A bioassay using the human hepatoblastoma cell line HepG2 for detecting phototoxicity of furocoumarins

Planta Medica

Volumn 67, Issue 7, 2001, Pages 644-646

  Colombain, M ^a   Goll, V ^a   Muyard, F ^a   Girard, C ^a   Bevalot F ^a   Richert, L ^a  

^a UNIVERSITÉ DE FRANCHE COMTÉ   (France)

Author keywords

Cytotoxicity; Furocoumarins; HepG2 cell line; Phototoxicity

Indexed keywords

FUROCOUMARIN DERIVATIVE; HERACLENOL; METHOXSALEN; PENTOSALEN; PEUCEDANIN; TRICHOCLIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CYTOTOXICITY; DRUG STRUCTURE; HEPATOBLASTOMA; HUMAN; HUMAN CELL; PHOTOTOXICITY; QUANTITATIVE ASSAY;

CELL LINE; CELL SURVIVAL; COUMARINS; CYTOTOXINS; HUMANS; PHOTOCHEMISTRY; PLANT EXTRACTS; PSORALENS; RUTACEAE; SENSITIVITY AND SPECIFICITY; TOXICITY TESTS; TUMOR CELLS, CULTURED; ULTRAVIOLET RAYS;

EID: 0034805328     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2001-17364     Document Type: Article

References (12)

1. Recent advances in psoralen phototoxicity mechanism
2. An ultrasensitive bioassay for the detection of furocoumarins and other photosensitizing molecules
3. Thin-layer chromatographic assay of photoactive compounds (furocoumarins) using the fungus Penicillium expansum as a test organism
4. The Candida test for phototoxicity
5. A quantitative in vitro assay for the evaluation of phototoxic potential of topically applied materials
6. Phototoxicität und photomutagenität von furocumarinen und furocumarindrogen bei chlamydomonas reinhardii
7. A biossay using Artemia salina for detecting phototoxicity of plant coumarins
8. Mutagenicity and toxicity of furocoumarins: Comparative investigations in two test systems
9. Metabolic reactions in vitro of psoralens with liver and epidermis
10. Photochemotherapy of skin-diseases: Comparative studies on the photochemical and photobiological properties of various mono- and bifunctional agents
11. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
12. Evaluation of tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing