The effect of small changes in hematocrit on nitric oxide transport in arterioles

Antioxidants and Redox Signaling

Volumn 14, Issue 2, 2011, Pages 175-185

  Sriram, Krishna ^a   Vázquez, Beatriz Y Salazar ^b   Yalcin, Ozlem ^c   Johnson, Paul C ^c   Intaglietta, Marcos ^c   Tartakovsky, Daniel M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSIDAD JUÁREZ DEL ESTADO DE DURANGO   (Mexico)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE; OXYGEN;

ARTERIOLE; ARTICLE; BLOOD FLOW VELOCITY; BLOOD VESSEL WALL; CIRCULATION; ERYTHROCYTE; HEMATOCRIT; HEMODYNAMIC MONITORING; MATHEMATICAL MODEL; OXYGEN TRANSPORT; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SHEAR STRESS;

ANIMALS; ARTERIOLES; ENDOTHELIUM, VASCULAR; HEMATOCRIT; HUMANS; MICROCIRCULATION; MODELS, BIOLOGICAL; NITRIC OXIDE; OXYGEN;

EID: 78650270599     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2010.3266     Document Type: Article

References (33)

1. Arnold WP, Mittal CK, Katsuki S, and Murad F. Nitric oxide activates guanylate cyclase and increases guanosine 3':5'-cyclic monophosphate levels in various tissue preparations. Proc Natl Acad Sci USA 74: 3203-3207, 1977.
2. Battiato I, Tartakovsky DM, Tartakovsky AM, and Scheibe T. On breakdown of macroscopic models of mixing-controlled heterogeneous reactions in porous media. Adv Water Resour 32: 1664-1673, 2009.
3. Buerk DG. Can we model nitric oxide biotransport? A survey of mathematical models for a simple diatomic molecule with surprisingly complex biological activity. Ann Rev Biomed Eng 3: 109-143, 2001.
4. Butler AR, Megson IL, and Wright PG. Diffusion of nitric oxide and scavenging by blood in the vasculature. Biochem Biophys Acta 1425: 168-176, 1998.
5. Chen X, Jaron D, Barbee KA, and Buerk DG. The influence of radial RBC distribution, blood velocity profiles, and gly-cocalyx on coupled NO=O2 transport. J Appl Physiol 100: 482-492, 2006.
6. Cheng C, Tempel D, Oostlander A, Helderman F, Gijsen F, Wentzel J, van Haperen R, Haitsma DB, Serruys PW, van der Steen AF, de Crom R, and Krams R. Rapamycin modulates the eNOS vs. shear stress relationship. Cardiovasc Res 78: 123-129, 2008.
7. Cokelet GR and Goldsmith HL. Decreased hydrodynamic resistance in the two-phase flow of blood through small vertical tubes at low flow rates. Circ Res 68: 1-17, 1991.
8. Fischkoff S and Vanderkooi JM. Oxygen diffusion in biological and artificial membranes determined by the fluorochrome pyrene. J Gen Physiol 65: 663-676, 1975.
9. Gundersen SI, Chen G, and Palmer AF. Mathematical model of NO and O2 transport in an arteriole facilitated by hemoglobin based O2 carriers. Biophys Chem 143: 1-17, 2009.
10. Intaglietta M, Johnson PC, and Winslow RM. Microvascular and tissue oxygen distribution. Cardiovasc Res 32: 632-643, 1996.
11. Kavdia M and Popel AS. Wall shear stress differentially affects NO level in arterioles for volume expanders and Hb-based O2 carriers. Microvasc Res 66: 49-58, 2003.
12. Kim S, Kong RL, Popel AS, Intaglietta M, and Johnson PC. A computer-based method for determination ofthe cell-free layer width in microcirculation. Microcirculation 13: 199-207, 2006.
13. Lamkin-Kennard KA, Buerk DG, and Jaron D. Interactions between NO and O2 in the microcirculation: a mathematical analysis. Microvasc Res 68: 38-50, 2004.
14. Lancaster JR. Simulation of the diffusion and reaction of endogenously produced nitric oxide. Proc Natl Acad Sci USA 91: 8137-8141, 1994.
15. Mahler M, Louy C, Homsher E, and Peskoff A. Reappraisal of diffusion, solubility, and consumption of oxygen in frog skeletal muscle, with applications to muscle energy balance. J Gen Physiol 86: 105-134, 1985.
16. Malinski T, Taha Z, Grunfeld S, Patton S, Kapturczak M, and Tomboulian P. Diffusion of nitric oxide in the aorta wall monitored in situ by porphyrinic microsensors. Biochem Biophys Res Commun 193: 1076-1082, 1993.
17. Martini J, Carpentier B, Chavez Negrete A, Frangos JA, and Intaglietta M. Paradoxical hypotension following increased hematocrit and blood viscosity. Am J Physiol Heart Circ Physiol 289: H2136-H2143, 2005.
18. Martini J, Tsai AG, Cabrales P, Johnson PC, and In-taglietta M. Increased cardiac output and microvascular blood flow during mild hemoconcentration in hamster window model. Am J Physiol Heart Circ Physiol 291: H310-H317, 2006.
19. Mashour GA and Boock RJ. Effects of shear stress on nitric oxide levels of human cerebral endothelial cells cultured in an artificial capillary system. Brain Res 842: 233-238, 1999.
20. McAllister TN and Frangos JA. Steady and transient fluid shear stress stimulate NO release in osteoblasts through distinct biochemical pathways. J Bone Mineral Res 14: 930-936, 1999.
21. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J 6: 3051-3064, 1992.
22. Pozrikidis C. Numerical Computation in Science and Engineering, 2nd edition. New York: Oxford University Press, 2008.
23. Pries AR, Neuhaus D, and Gaehtgens P. Blood viscosity in tube flow: dependence on diameter and hematocrit. Am J Physiol 263: H1770-H1778, 1992.
24. Roy B and Garthwaite J. Nitric oxide activation of guanylyl cyclase in cells revisited. Proc Natl Acad Sci USA 103: 12185-12190, 2006.
25. Salazar Vázquez BY, Cabrales P, Tsai AG, Johnson PC, and Intaglietta M. Lowering of blood pressure by increasing hematocrit with non nitric oxide scavenging red blood cells. Am J Respir Cell Mol Biol 38: 135-142, 2008.
26. Sharan M and Popel AS. A two-phase model for flow of blood in narrow tubes with increased effective viscosity near the wall. Biorheology 38: 415-428, 2001.
27. Tartakovsky AM, Tartakovsky DM, Scheibe TD, and Meakin P. Hybrid simulations of reaction-diffusion systems in porous media. SIAM J Sci Comput 30: 2799-2816, 2008.
28. Tsoukias NM. Nitric oxide bioavailability in the microcir-culation: insights from mathematical models. Microcircula-tion 15: 813-834, 2008.
29. Tsoukias NM and Popel AS. Erythrocyte consumption of nitric oxide in presence and absence of plasmabased hemoglobin. Am J Physiol Heart Circ Physiol 282: H2265-H2277, 2002.
30. Wang WC. A jump condition capturing finite difference scheme for elliptic interface problems. SIAM J Sci Comput 25: 1479-1496, 2004.
31. Weinbaum S, Tarbell JM, and Damiano ER. The structure and function of the endothelial glycocalyx layer. Annu Rev Biomed Eng 9: 121-167, 2007.
32. Weinbaum S, Zhang X, Han Y, Vink H, and Cowin SC. Mechanotransduction and flow across the endothelial gly-cocalyx. Proc Natl Acad Sci USA 100: 7988-7995, 2003.
33. Yalcin O, Choi C, Chatpun S, Intaglietta M, and Johnson PC. The dependence of cell-free layer thickness in arterioles on systemic hematocrit level. FASEB J 23: 949.7 (Abstract), 2009.