUCK, B., W. J. GEHRING and U. WALLDORF, 1999 Functional analysis of an eye specific enhancer of the eyeless gene in Drosophila. Proc. Natl. Acad. Sci. USA 96: 564-569.
19. HAZBURN, T., F. STABURA and M. MOSSING, 1997 Site-specific recognition by an isolated DNA binding domain of the sine oculis protein. Biochemistry 36: 3680-3686.
20. HAZELETT, D., M. BOURBOIS, U. WALLDORF and J. TREISMAN, 1998 decapentaplegic and wingless are regulated by eyes absent and eyegone and interact to direct the pattern of retinal differentiation in the eye disc. Development 125: 3741-3751.
21. HENIROFF, S., 1997 Nuclear organization and gene expression: homologous pairing and long-range interactions. Curr. Opin. Cell Biol. 9: 388-395.
22. KIM, J., K. JOHNSON, H. CHEN, S. CARROLL and A. LAUGHON, 1997 Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic. Nature 388: 304-308.
23. LEISERSON, W. M., N. M. BONINI and S. BENZER, 1994 Transvection at the eyes absent gene of Drosophila. Genetics 138: 1171-1179.
24. LEISERSON, W. M., S. BENZER and N. M. BONINI, 1998 Dual functions of the Drosophila eyes absent gene in the eye and embryo. Mech. Dev. 73: 193-202.
25. LEWIS, E. B., 1954 The theory and application of a new method of detecting chromosomal rearrangements in Drosophila melanogaster. Am. Nat. 88: 225-239.
26. MACLEOD, K., D. LEPRINCE and D. STEHELIN, 1992 The ets gene family. Trends Biochem. Sci. 17: 251-256.
27. MARDON, G., N. M. SOLOMON and G. M. RUBIN, 1994 Dachshund encodes a nuclear protein required for normal eye and leg development in Drosophila. Development 120: 3473-3486.
28. O'NEILL, E., I. REBAY, R. TJIAN and G. RUBIN, 1994 The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway. Cell 78: 137-147.
29. OLIVER, G., A. MAILHOS, R. WEHR, N. G. COPELAND, N. A. JENKINS et al., 1995 Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development. Development 121: 4045-4055.
30. PADGETT, R. W., R. D. ST. JOHNSTON and W. M. GELBART, 1987 A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family. Nature 325: 81-84.
31. PIGNONI, F., B. HU, K. H. ZAVITZ, J. XIAO, P. A. GARRITY et al., 1997 The eye-specification proteins So and Eya form a complex and regulate multiple steps in Drosophila eye development. Cell 91: 881-891.
32. QUIRING, R., U. WALLDORF, U. KLOTER and W. J. GEHRING, 1994 Homology of the eyeless gene of Drosophila to the small eye gene in mice and aniridia in humans. Science 265: 785-789.
33. RUTLEDGE, B. J., M. A. MORTIN, E. SCHWARZ, D. THIERRY-MIEG and M. MESELSON, 1988 Genetic interactions of modifier genes and modifiable alleles in Drosophila melanogaster. Genetics 119: 391-397.
34. SCHERER, G., C. TSCHUDI, J. PERERA, H. DELIUS and V. PIRROTTA, 1982 B104, a new dispersed repeated gene family in Drosophila melanogaster and its analogies with retroviruses. J. Mol. Biol. 157: 435-451.
35. SERIKAKU, M. A., and J. E. O'TOUSA, 1994 Sine oculis is a homeobox gene required for Drosophila visual system development. Genetics 138: 1137-1150.
36. SHEN, W., and G. MARDON, 1997 Ectopic eye development in Drosophila induced by directed dachshund expression. Development 124: 45-52.
37. SIMON, J., C. SUTTON, R. LOBELL, R. GLASER and J. LIS, 1985 Determinants of heat shock-induced chromosome puffing. Cell 40: 805-817.
38. SMITH, P. A., and V. G. CORCES, 1991 Drosophila transposable elements: mechanisms of mutagenesis and interactions with the host genome. Adv. Genet. 29: 229-300.
39. STAEHLING-HAMPTON, K., P. D. JACKSON, M. J. CLARK, A. H. BRAND and F. M. HOFFMAN, 1994 Specificity of bone morphogenetic protein-related factors: cell fate and gene expression changes in Drosophila embryos induced by decapentaplegic but not 60A. Cell Growth Differ. 5: 585-593.
40. THUMMEL, C. S., A. M. BOULET and H. D. LIPSHITZ, 1988 Vectors for Drosophila P-element-mediated transformation and tissue culture transfection. Gene 74: 445-456.
41. TREISMAN, J. E., and U. HEBERLEIN, 1998 Eye development in Drosophila: formation of the eye field and control of differentiation. Curr. Top. Dev. Biol. 39: 119-158.
42. VANDENDRIES, E. R., D. JOHNSON and R. REINKE, 1996 Orthodenticle is required for photoreceptor cell development in the Drosophila eye. Dev. Biol. 173: 243-255.
43. WU, C., 1993 Transvection, nuclear structure, and chromatin proteins. J. Cell Biol. 120: 587-590.
44. XU, P.-X., I. WOO, H. HER, D. R. BEIER and R. L. MAAS, 1997 Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in cranial placodes. Development 124: 219-231.
45. XU, P. X., X. ZHANG, S. HEANEY, A. YOON, A. M. MICHELSON et al., 1999 Regulation of Pax6 expression is conserved between mice and flies. Development 126: 383-395.
46. ZIMMERMAN, J., Q. BUI, E. STEINGRIMMSON, D. L. NAGLE, W. FU et al., 1997 Cloning and characterization of two vertebrate homologs of the Drosophila eyes absent gene. Genome Res. 7: 128-141.
47. ZIPURSKY, S. L., and G. M. RUBIN, 1994 Determination of neuronal cell fate: lessons from the R7 neuron of Drosophila. Annu. Rev. Neurosci. 17: 373-397.