Triterpenoids and iridoid glycosides from Gentiana dahurica

Helvetica Chimica Acta

Volumn 93, Issue 12, 2010, Pages 2439-2447

  Fan, Hui ^a   Zang, Yi ^a   Zhang, Yi ^b   Zhang, Hong Feng ^b   Zhao, Zheng ^a   Hu, Jin Feng ^a  

^a East China Normal University   (China)

^b EAST CHINA NORMAL UNIVERSITY   (China)

Author keywords

Cytotoxic activity; Gentiana dahurica; Glycosides; Iridoid glycosides; Triterpenoids

Indexed keywords

CYTOTOXIC ACTIVITIES; GENTIANA DAHURICA; GLYCOSIDES; IRIDOID GLYCOSIDES; TRITERPENOIDS;

CELL CULTURE; CYTOTOXICITY; METABOLITES;

SUGARS;

1 BETA,2 ALPHA,3 ALPHA 24 TETRAHYDROXYOLEAN 12 EN 28 OIC ACID; 1 BETA,2 ALPHA,3 ALPHA 24 TETRAHYDROXYURS 12 EN 28 OIC ACID; 1 BETA,2 ALPHA,3 ALPHA,24 TETRAHYDROXYURSA 12,20(30) DIEN 28 OIC ACID; 2 ALPHA HYDROXYURSOLIC ACID; 2 ALPHA,3 BETA,24 TRIHYDROXYURS 12 EN 28 OIC ACID; 3 BETA,24 DIHYDROXYURS 12 EN 28 OIC ACID; 3' ACETYLGENTIOPICROSIDE; 6 O ACETYLGENTIOPICROSIDE 5 ETHENYL 5,6 DIHYDRO 1 OXO 1H,3H PYRANO[3,4 C]PYRAN 6 YL 6 O ACETYL BETA DEXTRO GLUCOPYRANOSIDE; 6 O BETA DEXTRO GLUCOPYRANOSYL GENTIOPICROSIDE; 6' O ACETYLGENTIOPICROSIDE; GENTIOPICRIN; IRIDOID; LOGANIC ACID; MASLINIC ACID; TRITERPENOID; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; GENTIAN; GENTIANA DAHURICA; HUMAN; HUMAN CELL; IC 50; PRIORITY JOURNAL;

EID: 78650318982     PISSN: 0018019X     EISSN: 15222675     Source Type: Journal    
DOI: 10.1002/hlca.201000095     Document Type: Article

References (34)

1. Jiangsu New Medical College, 'A Dictionary of the Traditional Chinese Medicine', Shanghai Science and Technology Press, Shanghai, 1986, p. 1764.
2. H. Y. Hsu, Y. P. Chen, S. J. Shen, C. S. Hsu, C. C. Chen, H. C. Chang, 'Oriental Materia Medica: A Concise Guide. Keats Publishing', New Canaan, Connecticut, 1986, p. 334.
3. Q. L. Chen, Z. Y. Shi, G. Z. Tu, W. J. Sun, China J. Chin. Mater. Med. 2005, 30, 1519 (Chem. Abstr. 2007, 147, 318314).
4. R. X. Tan, J.-L. Wolfender, L. X. Zhang, W. G. Ma, N. Fuzzati, A. Marston, K. Hostettmann, Phytochemistry 1996, 42, 1305.
5. M. S. Y. Khan, A. A. Anees, K. Javed, Asian J. Chem. 1997, 9, 27.
6. J. Sun, W. H. Xu, Y. H. Wang, Y. J. Han, G. C. Chen, Chin. J. Anal. Lab. 2008, 27, 51 (Chem. Abstr. 2009, 151, 273125).
7. J. Yang, J. Ma, D. X. Zhou, L. He, Chin. Tradit. Herb. Drugs 2006, 37, 187.
8. J. Sun, F. Li, W. Xu, G. Zhou, J. You, G. Chen, Chromatographia 2009, 70, 1627.
9. S.-B. Wu, Y.-P. Ji, J.-J. Zhu, Y. Zhao, G. Xia, Y.-H. Hu, J.-F. Hu, Steroids 2009, 74, 761.
10. S.-B. Wu, F. Pang, Y. Wen, H.-F. Zhang. Z. Zhao, J.-F. Hu, Planta Med. 2010, 76, 82.
11. H. A. Jung, H. Y. Chung, S. S. Kang, S. K. Hyun, H. S. Kang, J. S. Choi, Arch. Pharmacal Res. 2005, 28, 1127.
12. H. El Lahlou, N. Hirai, M. Tsuda, H. Ohigashi, Phytochemistry 1999, 52, 623.
13. Y. H. Xiao, A. L. Zhang, G. L. Zhang, Nat. Prod. Res. Dev. 2007, 19, 978.
14. S. Taniguchi, Y. Imayoshi, E. Kobayashi, Y. Takamatsu, H. Ito, T. Hatano, H. Sakagami, H. Tokuda, H. Nishino, D. Sugita, S. Shimura, T. Yoshida, Phytochemistry 2002, 59, 315.
15. Y. Shi, H. L. Wang, B. R. Ma, Chin. Tradit. Herb. Drugs 1993, 24, 386.
16. C. A. Boros, F. R. Stermitz, J. Nat. Prod. 1991, 54, 1173.
17. R. Kakuda, T. Iijima, Y. Yaoita, K. Machida, M. Kikuchi, J. Nat. Prod. 2001, 64, 1574.
18. C. A. Boros, F. R. Stermitz, J. Nat. Prod. 1990, 53, 1055.
19. Y.-J. Zhang, C.-R. Yang, Phytochemistry 1994, 36, 997.
20. M. Xu, M. Zhang, Y.-J. Zhang, C.-R. Yang, Helv. Chim. Acta 2009, 92, 321.
21. Q.-X. Wu, X. Liu, Y.-P. Shi, Chem. Biodiversity 2007, 4, 175.
22. Y. Toriumi, R. Kakuda, M. Kikuchi, Y. Yaoita, M. Kikuchi, Chem. Pharm. Bull. 2003, 51, 89.
23. J.-A. Kim, N. S. Son, J. K. Son, Y. D. Jahng, H. W. Chang, T. S. Jang, M. K. Ma, S.-H. Lee, Arch. Pharmacal Res. 2009, 32, 863.
24. M. Kikuchi, R. Kakuda, M. Kikuchi, Y. Yaoita, J. Nat. Prod. 2005, 68, 751.
25. D. Krstić, T. Janković, I. Aljančić, K. Åavikin-Fodulović, N. Menković, S. Milosavljević, Biochem. Syst. Ecol. 2004, 32, 937.
26. J. M. Li, F. A. Li, X. Y. Li, H. Zhang, Q. J. Wei, Z. X. Wang, L. Q. Mi, C. N. Xiao, Nat. Prod. Res. Dev. 2004, 16, 225.
27. M. Wu, P. Wu, M. Liu, H. Xie, Y. Jiang, X. Wei, Phytochemistry 2009, 70, 746.
28. H. Yin, Q. Zhao, F.-M. Sun, T. An, Phytomedicine 2009, 16, 793.
29. H. Yoon, R. H. Liu, J. Agric. Food Chem. 2008, 56, 8412.
30. X. He, R. H. Liu, J. Agric. Food Chem. 2007, 55, 4366.
31. D. Wang, M. Xia, Z. Cui, Chem. Pharm. Bull. 2006, 54, 775.
32. T. Mosmann, J. Immunol. Methods 1983, 65, 55.
33. M. Colombain, V. Goll, F. Muyard, C. Girard, F. Bévalot, L. Richert, Planta Med. 2001, 67, 644.
34. R. Bruggisser, K. von Daeniken, G. Jundt, W. Schaffner, H. Tullberg-Reinert, Planta Med. 2002, 68, 445.