Modified polyethyleneimine with histidine-lysine short peptides as gene carrier

Cancer Gene Therapy

Volumn 18, Issue 1, 2011, Pages 12-19

  Hashemi, M ^a   Parhiz, B H ^a   Hatefi, A ^b   Ramezani, M ^a  

^a MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

histidine; lysine; non viral vector; polyethyleneimine

Indexed keywords

ALKYL GROUP; AMINE; CARBOXYL GROUP; EDOXUDINE; ETHYLENEDIAMINE; GESTONORONE CAPROATE; HEXANOIC ACID; HISTIDINE; LUCIFERASE; LYSINE; PEPTIDE; POLYETHYLENEIMINE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; DRUG STRUCTURE; DRUG TOXICITY; DRUG USE; GENETIC TRANSFECTION; HETEROZYGOTE; LIPOPHILICITY; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; REPORTER GENE;

ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; GENETIC VECTORS; HISTIDINE; HUMANS; LYSINE; MICE; PEPTIDES; POLYETHYLENEIMINE; TRANSFECTION;

MURINAE;

EID: 78650311464     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/cgt.2010.57     Document Type: Article

References (23)

1. Jolly D. Viral vector systems for gene therapy. Cancer Gene Ther 1994; 1: 51-64.
2. Mintzer MA, Simanek EE. Non-viral vectors for gene delivery. Chem Rev 2009; 109: 259-302.
3. Parker AL, Newman C, Briggs S, Seymour L, Sheridan PJ. Non-viral gene delivery: techniques and implications for molecular medicine. Expert Rev Mol Med 2003; 5: 1-15.
4. Wiethoff CM, Middaugh CR. Barriers to non-viral gene delivery. J Pharm Sci 2003; 92: 203-217.
5. Boussif O, Lezoualc'h F, Zanta MA, Mergny MD, Scherman D, Demeneix B et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethyleneimine. Proc Natl Acad Sci USA 1995; 92: 7297-7301.
6. Lungwitz U, Breunig M, Blunk T, Gopferich A. Polyethy-leneimine-based non-viral gene delivery systems. Eur J Pharm Biopharm 2005; 60: 247-266.
7. Neu M, Fischer D, Kissel T. Recent advances in rational gene transfer vector design based on poly (ethyleneimine) and its derivatives. J Gene Med 2005; 7: 992-1009.
8. Godbey WT, Wu KK, Mikos AG. Size matters: molecular weight affects the efficiency of poly(ethyleneimine) as a gene delivery vehicle. J Biomed Mater Res 1999; 45: 268-275.
9. 0s delivery of plasmid DNA into mammalian cells. Proc Natl Acad Sci USA 2002; 99: 14640-14645.
10. Ogris M, Steinlein P, Kursa M, Mechtler K, Kircheis R, Wagner E. The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells. Gene Ther 1998; 5: 1425-1433.
11. Ahn CH, Chae SY, Bae YH, Kim SW. Biodegradable poly(ethyleneimine) for plasmid DNA delivery. J Control Release 2002; 80: 273-282.
12. Abdallah B, Hassan A, Benoist C, Goula D, Behr JP, Demeneix BA. A powerful non-viral vector for in vivo gene transfer into the adult mammalian brain: polyethyleneimine. Hum Gene Ther 1996; 7: 1947-1954.
13. Kleemann E, Neu M, Jekel N, Fink L, Schmehl T, Gessler T et al. Nano-carriers for DNA delivery to the lung based upon a TAT-derived peptide covalently coupled to PEG-PE. J Control Release 2005; 109: 299-316.
14. Kunath K, Merdan T, Hegener O, Haberlein H, Kissel T. Integrin targeting using RGD-PEI conjugates for in vitro gene transfer. J Gene Med 2003; 5: 588-599.
15. Lee H, Jeong JH, Park TG. A new gene delivery formulation of polyethyleneimine/DNA complexes coated with PEG conjugated fusogenic peptide. J Control Release 2001; 76: 183-192.
16. Li D, Wang QQ, Tang GP, Huang HL, Shen FP, Li JZ et al. Receptor-mediated gene delivery using polyethyleneimine (PEI) coupled with polypeptides targeting FGF receptors on cells surface. J Zhejiang Univ SCIENCE B 2006; 7: 906-911.
17. Dehshahri A, Oskuee RK, Shier WT, Hatefi A, Ramezani M. Gene transfer efficiency of high primary amine content, hydrophobic, alkyl-oligoamine derivatives of polyethylenei-mine. Biomaterials 2009; 30: 4187-4194.
18. Oskuee RK, Dehshahri A, Shier WT, Ramezani M. Alkylcarboxylate grafting to polyethyleneimine: a simple approach to producing a DNA nanocarrier with low toxicity. J Gene Med 2009; 11: 921-932.
19. Canine BF, Wang Y, Hatefi A. Evaluation of the effect of vector architecture on DNA condensation and gene transfer efficiency. J Control Release 2008; 129: 117-123.
20. Snyder SL, Sobocinski PZ. An improved 2, 4, 6-trinitroben-zenesulfonic acid method for the determination of amines. Anal Biochem 1975; 64: 284-288.
21. Leng Q, Goldgier L, Zhu J, Cambell P, Ambulos N, Mixon AJ. Histidine-lysine peptides as carrier of carrier of nucleic acids. Drug News Perspect 2007; 20: 77-86.
22. Midoux P, Pichon C, Yaouanc JJ, Jaffres PA. Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imida-zole as nucleic acids carriers. Br J Pharmacol 2009; 157: 166-178.
23. Tu Z, Volk M, Shah K, Clerkin K, Liang FJ. Constructing bioactive peptides with pH-dependent activities. Peptides 2009; 30: 1523-1528.