-
1
-
-
78650294464
-
The tumour suppressor C/EBPd inhibits FBXW7 expression and promotes mammary tumour metastasis
-
Balamurugan K, Wang J-M, Tsai H-H, Sharan S, Anver M, Leighty R, Sterneck E (2010) The tumour suppressor C/EBPd inhibits FBXW7 expression and promotes mammary tumour metastasis. EMBO J 29: 4106-4117
-
(2010)
EMBO J
, vol.29
, pp. 4106-4117
-
-
Balamurugan, K.1
Wang, J.-M.2
Tsai, H.-H.3
Sharan, S.4
Anver, M.5
Leighty, R.6
Sterneck, E.7
-
2
-
-
67549086678
-
Transforming growth factor-beta in breast cancer: Too much, too late
-
Barcellos-Hoff MH, Akhurst RJ (2009) Transforming growth factor-beta in breast cancer: too much, too late. Breast Cancer Res 11 : 202
-
(2009)
Breast Cancer Res
, vol.11
, pp. 202
-
-
Barcellos-Hoff, M.H.1
Akhurst, R.J.2
-
3
-
-
77957113912
-
Tumor suppressor Fbxw7 regulates TGFbeta signaling by targeting TGIF1 for degradation
-
Bengoechea-Alonso MT, Ericsson J (2010a) Tumor suppressor Fbxw7 regulates TGFbeta signaling by targeting TGIF1 for degradation. Oncogene 29: 5322-5328
-
(2010)
Oncogene
, vol.29
, pp. 5322-5328
-
-
Bengoechea-Alonso, M.T.1
Ericsson, J.2
-
4
-
-
77955342148
-
The ubiquitin ligase Fbxw7 controls adipocyte differentiation by targeting C/EBPalpha for degradation
-
Bengoechea-Alonso MT, Ericsson J (2010b) The ubiquitin ligase Fbxw7 controls adipocyte differentiation by targeting C/EBPalpha for degradation. Proc Natl Acad Sci USA 107: 11817-11822
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 11817-11822
-
-
Bengoechea-Alonso, M.T.1
Ericsson, J.2
-
5
-
-
78149330949
-
HIF-1alpha regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
-
Corzo CA, Condamine T, Lu L, Cotter MJ, Youn JI, Cheng P, Cho HI, Celis E, Quiceno DG, Padhya T, McCaffrey TV, McCaffrey JC, Gabrilovich DI (2010) HIF-1alpha regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment. J Exp Med 207: 2439-2453
-
(2010)
J Exp Med
, vol.207
, pp. 2439-2453
-
-
Corzo, C.A.1
Condamine, T.2
Lu, L.3
Cotter, M.J.4
Youn, J.I.5
Cheng, P.6
Cho, H.I.7
Celis, E.8
Quiceno, D.G.9
Padhya, T.10
McCaffrey, T.V.11
McCaffrey, J.C.12
Gabrilovich, D.I.13
-
6
-
-
77957350018
-
Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression
-
Doedens AL, Stockmann C, Rubinstein MP, Liao D, Zhang N, DeNardo DG, Coussens LM, Karin M, Goldrath AW, Johnson RS (2010) Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression. Cancer Res 70: 7465-7475
-
(2010)
Cancer Res
, vol.70
, pp. 7465-7475
-
-
Doedens, A.L.1
Stockmann, C.2
Rubinstein, M.P.3
Liao, D.4
Zhang, N.5
Denardo, D.G.6
Coussens, L.M.7
Karin, M.8
Goldrath, A.W.9
Johnson, R.S.10
-
7
-
-
70350418625
-
MTOR signaling at a glance
-
Laplante M, Sabatini DM (2009) mTOR signaling at a glance. J Cell Sci 122: 3589-3594
-
(2009)
J Cell Sci
, vol.122
, pp. 3589-3594
-
-
Laplante, M.1
Sabatini, D.M.2
-
8
-
-
51749095471
-
FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression
-
Mao JH, Kim IJ, Wu D, Climent J, Kang HC, DelRosario R, Balmain A (2008) FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression. Science 321: 1499-1502
-
(2008)
Science
, vol.321
, pp. 1499-1502
-
-
Mao, J.H.1
Kim, I.J.2
Wu, D.3
Climent, J.4
Kang, H.C.5
Delrosario, R.6
Balmain, A.7
-
9
-
-
10644269326
-
Fbxw7/ Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene
-
Mao JH, Perez-Losada J, Wu D, Delrosario R, Tsunematsu R, Nakayama KI, Brown K, Bryson S, Balmain A (2004) Fbxw7/ Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene. Nature 432: 775-779
-
(2004)
Nature
, vol.432
, pp. 775-779
-
-
Mao, J.H.1
Perez-Losada, J.2
Wu, D.3
Delrosario, R.4
Tsunematsu, R.5
Nakayama, K.I.6
Brown, K.7
Bryson, S.8
Balmain, A.9
-
10
-
-
33847348449
-
A gene-expression signature to predict survival in breast cancer across independent data sets
-
Naderi A, Teschendorff AE, Barbosa-Morais NL, Pinder SE, Green AR, Powe DG, Robertson JF, Aparicio S, Ellis IO, Brenton JD, Caldas C (2007) A gene-expression signature to predict survival in breast cancer across independent data sets. Oncogene 26: 1507-1516
-
(2007)
Oncogene
, vol.26
, pp. 1507-1516
-
-
Naderi, A.1
Teschendorff, A.E.2
Barbosa-Morais, N.L.3
Pinder, S.E.4
Green, A.R.5
Powe, D.G.6
Robertson, J.F.7
Aparicio, S.8
Ellis, I.O.9
Brenton, J.D.10
Caldas, C.11
-
11
-
-
77952718207
-
C/EBP{delta} targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/AP
-
Pawar SA, Sarkar TR, Balamurugan K, Sharan S, Wang J, Zhang Y, Dowdy SF, Huang AM, Sterneck E (2010) C/EBP{delta} targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/AP. Proc Natl Acad Sci USA 107: 9210-9215
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 9210-9215
-
-
Pawar, S.A.1
Sarkar, T.R.2
Balamurugan, K.3
Sharan, S.4
Wang, J.5
Zhang, Y.6
Dowdy, S.F.7
Huang, A.M.8
Sterneck, E.9
-
12
-
-
76049100577
-
HIF-1: Upstream and downstream of cancer metabolism
-
Semenza GL (2010) HIF-1: upstream and downstream of cancer metabolism. Curr Opin Genet Dev 20: 51-56
-
(2010)
Curr Opin Genet Dev
, vol.20
, pp. 51-56
-
-
Semenza, G.L.1
-
13
-
-
77958021483
-
CCAAT/enhancer binding protein delta (C/EBPdelta, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage
-
Wang J, Sarkar TR, Zhou M, Sharan S, Ritt DA, Veenstra TD, Morrison DK, Huang AM, Sterneck E (2010) CCAAT/enhancer binding protein delta (C/EBPdelta, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage. Proc Natl Acad Sci USA 107: 16131-16136
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 16131-16136
-
-
Wang, J.1
Sarkar, T.R.2
Zhou, M.3
Sharan, S.4
Ritt, D.A.5
Veenstra, T.D.6
Morrison, D.K.7
Huang, A.M.8
Sterneck, E.9
-
14
-
-
38549086019
-
FBW7 ubiquitin ligase: A tumour suppressor at the crossroads of cell division, growth and differentiation
-
Welcker M, Clurman BE (2008) FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation. Nat Rev Cancer 8: 83-93
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 83-93
-
-
Welcker, M.1
Clurman, B.E.2
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