Apoptosis and Bcl-2 protein expression in human placenta over the course of normal pregnancy

Journal of Veterinary Medicine Series C: Anatomia Histologia Embryologia

Volumn 39, Issue 5, 2010, Pages 426-431

  Soni, S ^a   Rath, G ^a   Prasad, C P ^a   Salhan, S ^a   Saxena, S ^b   Jain, A K ^b  

^a SAFDARJUNG HOSPITAL   (India)

^b SAFDARJUNG HOSPITAL CAMPUS   (India)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BCL 2;

ADULT; APOPTOSIS; ARTICLE; BIOSYNTHESIS; CYTOLOGY; FEMALE; FIRST TRIMESTER PREGNANCY; HUMAN; METABOLISM; PLACENTA; PREGNANCY; SECOND TRIMESTER PREGNANCY; THIRD TRIMESTER PREGNANCY; TROPHOBLAST;

ADULT; APOPTOSIS; FEMALE; HUMANS; PLACENTA; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PREGNANCY TRIMESTER, SECOND; PREGNANCY TRIMESTER, THIRD; PROTO-ONCOGENE PROTEINS C-BCL-2; TROPHOBLASTS; YOUNG ADULT;

EID: 78650334702     PISSN: 03402096     EISSN: 14390264     Source Type: Journal    
DOI: 10.1111/j.1439-0264.2010.01012.x     Document Type: Article

References (24)

1. Amato, P., I. Zwain, and J. Reed, 1996: Expression of BCL-2 & bax in human placenta. J. Soc. Gynecol. Investig. 3, 226A.
2. Austgulen, R., L. Chedwick, C. V. Isaksen, L. Vatten, and C. Craven, 2002: Trophoblast apoptosis in human placenta at term as detected by expression of a cytokeratin 18 degradation product of caspase. Arch. Pathol. Lab. Med. 126, 1480-1486.
3. Daher, S., A. J. Guimarães, R. Mattar, M. M. S. Ishigai, E. G. Barreiro, and E. Bevilacqua, 2008: Bcl-2 and Bax expressions in pre-term, term and post-term placentas. Am. J. Reprod. Immunol. 60, 172-178.
4. Doonan, F., and T. G. Cotter, 2008: Morphological assessment of apoptosis. Methods 44, 200-204.
5. Fadeel, B., B. Zhivotovsky, and S. Orrenius, 1999: All along the watchtower: on the regulation of apoptosis regulators. FASEB J. 13, 1647-1657.
6. Halperin, R., S. Peller, M. Rotschild, I. Bukovsky, and D. Schneider, 2000: Placental apoptosis in normal and abnormal pregnancies. Gynecol. Obstet. Invest. 50, 84-87.
7. Huppertz, B., M. Kadyrov, and J. C. Kingdom, 2006: Apoptosis and its role in the trophoblast. Am. J. Obstet. Gynecol. 195, 29-39.
8. Ishihara, N., H. Matsuo, H. Murakoshi, J. Laoag-Fernandez, T. Samoto, and T. Maruo, 2000: Changes in proliferative potential, apoptosis and Bcl-2 protein expression in cytotrophoblasts and syncytiotrophoblast in human placenta over the course of pregnancy. Endocr. J. 47, 317-327.
9. Jeong, S-Y., and D-W. Seol, 2008: The role of mitochondria in apoptosis. BMB Rep. 41, 11-22.
10. Kadyrov, M., P. Kaufmann, and B. Huppertz, 2001: Expression of a cytokeratin 18 neo-epitope is a specific marker for trophoblast apoptosis in human placenta. Placenta 22, 44-48.
11. Kerr, J. F., A. H. Wyllie, and A. R. Currie, 1972: Apoptosis: a basic biological phenomenon with wide ranging implications in kinetics. Br. J. Cancer 29, 239-257.
12. Kim, C. J., Y. J. Choe, B. H. Yoon, C. W. Kim, and J. G. Chi, 1995: Patterns of BCL-2 expression in the placenta. Pathol. Res. Pract. 191, 1239-1244.
13. Labi, V., F. Grespi, F. Baumgartner, and A. Villunger, 2008: Targeting the Bcl-2-regulated apoptosis pathway by BH3 mimetics: a breakthrough in anticancer therapy? Cell. Death. Differ. 15, 977-987.
14. Lu, Q. L., R. Poulsom, L. Wong, and A. M. Hanby, 1993: Bcl-2 expression in adult and embryonic non-haematopoietic tissues. J. Pathol. 169, 431-437.
15. Marzioni, D., J. Muhlhauser, C. Crescimanno, M. Banita, C. Pierleoni, and M. Castellucci, 1998: BCL-2 expression in the human placenta & its correlation with fibrin deposits. Hum. Reprod. 6, 1717-1722.
16. Murakoshi, H., H. Matsuo, J. B. Laoag-Fernandez, T. Samoto, and T. Maruo, 2003: Expression of Fas/Fas-Ligand, Bcl-2 protein and apoptosis in extravillous trophoblast along invasion to the decidua in human term placenta. Endocr. J. 50, 199-207.
17. Pongcharoen, S., J. N. Bulmer, and R. F. Searle, 2004: No evidence for apoptosis of decidual leucocytes in normal and molar pregnancy: implications for immune privilege. Clin. Exp. Immunol. 138, 330-336.
18. Qiao, S., T. Nagasaka, T. Harada, and N. Nakashima, 1998: p53, Bax and Bcl-2 expression, and apoptosis in gestational trophoblast of complete hydatidiform mole. Placenta 19, 361-369.
19. Ratts, V. S., X. J. Tao, C. B. Webster, P. E. Swanson, S. D. Smith, P. Brownbill, S. Krajewski, J. C. Reed, J. L. Tilly, and D. M. Nelson, 2000: Expression of BCL-2, BAX and BAK in the trophoblast layer of the term human placenta: a unique model of apoptosis within a syncytium. Placenta 21, 361-366.
20. Sgarbosa, F., L. F. Barbisan, M. A. M. Brasil, E. Costa, I. M. P. Calderon, C. R. Goncalves, E. Bevilacqua, and M. V. C. Rudge, 2006: Changes in apoptosis and Bcl-2 expression in human hyperglycemic, term placental trophoblast. Diabetes Res. Clin. Pract. 73, 143-149.
21. Smith, S. C., P. N. Baker, and E. M. Symonds, 1997: Placental apoptosis in normal human pregnancy. Am. J. Obstet. Gynecol. 177, 57-65.
22. Straszewski-Chavez, S. L., V. M. Abrahams, and G. Mor, 2005: The role of apoptosis in the regulation of trophoblast survival and differentiation during pregnancy. Endocr. Rev. 26, 877-897.
23. Tanir, H. M., T. Sener, S. Artan, B. Kaytaz, F. Sahin-Mutlu, and M. E. Ozen, 2005: Programmed cell death (apoptosis) in placentas from normal pregnancy and pregnancy complicated by term (t) and preterm (p) premature rupture of membranes (PROM). Arch. Gynecol. Obstet. 273, 98-103.
24. Thomenius, M.J., and C.W. Distelhorst, 2003: Bcl-2 on the endoplasmic reticulum: protecting the mitochondria from a distance. J. Cell Sci. 116, 4493-4499.