Innate immune activation by the viral PAMP poly I:C potentiates pulmonary graft-versus-host disease after allogeneic hematopoietic cell transplant

Transplant Immunology

Volumn 24, Issue 2, 2011, Pages 83-93

  Kinnier, Christine V ^a   Martinu, Tereza ^a   M Gowdy, Kymberly ^a   Nugent, Julia L ^a   Kelly, Francine L ^a   Palmer, Scott M ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Allogeneic; Lymphocytic bronchiolitis; Monocytes; Poly I:C; Pulmonary graft versus host disease; Respiratory viral infection

Indexed keywords

POLYINOSINIC POLYCYTIDYLIC ACID;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN RECOGNITION; ARTICLE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL MATURATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GRAFT VERSUS HOST REACTION; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; LUNG FLUID; LUNG INFECTION; LUNG PARENCHYMA; LYMPHOCYTIC INFILTRATION; MALE; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; VIRUS INFECTION;

ADAPTIVE IMMUNITY; ANIMALS; ANTIGENS, CD3; CD4-POSITIVE T-LYMPHOCYTES; FLOW CYTOMETRY; GRAFT VS HOST DISEASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IMMUNITY, INNATE; LUNG; LUNG DISEASES; MICE; MICE, INBRED C57BL; MONOCYTES; MONOCYTES, ACTIVATED KILLER; POLY I-C; RESPIRATORY MUCOSA; RESPIRATORY TRACT INFECTIONS; T-LYMPHOCYTES, REGULATORY; TRANSPLANTATION, HOMOLOGOUS;

EID: 78650310185     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trim.2010.11.004     Document Type: Article

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