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Volumn 48, Issue 1, 2011, Pages 152-159

Neuroblastoma and bone metastases: Clinical significance and prognostic value of Dickkopf 1 plasma levels

Author keywords

Bone metastasis; Dickkopf 1; Neuroblastoma; Osteoblast; Wnt pathway

Indexed keywords

DICKKOPF 1 PROTEIN; DOXORUBICIN; SMALL INTERFERING RNA;

EID: 78650310298     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2010.06.028     Document Type: Article
Times cited : (29)

References (50)
  • 1
    • 40649090942 scopus 로고    scopus 로고
    • Molecular mechanisms and treatment of bone metastasis
    • Clines G.A., Guise T.A. Molecular mechanisms and treatment of bone metastasis. Expert Rev Mol Med 2008, 10:e7.
    • (2008) Expert Rev Mol Med , vol.10
    • Clines, G.A.1    Guise, T.A.2
  • 2
    • 38649093611 scopus 로고    scopus 로고
    • Neuroblastoma: biology, prognosis, and treatment
    • Park J.R., Eggert A., Caron H. Neuroblastoma: biology, prognosis, and treatment. Pediatr Clin North Am 2008, 55:97-120.
    • (2008) Pediatr Clin North Am , vol.55 , pp. 97-120
    • Park, J.R.1    Eggert, A.2    Caron, H.3
  • 3
    • 0027239723 scopus 로고
    • Revisions of the international criteria for neuroblastoma diagnosis, staging and response to treatment
    • Brodeur G.M., Pritchard J., Berthold F., Carlsen N.L., Castel V., Castelberry R.P., et al. Revisions of the international criteria for neuroblastoma diagnosis, staging and response to treatment. J Clin Oncol 1993, 11:1466-1477.
    • (1993) J Clin Oncol , vol.11 , pp. 1466-1477
    • Brodeur, G.M.1    Pritchard, J.2    Berthold, F.3    Carlsen, N.L.4    Castel, V.5    Castelberry, R.P.6
  • 4
    • 0038697907 scopus 로고    scopus 로고
    • Advances in the diagnosis and treatment of neuroblastoma
    • Weinstein J.L., Katzenstein H.M., Cohn S.L. Advances in the diagnosis and treatment of neuroblastoma. Oncologist 2003, 8:278-292.
    • (2003) Oncologist , vol.8 , pp. 278-292
    • Weinstein, J.L.1    Katzenstein, H.M.2    Cohn, S.L.3
  • 5
    • 0031911489 scopus 로고    scopus 로고
    • Multivariate analysis of risk factors in Stage 4 neuroblastoma patients over the age of one year treated with megatherapy and stem-cell transplantation: a report from the European Bone Marrow Transplantation Solid Tumor Registry
    • Ladenstein R., Philip T., Lasset C., Hartmann O., Garaventa A., Pinkerton R., et al. Multivariate analysis of risk factors in Stage 4 neuroblastoma patients over the age of one year treated with megatherapy and stem-cell transplantation: a report from the European Bone Marrow Transplantation Solid Tumor Registry. J Clin Oncol 1998, 16:953-965.
    • (1998) J Clin Oncol , vol.16 , pp. 953-965
    • Ladenstein, R.1    Philip, T.2    Lasset, C.3    Hartmann, O.4    Garaventa, A.5    Pinkerton, R.6
  • 6
    • 38849141590 scopus 로고    scopus 로고
    • Stem cell transplantation for neuroblastoma
    • Fish J.D., Grupp S.A. Stem cell transplantation for neuroblastoma. Bone Marrow Transplant 2008, 41:159-165.
    • (2008) Bone Marrow Transplant , vol.41 , pp. 159-165
    • Fish, J.D.1    Grupp, S.A.2
  • 7
    • 0035866399 scopus 로고    scopus 로고
    • Receptor activator of nuclear factor kB ligand (RANKL) is a key molecule of osteoclast formation for bone metastasis in a newly developed model of human neuroblastoma
    • Michigami T., Ihara-Watanabe M., Yamazaki M., Ozono K. Receptor activator of nuclear factor kB ligand (RANKL) is a key molecule of osteoclast formation for bone metastasis in a newly developed model of human neuroblastoma. Cancer Res 2001, 61:1637-1644.
    • (2001) Cancer Res , vol.61 , pp. 1637-1644
    • Michigami, T.1    Ihara-Watanabe, M.2    Yamazaki, M.3    Ozono, K.4
  • 8
    • 4143057125 scopus 로고    scopus 로고
    • In vitro blockade of receptor activator of nuclear factor-kB ligand prevents osteoclastogenesis induced by neuroblastoma cells
    • Granchi D., Amato I., Battistelli L., Avnet S., Capaccioli S., Papucci L., et al. In vitro blockade of receptor activator of nuclear factor-kB ligand prevents osteoclastogenesis induced by neuroblastoma cells. Int J Cancer 2004, 111:829-838.
    • (2004) Int J Cancer , vol.111 , pp. 829-838
    • Granchi, D.1    Amato, I.2    Battistelli, L.3    Avnet, S.4    Capaccioli, S.5    Papucci, L.6
  • 9
    • 13944258987 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells provide an alternate pathway of osteoclast activation and bone destruction by cancer cells
    • Sohara Y., Shimada H., Minkin C., Erdreich-Epstein A., Nolta J.A., DeClerck Y.A. Bone marrow mesenchymal stem cells provide an alternate pathway of osteoclast activation and bone destruction by cancer cells. Cancer Res 2005, 65:1129-1135.
    • (2005) Cancer Res , vol.65 , pp. 1129-1135
    • Sohara, Y.1    Shimada, H.2    Minkin, C.3    Erdreich-Epstein, A.4    Nolta, J.A.5    DeClerck, Y.A.6
  • 10
    • 23944432868 scopus 로고    scopus 로고
    • Mechanisms of bone invasion and metastasis in human neuroblastoma
    • Sohara Y., Shimada H., DeClerck Y.A. Mechanisms of bone invasion and metastasis in human neuroblastoma. Cancer Lett 2005, 228:203-209.
    • (2005) Cancer Lett , vol.228 , pp. 203-209
    • Sohara, Y.1    Shimada, H.2    DeClerck, Y.A.3
  • 11
    • 33846051928 scopus 로고    scopus 로고
    • Mechanisms of invasion and metastasis in human neuroblastoma
    • Ara T., DeClerck Y.A. Mechanisms of invasion and metastasis in human neuroblastoma. Cancer Metastasis Rev 2006, 25:645-657.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 645-657
    • Ara, T.1    DeClerck, Y.A.2
  • 12
    • 33646525650 scopus 로고    scopus 로고
    • Plasma levels of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in patients with neuroblastoma
    • Granchi D., Garaventa A., Amato I., Paolucci P., Baldini N. Plasma levels of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in patients with neuroblastoma. Int J Cancer 2006, 119:146-151.
    • (2006) Int J Cancer , vol.119 , pp. 146-151
    • Granchi, D.1    Garaventa, A.2    Amato, I.3    Paolucci, P.4    Baldini, N.5
  • 13
    • 58249095935 scopus 로고    scopus 로고
    • Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells
    • Ara T., Song L., Shimada H., Keshelava N., Russell H.V., Metelitsa L.S., et al. Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells. Cancer Res 2009, 69:329-337.
    • (2009) Cancer Res , vol.69 , pp. 329-337
    • Ara, T.1    Song, L.2    Shimada, H.3    Keshelava, N.4    Russell, H.V.5    Metelitsa, L.S.6
  • 14
    • 50549098909 scopus 로고    scopus 로고
    • Paracrine inhibition of osteoblast differentiation induced by neuroblastoma cells
    • Granchi D., Baglìo S.R., Amato I., Giunti A., Baldini N. Paracrine inhibition of osteoblast differentiation induced by neuroblastoma cells. Int J Cancer 2008, 123:1526-1535.
    • (2008) Int J Cancer , vol.123 , pp. 1526-1535
    • Granchi, D.1    Baglìo, S.R.2    Amato, I.3    Giunti, A.4    Baldini, N.5
  • 15
    • 62649138786 scopus 로고    scopus 로고
    • Wnt pathway, an essential role in bone regeneration
    • Chen Y., Alman B.A. Wnt pathway, an essential role in bone regeneration. J Cell Biochem 2009, 106:353-362.
    • (2009) J Cell Biochem , vol.106 , pp. 353-362
    • Chen, Y.1    Alman, B.A.2
  • 16
    • 22044436959 scopus 로고    scopus 로고
    • How Wnt signaling affects bone repair by mesenchymal stem cells from the bone marrow
    • Gregory C.A., Gunn W.G., Reyes E., Smolarz A.J., Munoz J., Spees J.L., et al. How Wnt signaling affects bone repair by mesenchymal stem cells from the bone marrow. Ann NY Acad Sci 2005, 1049:97-106.
    • (2005) Ann NY Acad Sci , vol.1049 , pp. 97-106
    • Gregory, C.A.1    Gunn, W.G.2    Reyes, E.3    Smolarz, A.J.4    Munoz, J.5    Spees, J.L.6
  • 18
    • 40849083276 scopus 로고    scopus 로고
    • Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma
    • Qiang Y.W., Barlogie B., Rudikoff S., Shaughnessy J.D. Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma. Bone 2008, 42:669-680.
    • (2008) Bone , vol.42 , pp. 669-680
    • Qiang, Y.W.1    Barlogie, B.2    Rudikoff, S.3    Shaughnessy, J.D.4
  • 20
    • 24744439747 scopus 로고    scopus 로고
    • Prostate cancer cells promote osteoblastic bone metastases through Wnts
    • Hall C.L., Bafico A., Dai J., Aaronson S.A., Keller E.T. Prostate cancer cells promote osteoblastic bone metastases through Wnts. Cancer Res 2005, 65:7554-7560.
    • (2005) Cancer Res , vol.65 , pp. 7554-7560
    • Hall, C.L.1    Bafico, A.2    Dai, J.3    Aaronson, S.A.4    Keller, E.T.5
  • 21
    • 60249086335 scopus 로고    scopus 로고
    • The role of Dickkopf-1 in bone development, homeostasis, and disease
    • Pinzone J.J., Hall B.M., Thudi N.K., Vonau M., Qiang Y.W., Rosol T.J., et al. The role of Dickkopf-1 in bone development, homeostasis, and disease. Blood 2009, 113:517-525.
    • (2009) Blood , vol.113 , pp. 517-525
    • Pinzone, J.J.1    Hall, B.M.2    Thudi, N.K.3    Vonau, M.4    Qiang, Y.W.5    Rosol, T.J.6
  • 22
    • 43549108372 scopus 로고    scopus 로고
    • Serum concentrations of DKK-1 correlate with the extent of bone disease in patients with multiple myeloma
    • Kaiser M., Mieth M., Liebisch P., Oberländer R., Rademacher J., Jakob C., et al. Serum concentrations of DKK-1 correlate with the extent of bone disease in patients with multiple myeloma. Eur J Haematol 2008, 80:490-494.
    • (2008) Eur J Haematol , vol.80 , pp. 490-494
    • Kaiser, M.1    Mieth, M.2    Liebisch, P.3    Oberländer, R.4    Rademacher, J.5    Jakob, C.6
  • 23
    • 67349252622 scopus 로고    scopus 로고
    • Assessment of circulating Dickkopf-1 with a new two-site immunoassay in healthy subjects and women with breast cancer and bone metastases
    • Voorzanger-Rousselot N., Journe F., Doriath V., Body J.J., Garnero P. Assessment of circulating Dickkopf-1 with a new two-site immunoassay in healthy subjects and women with breast cancer and bone metastases. Calcif Tissue Int 2009, 84:348-354.
    • (2009) Calcif Tissue Int , vol.84 , pp. 348-354
    • Voorzanger-Rousselot, N.1    Journe, F.2    Doriath, V.3    Body, J.J.4    Garnero, P.5
  • 24
    • 69549111595 scopus 로고    scopus 로고
    • Clinical significance and prognostic value of serum Dickkopf-1 concentrations in patients with lung cancer
    • Le Sheng S., Huang G., Yu B., Qin W.X. Clinical significance and prognostic value of serum Dickkopf-1 concentrations in patients with lung cancer. Clin Chem 2009, 55:1656-1664.
    • (2009) Clin Chem , vol.55 , pp. 1656-1664
    • Le Sheng, S.1    Huang, G.2    Yu, B.3    Qin, W.X.4
  • 25
    • 66049103776 scopus 로고    scopus 로고
    • Serum Dickkopf-1 is increased and correlates with reduced bone mineral density in patients with thalassemia-induced osteoporosis. Reduction post-zoledronic acid administration
    • Voskaridou E., Christoulas D., Xirakia C., Varvagiannis K., Boutsikas G., Bilalis A., et al. Serum Dickkopf-1 is increased and correlates with reduced bone mineral density in patients with thalassemia-induced osteoporosis. Reduction post-zoledronic acid administration. Haematologica 2009, 94:725-728.
    • (2009) Haematologica , vol.94 , pp. 725-728
    • Voskaridou, E.1    Christoulas, D.2    Xirakia, C.3    Varvagiannis, K.4    Boutsikas, G.5    Bilalis, A.6
  • 27
    • 68149172533 scopus 로고    scopus 로고
    • Dickkopf-1 enhances inflammatory interaction between platelets and endothelial cells and shows increased expression in atherosclerosis
    • Ueland T., Otterdal K., Lekva T., Halvorsen B., Gabrielsen A., Sandberg W.J., et al. Dickkopf-1 enhances inflammatory interaction between platelets and endothelial cells and shows increased expression in atherosclerosis. Arterioscler Thromb Vasc Biol 2009, 29:1228-1234.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1228-1234
    • Ueland, T.1    Otterdal, K.2    Lekva, T.3    Halvorsen, B.4    Gabrielsen, A.5    Sandberg, W.J.6
  • 28
    • 73449088791 scopus 로고    scopus 로고
    • Clinical significance of serum DKK-1 in patients with gynecological cancer
    • Jiang T., Wang S., Huang L., Zhang S. Clinical significance of serum DKK-1 in patients with gynecological cancer. Int J Gynecol Cancer 2009, 19:1177-1181.
    • (2009) Int J Gynecol Cancer , vol.19 , pp. 1177-1181
    • Jiang, T.1    Wang, S.2    Huang, L.3    Zhang, S.4
  • 29
    • 0028911197 scopus 로고
    • Localized resectable neuroblastoma: results of the second study of the Italian Cooperative Group for Neuroblastoma
    • De Bernardi B., Conte M., Mancini A., Donfrancesco A., Alvisi P., Tomà P., et al. Localized resectable neuroblastoma: results of the second study of the Italian Cooperative Group for Neuroblastoma. J Clin Oncol 1995, 13:884-893.
    • (1995) J Clin Oncol , vol.13 , pp. 884-893
    • De Bernardi, B.1    Conte, M.2    Mancini, A.3    Donfrancesco, A.4    Alvisi, P.5    Tomà, P.6
  • 30
    • 0035990125 scopus 로고    scopus 로고
    • Italian Cooperative Group for Neuroblastoma: localized unresectable neuroblastoma: results of treatment based on clinical prognostic factors
    • Garaventa A., Boni L., Lo Piccolo M.S., Tonini G.P., Gambini C., Mancini A., et al. Italian Cooperative Group for Neuroblastoma: localized unresectable neuroblastoma: results of treatment based on clinical prognostic factors. Ann Oncol 2002, 13:956-964.
    • (2002) Ann Oncol , vol.13 , pp. 956-964
    • Garaventa, A.1    Boni, L.2    Lo Piccolo, M.S.3    Tonini, G.P.4    Gambini, C.5    Mancini, A.6
  • 31
    • 0038179739 scopus 로고    scopus 로고
    • Italian co-operative group for neuroblastoma: disseminated neuroblastoma in children older than one year at diagnosis: Comparable results with three consecutive high-dose protocols adopted by the Italian Co-Operative Group for Neuroblastoma
    • De Bernardi B., Nicolas B., Boni L., Indolfi P., Carli M., Cordero Di Montezemolo L., et al. Italian co-operative group for neuroblastoma: disseminated neuroblastoma in children older than one year at diagnosis: Comparable results with three consecutive high-dose protocols adopted by the Italian Co-Operative Group for Neuroblastoma. J Clin Oncol 2003, 21:1592-1601.
    • (2003) J Clin Oncol , vol.21 , pp. 1592-1601
    • De Bernardi, B.1    Nicolas, B.2    Boni, L.3    Indolfi, P.4    Carli, M.5    Cordero Di Montezemolo, L.6
  • 33
    • 33845939529 scopus 로고    scopus 로고
    • Correlation of modified Shimada classification with MYCN and 1p36 status detected by fluorescence in situ hybridization in neuroblastoma
    • Altungoz O., Aygun N., Tumer S., Ozer E., Olgun N., Sakizli M. Correlation of modified Shimada classification with MYCN and 1p36 status detected by fluorescence in situ hybridization in neuroblastoma. Cancer Genet Cytogenet 2007, 172:113-119.
    • (2007) Cancer Genet Cytogenet , vol.172 , pp. 113-119
    • Altungoz, O.1    Aygun, N.2    Tumer, S.3    Ozer, E.4    Olgun, N.5    Sakizli, M.6
  • 34
    • 0037417585 scopus 로고    scopus 로고
    • Standards for reporting of diagnostic accuracy steering group. Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative
    • Bossuyt P.M., Reitsma J.B., Bruns D.E., Gatsonis C.A., Glasziou P.P., Irwig L.M., et al. Standards for reporting of diagnostic accuracy steering group. Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. BMJ 2003, 326:41-44.
    • (2003) BMJ , vol.326 , pp. 41-44
    • Bossuyt, P.M.1    Reitsma, J.B.2    Bruns, D.E.3    Gatsonis, C.A.4    Glasziou, P.P.5    Irwig, L.M.6
  • 35
    • 0035928514 scopus 로고    scopus 로고
    • Systematic reviews in health care: systematic reviews of evaluations of diagnostic and screening tests
    • Deeks J.J. Systematic reviews in health care: systematic reviews of evaluations of diagnostic and screening tests. BMJ 2001, 323:157-162.
    • (2001) BMJ , vol.323 , pp. 157-162
    • Deeks, J.J.1
  • 36
    • 0034732151 scopus 로고    scopus 로고
    • Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53
    • Wang J., Shou J., Chen X. Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53. Oncogene 2000, 19:1843-1848.
    • (2000) Oncogene , vol.19 , pp. 1843-1848
    • Wang, J.1    Shou, J.2    Chen, X.3
  • 37
    • 1642545618 scopus 로고    scopus 로고
    • A functional genomics approach for the identification of putative tumor suppressor genes: Dickkopf-1 as suppressor of HeLa cell transformation
    • Mikheev A.M., Mikheeva S.A., Liu B., Cohen P., Zarbl H. A functional genomics approach for the identification of putative tumor suppressor genes: Dickkopf-1 as suppressor of HeLa cell transformation. Carcinogenesis 2004, 25:47-59.
    • (2004) Carcinogenesis , vol.25 , pp. 47-59
    • Mikheev, A.M.1    Mikheeva, S.A.2    Liu, B.3    Cohen, P.4    Zarbl, H.5
  • 38
    • 33847224852 scopus 로고    scopus 로고
    • The Wnt pathway regulator DKK1 is preferentially expressed in hormone-resistant breast tumors and in some common cancer types
    • Forget M.A., Turcotte S., Beauseigle D., Godin-Ethier J., Pelletier S., Martin J., et al. The Wnt pathway regulator DKK1 is preferentially expressed in hormone-resistant breast tumors and in some common cancer types. Br J Cancer 2007, 96:646-653.
    • (2007) Br J Cancer , vol.96 , pp. 646-653
    • Forget, M.A.1    Turcotte, S.2    Beauseigle, D.3    Godin-Ethier, J.4    Pelletier, S.5    Martin, J.6
  • 39
    • 34047270776 scopus 로고    scopus 로고
    • Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas
    • Yamabuki T., Takano A., Hayama S., Ishikawa N., Kato T., Miyamoto M., et al. Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas. Cancer Res 2007, 67:2517-2525.
    • (2007) Cancer Res , vol.67 , pp. 2517-2525
    • Yamabuki, T.1    Takano, A.2    Hayama, S.3    Ishikawa, N.4    Kato, T.5    Miyamoto, M.6
  • 40
    • 63449128528 scopus 로고    scopus 로고
    • Platelet is a major contributor to circulating levels of Dickkopf-1: clinical implications in patients with multiple myeloma
    • Voorzanger-Rousselot N., Goehrig D., Facon T., Clézardin P., Garnero P. Platelet is a major contributor to circulating levels of Dickkopf-1: clinical implications in patients with multiple myeloma. Br J Haematol 2009, 145:264-266.
    • (2009) Br J Haematol , vol.145 , pp. 264-266
    • Voorzanger-Rousselot, N.1    Goehrig, D.2    Facon, T.3    Clézardin, P.4    Garnero, P.5
  • 41
    • 34548693211 scopus 로고    scopus 로고
    • Dickkopf-1 is down-regulated by MYCN and inhibits neuroblastoma cell proliferation
    • Koppen A., Ait-Aissa R., Hopman S., Koster J., Haneveld F., Versteeg R., et al. Dickkopf-1 is down-regulated by MYCN and inhibits neuroblastoma cell proliferation. Cancer Lett 2007, 256:218-228.
    • (2007) Cancer Lett , vol.256 , pp. 218-228
    • Koppen, A.1    Ait-Aissa, R.2    Hopman, S.3    Koster, J.4    Haneveld, F.5    Versteeg, R.6
  • 42
    • 39849099343 scopus 로고    scopus 로고
    • Deregulated Wnt/beta-catenin program in high-risk neuroblastomas without MYCN amplification
    • Liu X., Mazanek P., Dam V., Wang Q., Zhao H., Guo R., et al. Deregulated Wnt/beta-catenin program in high-risk neuroblastomas without MYCN amplification. Oncogene 2008, 27:1478-1488.
    • (2008) Oncogene , vol.27 , pp. 1478-1488
    • Liu, X.1    Mazanek, P.2    Dam, V.3    Wang, Q.4    Zhao, H.5    Guo, R.6
  • 43
    • 67349153325 scopus 로고    scopus 로고
    • The Wnt receptor FZD1 mediates chemoresistance in neuroblastoma through activation of the Wnt/beta-catenin pathway
    • Flahaut M., Meier R., Coulon A., Nardou K.A., Niggli F.K., Martinet D., et al. The Wnt receptor FZD1 mediates chemoresistance in neuroblastoma through activation of the Wnt/beta-catenin pathway. Oncogene 2009, 28:2245-2256.
    • (2009) Oncogene , vol.28 , pp. 2245-2256
    • Flahaut, M.1    Meier, R.2    Coulon, A.3    Nardou, K.A.4    Niggli, F.K.5    Martinet, D.6
  • 44
    • 73149114384 scopus 로고    scopus 로고
    • The Wnt signaling pathway regulates Nalm-16 B-cell precursor acute lymphoblastic leukemic cell line survival and etoposide resistance
    • Thiago L.S., Costa E.S., Lopes D.V., Otazu I.B., Nowill A.E., Mendes F.A., et al. The Wnt signaling pathway regulates Nalm-16 B-cell precursor acute lymphoblastic leukemic cell line survival and etoposide resistance. Biomed Pharmacother 2010, 64:63-72.
    • (2010) Biomed Pharmacother , vol.64 , pp. 63-72
    • Thiago, L.S.1    Costa, E.S.2    Lopes, D.V.3    Otazu, I.B.4    Nowill, A.E.5    Mendes, F.A.6
  • 45
    • 77953413882 scopus 로고    scopus 로고
    • Networking of differentially expressed genes in human cancer cells resistant to methotrexate
    • Selga E., Oleaga C., Ramírez S., de Almagro M.C., Noé V., Ciudad C.J. Networking of differentially expressed genes in human cancer cells resistant to methotrexate. Genome Med 2009, 1:83.1-83.16.
    • (2009) Genome Med , vol.1
    • Selga, E.1    Oleaga, C.2    Ramírez, S.3    de Almagro, M.C.4    Noé, V.5    Ciudad, C.J.6
  • 46
    • 16544389047 scopus 로고    scopus 로고
    • Phase I study of the proteasome inhibitor bortezomib in pediatric patients with refractory solid tumors: a Children's Oncology Group study (ADVL0015)
    • Blaney S.M., Bernstein M., Neville K., Ginsberg J., Kitchen B., Horton T., et al. Phase I study of the proteasome inhibitor bortezomib in pediatric patients with refractory solid tumors: a Children's Oncology Group study (ADVL0015). J Clin Oncol 2004, 22:4804-4809.
    • (2004) J Clin Oncol , vol.22 , pp. 4804-4809
    • Blaney, S.M.1    Bernstein, M.2    Neville, K.3    Ginsberg, J.4    Kitchen, B.5    Horton, T.6
  • 47
    • 33646789993 scopus 로고    scopus 로고
    • Anti-cancer effects of bortezomib against chemoresistant neuroblastoma cell lines in vitro and in vivo
    • Michaelis M., Fichtner I., Behrens D., Haider W., Rothweiler F., Mack A., et al. Anti-cancer effects of bortezomib against chemoresistant neuroblastoma cell lines in vitro and in vivo. Int J Oncol 2006, 28:439-446.
    • (2006) Int J Oncol , vol.28 , pp. 439-446
    • Michaelis, M.1    Fichtner, I.2    Behrens, D.3    Haider, W.4    Rothweiler, F.5    Mack, A.6
  • 49
    • 34547582308 scopus 로고    scopus 로고
    • Bortezomib inhibits angiogenesis and reduces tumor burden in a murine model of neuroblastoma
    • Hamner J.B., Dickson P.V., Sims T.L., Zhou J., Spence Y., Ng C.Y., et al. Bortezomib inhibits angiogenesis and reduces tumor burden in a murine model of neuroblastoma. Surgery 2007, 142:185-191.
    • (2007) Surgery , vol.142 , pp. 185-191
    • Hamner, J.B.1    Dickson, P.V.2    Sims, T.L.3    Zhou, J.4    Spence, Y.5    Ng, C.Y.6
  • 50
    • 78650309653 scopus 로고    scopus 로고
    • A study to assess BHQ880 in combination with zoledronic acid in relapsed or refractory myeloma patients. August
    • A study to assess BHQ880 in combination with zoledronic acid in relapsed or refractory myeloma patients. August, 2008. http://clinicaltrials.gov/ct2/show/NCT00741377.
    • (2008)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.