BCL-2 expression in the human placenta and its correlation with fibrin deposits

Human Reproduction

Volumn 13, Issue 6, 1998, Pages 1717-1722

  Marzioni, D ^a   Muhlhauser J ^b,c   Crescimanno, C ^c,d   Banita, M ^a   Pierleoni, C ^a,c   Castellucci, M ^a,c,e  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^b LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

^c RWTH AACHEN UNIVERSITY   (Germany)

^d UNIVERSITY OF VERONA   (Italy)

^e UNIVERSITY OF TURIN   (Italy)

Author keywords

BCL 2; Fibrin; Immunohistochemistry; Microscopy; Placenta

Indexed keywords

FIBRIN; PLACENTA PROTEIN; PROTEIN BCL 2;

ARTICLE; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTROPHOBLAST; EXTRACELLULAR MATRIX; FEMALE; FETUS DEVELOPMENT; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MESENCHYME CELL; PLACENTA; PLACENTA FUNCTION; PROTEIN EXPRESSION; SYNCYTIOTROPHOBLAST; THIRD TRIMESTER PREGNANCY; TROPHOBLAST;

EID: 2642712517     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/13.6.1717     Document Type: Article

References (43)

1. Aharoni, D., Meiri, I., Atzmon, R. et al. (1996) Differential effect of components of the extracellular matrix on differentiation and apoptosis. Curr. Biol., 7, 43-51.
2. Benirschke, K. and Kaufmann, R (1995) Pathology of the Human Placenta, 3rd edn. Springer Verlag, New York.
3. Boyd, J.D. and Hamilton, W.J. (1970) The Human Placenta. Heffer. Cambridge.
4. Castellucci, M. and Kaufmann, P. (1995) Basic structure of the villous trees. In Benirschke, K. and Kaufmann, P. (eds), Pathology of the Human Placenta, 3rd edn. Springer Verlag, New York, pp. 57-115.
5. Castellucci, M., Scheper, M., Scheffen, I. et al. (1990) The development of the human placental villous tree. Anat. Embryol., 181, 117-128.
6. Castellucci, M., Classen-Linke I., Mühlhauser, J. et al. (1991) The human placenta: a model for tenascin expression. Histochemistry, 95, 449-458.
7. Castellucci, M., Mühlhauser, J., Pierleoni, C. et al., (1993) Bcl-2 expression in the human trophoblast. Anat. Anz., 175 (Suppl.), 38-39.
8. Chandler, D., El-Naggar, A.K., Brisbay, S. et al. (1994) Apoptosis and expression of the bcl-2 proto-oncogene in the fetal and adult human kidney: evidence for the contribution of bcl-2 expression to renal carcinogenesis. Hum. Pathol., 25, 789-796.
9. De Franco, A.L. (1992) Bcl-2 to the rescue. Immune Dev., 2, 95-97.
10. Fox, H. (1975) Morphological pathology of the placenta. In Gruenwald, P. (ed.), The Placenta and its Maternal Supply Line: Effects of Insufficiency on the Fetus. MTP, Lancaster, pp. 197-220.
11. Fox, H. (1978) Pathology of the Placenta. Saunders, Philadelphia.
12. Frank, H-G., Malekzadeh, F., Kertschanska, S. et al. (1994) Immunohistochemistry of two different types of placental fibrinoid. Acta Anatomica, 150, 55-68.
13. Frisch, S.M. and Francis H. (1994) Disruptions of epithelial cell-matrix, interactions induces apoptosis. J. Cell Biol., 124, 619-626.
14. Gille, J., Börner, P., Reinecke, J. et al. (1974) Über die Fibrinoidablagerungen in den Endzotten der menschlichen Placenta. Archiv für Gynäkologie, 217, 263-271.
15. Harmsel, B.T., Smedts F., Kuijpers J. et al. (1996) Bcl-2 immunoreactivity increases with severity of cin: a study of normal cervical epithelia, cin, and cervical carcinoma. J. Pathol., 179, 26-30.
16. Hockenbery, D.M., Zutter, M., Hickey W. et al. (1991) Bcl-2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc. Natl Acad. Sci. USA, 88, 6961-6965.
17. Huffman, B. and Liebermann, D.A. (1994) Molecular controls of apoptosis: differentiation/growth arrest primary response genes, proto-oncogenes, and tumor suppressor genes as positive and negative modulators. Oncogene, 9, 1807-1812.
18. Hsu, S.M. and Raine, L. (1981) Protein A, avidin and biotin in immunohistochemistry. J. Histochem. Cytochem., 29, 1349-1353.
19. Kaufmann, P. and Castellucci, M. (1995) Development and anatomy of the placenta. In Fox, H. (ed.), Haines and Taylor's Obstetrical and Gynaecological Pathology. Churchill Livingstone, Edinburgh, pp. 1437-1476.
20. Kaufmann, P., Huppertz, B. and Frank, H-G. (1996) The fibrinoids of the human placenta: origin, composition and functional relevance. Ann. Anat., 178, 485-501.
21. Kernohan, N.M. and Cox, L.S. (1996) Regulation of apoptosis by Bcl-2 and its related proteins: immunochemical challenges and therapeutic implications. J. Pathol., 179, 1-3.
22. Kosanke, G., Castellucci, M., Kaufmann, P. et al. (1993) Branching patterns of human placenta villous trees: perspectives of topological analysis. Placenta, 14, 591-604.
23. Krajewski, S., Krajewska, M., Shabaik, A. et al. (1994) Immunohistochemical determination of in vivo distribution of bax, a dominant inhibitor of bcl-2. Am. J. Pathol., 145, 1323-1336.
24. Krajewski, S., Krajewska, M. and Reed, J.C. (1996) Immunohistochemical analysis of in vivo patterns of bak expression, a proapoptotic member of Bcl-2 protein family. Cancer Res., 56, 2849-2855.
25. Lea, R.G., al-Sharekh, N., Tulppala, M. et al. (1997) The immunolocalization of bcl-2 at the maternal - fetal interface in healthy and failing pregnancies. Hum. Reprod., 12, 153-158.
26. Lu, Q-L., Poulsom, R., Wong, L. et al. (1993) Bcl-2 expression in adult and embryonic non-haematopoietic tissues. J. Pathol., 169, 431-437.
27. Lu, Q-L., Abel, P., Foster, C.S. et al. (1996) Bcl-2: role in epithelial differentiation and oncogenesis. Hum. Pathol, 27, 102-110.
28. Marzioni, D., Mühlhauser, J., Verdenelli, F. et al. (1997) Bax. Bcl-2 and fibrin expressions in the human placenta. It. J. Anat. Embryol., 102 (Suppl.), 205.
29. McLaren, J., Prentice, A., Charnock-Jones, D.S. et al. (1997) Immunolocalization of the apoptosis regulating proteins BCL-2 and BAX in human endometrium and isolated peritoneal fluid macrophages in endometriosis. Hum. Reprod., 12, 146-152.
30. Meredith, J.E., Fazeli, B. and Schwartz, M.A. (1993) The extracellular matrix as a cell survival factor. Mol. Biol. Cell, 4, 953-961.
31. Mühlhauser, J., Crescimanno, C., Kaufmann, P. et al. (1993) Differentiation and proliferation patterns in human trophoblast revealed by c-erbB-2 oncogene product and EGF-R. J. Histochem. Cytochem., 41, 165-173.
32. Mühlhauser, J., Crescimanno, C., Kasper, M. et al. (1995) Differentiation of the human trophoblast populations involves alterations in cytokeratin patterns. J. Histochem, Cytochem., 43, 579-589.
33. Nelson, D.M. (1996) Apoptotic changes occur in syncytiotrophoblast of human placental villi where fibrin type fibrinoid is deposited at discontinuities in the villous trophoblast. Placenta, 17, 387-391.
34. Nelson, D.M., Crouch, E.C., Curran, E.M. et al. (1990) Trophoblast interaction with fibrin matrix. Epithelialization of perivillous fibrin deposits as a mechanism for villous repair in the human placenta. Am. J. Pathol., 136, 855-865.
35. Pezzella, F., Tse, A.G.D., Cordell. J.L. et al. (1990) Expression of the bcl-2 oncogene protein is not specific for the 14; 18 chromosomal translocation. Am. J. Pathol., 137, 225-232.
36. Richart, R. (1961) Studies of placental morphogenesis. J. Med., 106, 829-831.
37. Sakuragi, N., Matsuo, H., Coukos, G. et al. (1994) Differentiation dependent expression of the bcl-2 proto-oncogene in the human trophoblast lineage. J. Soc. Gynecol Invest., 1, 164-172.
38. Thiet, M.S., Suwanvanichkij, V., Kwok, C. et al. (1995) DNA laddering, consistent with programmed cell death, is a normal finding in human placentas. J. Obstet., 172, 272.
39. Toth, F., Paal, M., Nemeth, J. et al. (1973) Histochemical studies of fibrinoid, mucopolysaccharides and chorionic gonadotrophin in the normal and pathologic human placenta. Acta Morphol. Acad. Sci. Hung., 21, 89-104.
40. Uckan, D., Steele, A., Wang, B.Y. et al. (1997) Trophoblasts express Fas ligand: a proposed mechanism for immune privilege in placenta and maternal invasion. Mol. Hum. Reprod., 3, 655-662.
41. Wilkin, P. (1965) Pathologie du placenta. Masson, Paris.
42. Yasuda, M., Umemura, S., Osamura, R.Y. et al. (1995) Apoptotic cells in the human endometrium and placental villi: pitfalls in applying the TUNEL method. Arch. Histol. Cytol, 58, 185-190.
43. Zhang, Z., Vuori, K., Reed, J.C. et al. (1995) The α5β1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression. Proc. Natl Acad. Sci. USA, 92, 6161-6165.